scholarly journals Clinical-pathological Characteristics and Prognostic Factors for Papillary Thyroid Microcarcinoma in the Elderly

2018 ◽  
Vol 9 (2) ◽  
pp. 256-262 ◽  
Author(s):  
Jing Tang ◽  
Hans B. Liu ◽  
Lujiao Yu ◽  
Xin Meng ◽  
Sean X. Leng ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
The Elderly ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Pathological Characteristics ◽  
Thyroid Microcarcinoma

The Prognostic Factors and Therapeutic Strategy for Papillary Thyroid Microcarcinoma

2008 ◽  
Vol 8 (3) ◽  
pp. 177 ◽  
Author(s):  
Kyung Min Kim ◽  
Min Su Cho ◽  
Yong Hyun Choi ◽  
Keum Seok Bae ◽  
Seong Joon Kang
Keyword(s):  
Prognostic Factors ◽  
Therapeutic Strategy ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Thyroid Microcarcinoma

scholarly journals Clinical features and prognostic factors in papillary thyroid microcarcinoma depends on age

2012 ◽  
Vol 82 (5) ◽  
pp. 281 ◽  
Author(s):  
Jin-Kyu Cho ◽  
Ju-Yeon Kim ◽  
Chi-Young Jeong ◽  
Eun-Jung Jung ◽  
Soon-Tae Park ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Clinical Features ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Thyroid Microcarcinoma

scholarly journals Long-term Outcomes and Prognostic Factors in Papillary Thyroid Microcarcinoma Patients with Distant Metastases

2021 ◽  
Author(s):  
Huai-Yu Weng ◽  
Ting Yan ◽  
Wang-Wang Qiu ◽  
Chuang Xi ◽  
Li-Ying Hou ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Radioactive Iodine ◽  
Distant Metastases ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Long Term Outcomes ◽  
Thyroid Microcarcinoma ◽  
Male Sex

Abstract PurposesDistant metastasis from papillary thyroid microcarcinoma (PTMC) is extremely rare and the long-term outcome and independent prognostic factors remain unclear.The present study aimed to investigate clinicopathological characteristics and evaluate the long-term outcomes and prognostic factors of PTMC patients with distant metastases (DM) who underwent surgery and radioactive iodine (131I) treatment.MethodsWe retrospectively reviewed the medical records of 13,441 patients with thyroid cancer (including 1,697 cases with PTMC) who underwent 131I treatment at our institution between January 2008 and December 2019. PTMC patients with distant metastases with sufficient clinical follow-up data were enrolled in this cohort study. The overall survival (OS) and progression-free survival (PFS) were analyzed by the Kaplan–Meier method and the prognostic factors were assessed by Cox proportional hazards. ResultsThirty-three PTMC patients with DM were enrolled in this study. The median follow-up was 75 months (range: 5–151 months).The 5-year and 10-year OS rates were 96.97% and 81.41%, respectively, and the 5-year and 10-year PFS rates were 90.46% and 69.68%, respectively. Multivariate analysis showed that male sex(P=0.005) , radioactive iodine refractory PTMC (P=0.033) and symptomatic DM (P=0.022) were significantly associated with worse 10-year PFS in PTMC patients with DM. No independent predictor related to poor 10-year OS found in the present study.ConclusionsThe prognosis of PTMC patients becomes worse after the development of DM. Male sex, radioactive iodine refractory PTMC and symptomatic DM were identified as independent factors associated with PFS.

Observation versus thyroidectomy for papillary thyroid microcarcinoma in the elderly

2016 ◽  
Vol 131 (2) ◽  
pp. 173-176 ◽  
Author(s):  
U C Megwalu
Keyword(s):  
Elderly Patients ◽  
Propensity Score Analysis ◽  
The Elderly ◽  
Hazard Ratio ◽  
Surgical Patients ◽  
Papillary Thyroid Microcarcinoma ◽  
Study Cohort ◽  
Papillary Thyroid ◽  
Thyroid Microcarcinoma ◽  
Score Analysis

AbstractObjective:To compare the effectiveness of non-surgical versus surgical therapy in elderly patients with papillary thyroid microcarcinoma.Methods:The study cohort included 2323 elderly patients (aged 65 years and over) diagnosed with papillary thyroid microcarcinoma between 1988 and 2009, identified in the Surveillance, Epidemiology, and End Results 18 database of the National Cancer Institute.Results:The five-year overall survival rate was 23 per cent for non-surgical patients compared with 91 per cent for surgical patients (p < 0.0001). Unadjusted analysis revealed significantly improved survival in surgical patients compared with non-surgical patients (hazard ratio = 0.06; p < 0.0001). Propensity score analysis also revealed significantly improved survival in surgical patients compared with non-surgical patients (hazard ratio = 0.11; p < 0.0001).Conclusion:Thyroidectomy appears to provide a survival benefit for elderly patients with papillary thyroid microcarcinoma. High-quality prospective studies are needed to better evaluate the comparative effectiveness of immediate thyroidectomy versus observation for elderly patients with papillary thyroid microcarcinoma.

Prognostic factors for lymph node metastases in patients with papillary thyroid microcarcinoma

2019 ◽  
Author(s):  
Julia Sastre ◽  
Gordillo Andrea Cruz ◽  
Silvia Aznar ◽  
Visitacion Alvarez ◽  
Belvis Torres ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Thyroid Microcarcinoma ◽  
Node Metastases
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