scholarly journals Dual Color Imaging from a Single BF2-Azadipyrromethene Fluorophore Demonstrated in vivo for Lymph Node Identification

2021 ◽  
Vol 18 (7) ◽  
pp. 1541-1553
Author(s):  
Niamh Curtin ◽  
Dan Wu ◽  
Ronan Cahill ◽  
Anwesha Sarkar ◽  
Pól Mac Aonghusa ◽  
...  
Keyword(s):  
2020 ◽  
Author(s):  
Niamh Curtin ◽  
Dan Wu ◽  
Ronan A. Cahill ◽  
Anwesha Sarkar ◽  
Pól Mac Aonghusa ◽  
...  

<p>Dual color fluorescence imaging has been achieved in the highly complex biomedical scenario of lymph node mapping. Emissions at 700 and 800 nm can be achieved from a single fluorophore by establishing molecular and aggregate forms. Fluorophore was compatible with clinical systems for fluorescence guided surgery and no toxicity was observed in high dosage testing.</p>


2020 ◽  
Author(s):  
Niamh Curtin ◽  
Dan Wu ◽  
Ronan A. Cahill ◽  
Anwesha Sarkar ◽  
Pól Mac Aonghusa ◽  
...  

<p>Dual color fluorescence imaging has been achieved in the highly complex biomedical scenario of lymph node mapping. Emissions at 700 and 800 nm can be achieved from a single fluorophore by establishing molecular and aggregate forms. Fluorophore was compatible with clinical systems for fluorescence guided surgery and no toxicity was observed in high dosage testing.</p>


2020 ◽  
Vol 12 (9) ◽  
pp. 10183-10192
Author(s):  
Fatemeh Ostadhossein ◽  
Dinabandhu Sar ◽  
Indu Tripathi ◽  
Julio Soares ◽  
Edward E. Remsen ◽  
...  
Keyword(s):  

2005 ◽  
Vol 65 (10) ◽  
pp. 4246-4252 ◽  
Author(s):  
Kensuke Yamauchi ◽  
Meng Yang ◽  
Ping Jiang ◽  
Norio Yamamoto ◽  
Mingxu Xu ◽  
...  

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Mayeul Collot ◽  
Christian D Wilms ◽  
Asma Bentkhayet ◽  
Païkan Marcaggi ◽  
Kiri Couchman ◽  
...  

The great demand for long-wavelength and high signal-to-noise Ca2+ indicators has led us to develop CaRuby-Nano, a new functionalizable red calcium indicator with nanomolar affinity for use in cell biology and neuroscience research. In addition, we generated CaRuby-Nano dextran conjugates and an AM-ester variant for bulk loading of tissue. We tested the new indicator using in vitro and in vivo experiments demonstrating the high sensitivity of CaRuby-Nano as well as its power in dual color imaging experiments.


2021 ◽  
Vol 351 ◽  
pp. 109064
Author(s):  
Jacob F. Norman ◽  
Bahar Rahsepar ◽  
Jad Noueihed ◽  
John A. White
Keyword(s):  

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