Effect of Ouabain on the Innervated and Noninnervated Embryonic Chick Heart

1975 ◽  
Vol 53 (6) ◽  
pp. 1005-1006 ◽  
Author(s):  
J. Lelorier ◽  
N. Minejima ◽  
F. E. Shideman
Keyword(s):  
Nervous System ◽  
Inotropic Response ◽  
Embryonic Chick ◽  
Endogenous Catecholamines ◽  
Embryonic Life ◽  
Chick Heart ◽  
Embryonic Chick Heart ◽  
Sympathetic Nervous ◽  
Embryo Heart ◽  
Two Stages

Attempts to assess the importance of the role played by endogenous catecholamines in the positive inotropic response to ouabain have produced contradictory results. The sympathetic nervous system is not present in the 4-day-old chicken embryo heart but is fully developed after 7 days of embryonic life. This was confirmed by the fact 4-day-old hearts do not respond to tyramine and cocaine while the usual positive inotropic and chronotropic responses were observed when these drugs were administered to 7-day-old hearts. In spite of this difference the positive inotropic response to ouabain was virtually identical at these two stages of development.

Lineage and development of the parasympathetic nervous system of the embryonic chick heart

1998 ◽  
Vol 198 (3) ◽  
pp. 171-184 ◽  
Author(s):  
M. E. Verberne ◽  
A. C. Gittenberger-de Groot ◽  
R. E. Poelmann
Keyword(s):  
Nervous System ◽  
Parasympathetic Nervous System ◽  
Embryonic Chick ◽  
Chick Heart ◽  
Embryonic Chick Heart

Ontogenesis of K and Na fluxes in embryonic chick heart

1960 ◽  
Vol 199 (4) ◽  
pp. 613-618 ◽  
Author(s):  
Richard L. Klein
Keyword(s):  
Active Transport ◽  
Transport Mechanism ◽  
Early Embryogenesis ◽  
Embryonic Chick ◽  
Active Transport Mechanism ◽  
Chick Heart ◽  
Embryonic Chick Heart ◽  
Embryo Heart

Cation analyses showed that ventricular and atrial K increased gradually during early embryogenesis, reached a plateau by 13 days, and then decreased at hatching. Myocardial Na was extremely high at 2 days, fell markedly by 7 days, and then more gradually through hatching. K influx and efflux in isolated ventricles were relatively high at 7 days, fell at 13 days, and then increased shortly after hatching. Intracellular K exchangeability was relatively constant throughout development at 70%. Na exchange was more complex than K. Intracellular Na exchangeability was only 7% at 7 days, but rose gradually during development to 73% shortly after hatching. The presence of an active transport mechanism in the embryo heart by at least 2 days of incubation was suggested. Enzymatic and electrophysiological correlates were discussed.

Acetylcholinesterase-acetylcholine, an enzyme system essential to rhythmicity in the preneural embryonic chick heart

1966 ◽  
Vol 154 (3) ◽  
pp. 675-683 ◽  
Author(s):  
George Hugo Paff ◽  
Robert Joseph Boucek ◽  
Thorne Parsons Glander
Keyword(s):  
Enzyme System ◽  
Embryonic Chick ◽  
Chick Heart ◽  
Embryonic Chick Heart
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