scholarly journals Interaction of cyanine dyes with nucleic acids. 7. Carbocyanine dyes, substituted in polymethine chain, as possible probes for fluorescent nucleic acid detection

2001 ◽  
Vol 17 (2) ◽  
pp. 169-177 ◽  
Author(s):  
S. S. Lukashov ◽  
M. Yu. Losytskyy ◽  
Yu. L. Slominskii ◽  
S. M. Yarmoluk
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Cyanine Dyes ◽  
Nucleic Acid Detection ◽  
Polymethine Chain ◽  
Carbocyanine Dyes

scholarly journals Interaction of cyanine dyes with nucleic acids. Meso-methylsubstituted trimethincyanines, as possible probes for fluorescent nucleic acid detection

2001 ◽  
Vol 17 (5) ◽  
pp. 448-454 ◽  
Author(s):  
S. S. Lukashov ◽  
I. E. Makovenko ◽  
M. Yu. Losytskyy ◽  
Yu. L. Slominskii ◽  
S. M. Yarmoluk
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Cyanine Dyes ◽  
Nucleic Acid Detection

scholarly journals A nuclease protection ELISA assay for colorimetric and electrochemical detection of nucleic acids

2019 ◽  
Vol 11 (8) ◽  
pp. 1027-1034 ◽  
Author(s):  
Jessica E. Filer ◽  
Robert B. Channon ◽  
Charles S. Henry ◽  
Brian J. Geiss
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Electrochemical Detection ◽  
Nucleic Acid Detection ◽  
Elisa Assay

The NP-ELISA combines traditional nuclease protection with optical and electrochemical enzymatic readout for nucleic acid detection.

Preparation of monomethine cyanine dyes for nucleic acid detection

1998 ◽  
Vol 37 (3) ◽  
pp. 205-211 ◽  
Author(s):  
Todor G Deligeorgiev ◽  
Daphinka A Zaneva ◽  
Seok Hong Kim ◽  
Ram W Sabnis
Keyword(s):  
Nucleic Acid ◽  
Cyanine Dyes ◽  
Nucleic Acid Detection

Recent advance in exonuclease Ⅲ-assisted target signal amplification strategy for nucleic acid detection

2021 ◽  
Author(s):  
hongyu liu ◽  
Yuhao You ◽  
Youzhuo Zhu ◽  
Heng Zheng
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Molecular Diagnostics ◽  
Mutation Analysis ◽  
Signal Amplification ◽  
Nucleic Acid Detection ◽  
Target Signal ◽  
Forensic Investigations ◽  
Exo Iii ◽  
Amplification Strategy

Detection of nucleic acids have become significantly important in molecular diagnostics, genetics therapy, mutation analysis, forensic investigations and biomedical development, and so on. In recent years, exonuclease Ⅲ (Exo III)...

Synthesis of novel monomeric and homodimeric cyanine dyes with thioacetyl substituents for nucleic acid detection

2007 ◽  
Vol 72 (1) ◽  
pp. 28-32 ◽  
Author(s):  
Todor Deligeorgiev ◽  
Nikolai Gadjev ◽  
Aleksey Vasilev ◽  
Karl-Heinz Drexhage ◽  
S.M. Yarmoluk
Keyword(s):  
Nucleic Acid ◽  
Cyanine Dyes ◽  
Nucleic Acid Detection

A catalytic DNA circuit-programmed and enzyme-powered autonomous DNA machine for nucleic acid detection

The Analyst ◽  
2019 ◽  
Vol 144 (20) ◽  
pp. 5923-5927 ◽  
Author(s):  
Shuang Liu ◽  
Chen Xin ◽  
Xiaoxiao Yu ◽  
Zhenbo Ding ◽  
Shufeng Liu
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Nucleic Acid Detection ◽  
One Step ◽  
Catalytic Dna ◽  
Dna Machine

A catalytic DNA circuit-programmed and enzyme-powered autonomous DNA machine was proposed for one-step, isothermal and dual-level amplified detection of nucleic acids.

scholarly journals Isomerization and Properties of Isomers of Carbocyanine Dyes

Sci ◽  
2018 ◽  
Vol 1 (1) ◽  
pp. 5 ◽  
Author(s):  
Pavel Pronkin ◽  
Alexander Tatikolov
Keyword(s):  
Phenyl Ring ◽  
Steric Effect ◽  
Cyanine Dyes ◽  
Information Storage ◽  
Polymethine Chain ◽  
Trans Isomers ◽  
Trans Form ◽  
Polar Solvents ◽  
Carbocyanine Dyes ◽  
Nonpolar Solvents

One of the important features of polymethine (cyanine) dyes is isomerization around one of C–C bonds of the polymethine chain. In this review, spectral properties of the isomers, photoisomerization and thermal back isomerization of carbocyanine dyes, mostly meso-substituted carbocyanine dyes, are considered. meso-Alkyl-substituted thiacarbocyanine dyes are present in polar solvents mainly as cis isomers and, hence, exhibit no photoisomerization, whereas in nonpolar solvents, in which the dyes are in the trans form, photoisomerization takes place. In contrast, the meso-substituted dyes 3,3′-dimethyl-9-phenylthiacarbocyanine and 3,3′-diethyl-9-(2-hydroxy-4-methoxyphenyl)thiacarbocyanine occur as trans isomers and exhibit photoisomerization in both polar and nonpolar solvents. The behavior of these dyes may be explained by the fact that the phenyl ring of the substituent in their molecules can be twisted at some angle, removing the substituent from the plane of the molecule and reducing its steric effect on the conformation of the trans isomer. In some cases, photoisomerization of cis isomers of meso-substituted carbocyanine dyes is also observed (for some meso-alkyl-substituted dyes complexed with DNA and chondroitin-4-sulfate; for 3,3′-diethyl-9-methoxythiacarbocyanine in moderate polarity solvents). The cycle photoisomerization–thermal back isomerization of cyanine dyes can be used in various systems of information storage and deserves further investigation using modern research methods.

NAIL: Nucleic Acid detection using Isotachophoresis and Loop-mediated isothermal amplification

Lab on a Chip ◽  
2015 ◽  
Vol 15 (7) ◽  
pp. 1697-1707 ◽  
Author(s):  
Mark D. Borysiak ◽  
Kevin W. Kimura ◽  
Jonathan D. Posner
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Mobile Phone ◽  
Isothermal Amplification ◽  
Nucleic Acid Detection ◽  
Complex Matrices ◽  
Loop Mediated Isothermal Amplification

The NAIL device integrates isotachophoresis and loop-mediated isothermal amplification (LAMP) with mobile phone detection to extract, amplify, and detect nucleic acids from complex matrices in less than one hour.

Intercalating Cyanine Dyes for Nucleic Acid Detection

2009 ◽  
Vol 2 (1) ◽  
pp. 1-26 ◽  
Author(s):  
Todor Deligeorgiev ◽  
Stefka Kaloyanova ◽  
Juan Vaquero
Keyword(s):  
Nucleic Acid ◽  
Cyanine Dyes ◽  
Nucleic Acid Detection
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