scholarly journals Gamma Protocadherin Expression in the Embryonic Chick Nervous System

2007 ◽  
pp. 8-11 ◽  
Author(s):  
Kenneth D. Cronin ◽  
Anthony A. Capehart
Keyword(s):  
Nervous System ◽  
Embryonic Chick

scholarly journals Primary Cultures of Embryonic Chicken Neurons for Sensitive Cell-Based Assay of Botulinum Neurotoxin: Implications for Therapeutic Discovery

2007 ◽  
Vol 12 (3) ◽  
pp. 370-377 ◽  
Author(s):  
Andrea M. Stahl ◽  
Gordon Ruthel ◽  
Edna Torres-Melendez ◽  
Tara A. Kenny ◽  
Rekha G. Panchal ◽  
...  
Keyword(s):  
Nervous System ◽  
Botulinum Toxin ◽  
Neutralizing Antibodies ◽  
Botulinum Neurotoxin ◽  
Potent Inhibitor ◽  
Primary Cultures ◽  
Embryonic Chick ◽  
Sensitive Cell ◽  
Botulinum Neurotoxin A ◽  
Therapeutic Compounds

Botulinum toxin is an exceedingly potent inhibitor of neurotransmission across the neuromuscular junction, causing flaccid paralysis and death. The potential for misuse of this deadly poison as a bioweapon has added a greater urgency to the search for effective therapeutics. The development of sensitive and efficient cell-based assays for the evaluation of toxin antagonists is crucial to the rapid and successful identification of therapeutic compounds. The authors evaluated the sensitivity of primary cultures from 4 distinct regions of the embryonic chick nervous system to botulinum neurotoxin A (BoNT/A) cleavage of synaptosomal-associated protein of 25 kD (SNAP-25). Although differences in sensitivity were apparent, SNAP-25 cleavage was detectable in neuronal cells from each of the 4 regions within 3 h at BoNT/A concentrations of 1 nM or lower. Co-incubation of chick neurons with BoNT/A and toxin-neutralizing antibodies inhibited SNAP-25 cleavage, demonstrating the utility of these cultures for the assay of BoNT/A antagonists. ( Journal of Biomolecular Screening 2007:370-377)

scholarly journals Integration of human model neurons (NT2) into embryonic chick nervous system

2009 ◽  
Vol 239 (2) ◽  
pp. 496-504 ◽  
Author(s):  
Grzegorz Podrygajlo ◽  
Christoph Wiegreffe ◽  
Martin Scaal ◽  
Gerd Bicker
Keyword(s):  
Nervous System ◽  
Human Model ◽  
Embryonic Chick

scholarly journals Immunohistochemical Localization of Netrin-1 in the Embryonic Chick Nervous System

1997 ◽  
Vol 17 (14) ◽  
pp. 5466-5479 ◽  
Author(s):  
A. John MacLennan ◽  
Diana L. McLaurin ◽  
Lianne Marks ◽  
Emily N. Vinson ◽  
Marylynn Pfeifer ◽  
...  
Keyword(s):  
Nervous System ◽  
Immunohistochemical Localization ◽  
Embryonic Chick

scholarly journals A family of molecules related to collapsin in the embryonic chick nervous system

Neuron ◽  
1995 ◽  
Vol 14 (6) ◽  
pp. 1131-1140 ◽  
Author(s):  
Yuling Luo ◽  
Iain Shepherd ◽  
Jie Li ◽  
Michael J Renzi ◽  
Susannah Chang ◽  
...  
Keyword(s):  
Nervous System ◽  
Embryonic Chick

Effect of Ouabain on the Innervated and Noninnervated Embryonic Chick Heart

1975 ◽  
Vol 53 (6) ◽  
pp. 1005-1006 ◽  
Author(s):  
J. Lelorier ◽  
N. Minejima ◽  
F. E. Shideman
Keyword(s):  
Nervous System ◽  
Inotropic Response ◽  
Embryonic Chick ◽  
Endogenous Catecholamines ◽  
Embryonic Life ◽  
Chick Heart ◽  
Embryonic Chick Heart ◽  
Sympathetic Nervous ◽  
Embryo Heart ◽  
Two Stages

Attempts to assess the importance of the role played by endogenous catecholamines in the positive inotropic response to ouabain have produced contradictory results. The sympathetic nervous system is not present in the 4-day-old chicken embryo heart but is fully developed after 7 days of embryonic life. This was confirmed by the fact 4-day-old hearts do not respond to tyramine and cocaine while the usual positive inotropic and chronotropic responses were observed when these drugs were administered to 7-day-old hearts. In spite of this difference the positive inotropic response to ouabain was virtually identical at these two stages of development.

Tetraspanins expressed in the embryonic chick nervous system

FEBS Letters ◽  
1999 ◽  
Vol 461 (1-2) ◽  
pp. 86-90 ◽  
Author(s):  
Jeanette C. Perron ◽  
John L. Bixby
Keyword(s):  
Nervous System ◽  
Embryonic Chick

An in vitro cell culture system for the aggregation of embryonic chick central nervous system neurons

1997 ◽  
Vol 1 (4) ◽  
pp. 344-346 ◽  
Author(s):  
Hubert Monnerie ◽  
Odile Boespflug-Tanguy ◽  
Bernard Dastugue ◽  
Annie Meiniel
Keyword(s):  
Central Nervous System ◽  
Cell Culture ◽  
Nervous System ◽  
Culture System ◽  
Embryonic Chick ◽  
Cell Culture System ◽  
In Vitro Cell Culture
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