Catalytic Nucleophilic Addition of 3, 5-Dialkyl-4-nitroisoxazoles to Trifluoromethyl Ketones on Water

2018 ◽  
Vol 38 (5) ◽  
pp. 1155 ◽  
Author(s):  
Jingjing Wang ◽  
Feng Li ◽  
Yan Xu ◽  
Juan Wang ◽  
Ziyan Wu ◽  
...  
Keyword(s):  
Nucleophilic Addition ◽  
Trifluoromethyl Ketones

ChemInform Abstract: Silver Salts and DBU Cooperatively Catalyzed Nucleophilic Addition/Cyclization of Propargylic Alcohols with Trifluoromethyl Ketones.

ChemInform ◽  
2015 ◽  
Vol 46 (36) ◽  
pp. no-no
Author(s):  
Jingjing Wang ◽  
Wei-Guang Kong ◽  
Feng Li ◽  
Jie Liu ◽  
Qin Shen ◽  
...  
Keyword(s):  
Nucleophilic Addition ◽  
Propargylic Alcohols ◽  
Trifluoromethyl Ketones ◽  
Silver Salts

Silver salts and DBU cooperatively catalyzed nucleophilic addition/cyclization of propargylic alcohols with trifluoromethyl ketones

2015 ◽  
Vol 13 (19) ◽  
pp. 5399-5406 ◽  
Author(s):  
Jingjing Wang ◽  
Wei-Guang Kong ◽  
Feng Li ◽  
Jie Liu ◽  
Qin Shen ◽  
...  
Keyword(s):  
Nucleophilic Addition ◽  
Silver Salt ◽  
Efficient Synthesis ◽  
Propargylic Alcohols ◽  
Trifluoromethyl Ketones ◽  
Silver Salts

A general and efficient synthesis of trifluoromethyl substituted 5-alkylidene-1,3-dioxolane using a silver salt and DBU cooperatively catalyzed nucleophilic addition/cyclization of propargylic alcohols and trifluoromethyl ketones is described.

scholarly journals “On Water” Nucleophilic Addition of Pyrazolones to Trifluoromethyl Ketones

2020 ◽  
Vol 40 (5) ◽  
pp. 1323
Author(s):  
Liang Luo ◽  
Xiaomei Cao ◽  
Guowei Lai ◽  
Jinxiang Liu ◽  
Haiqing Luo ◽  
...  
Keyword(s):  
Nucleophilic Addition ◽  
Trifluoromethyl Ketones

Recent Progress in Chemosensors Using Aldehyde-bearing Fluorophores for the Detection of Specific Analytes and their Bioimaging

2019 ◽  
Vol 26 (21) ◽  
pp. 4003-4028 ◽  
Author(s):  
Fangjun Huo ◽  
Yaqiong Zhang ◽  
Caixia Yin
Keyword(s):  
Biomedical Research ◽  
Nucleophilic Addition ◽  
Recent Progress ◽  
Biological Imaging ◽  
Tissue Imaging ◽  
Fluorescence Probes ◽  
Biological Applications ◽  
Convenient Procedure ◽  
Nucleophilic Mechanism

In recent years, aldehyde-appended fluorescence probes have attracted increasing attention. Fluorescent biological imaging includes many modern applications for cell and tissue imaging in biomedical research. Meanwhile, the nucleophilic mechanism is a very simple and convenient procedure for the preparation of aldehyde-sensing probes. This tutorial review focuses on aldehyde-bearing chemosensors based on nucleophilic addition mechanism with biological applications.

Formation of spiro adduct from N-methyl-N-(2,4,6-trinitrophenyl)glycine anion

1989 ◽  
Vol 54 (2) ◽  
pp. 440-445 ◽  
Author(s):  
Vladimír Macháček ◽  
Alexandr Čegan ◽  
Miloš Sedlák ◽  
Vojeslav Štěrba
Keyword(s):  
Nmr Spectroscopy ◽  
Dimethyl Sulfoxide ◽  
Equilibrium Constant ◽  
Mole Fraction ◽  
Nucleophilic Addition ◽  
Adduct Formation ◽  
First Case ◽  
C Nmr

The intramolecular nucleophilic addition of N-methyl-N-(2,4,6-trinitrophenyl)glycine anion in methanol-dimethyl sulfoxide mixtures produces spiro[(3-methyl-5-oxazolidinone)-2,1'-(2',4',6'-trinitrobenzenide)]. The spiro adduct has been identified by means of 1H and 13C NMR spectroscopy. This is the first case when the formation of a Meisenheimer adduct with carboxylate ion is observed. Logarithm of the equilibrium constant of adduct formation increases linearly with the mole fraction of dimethyl sulfoxide in its mixture with methanol.

Regioselective Functionalization of N-Fused Heteroaromatics via FeCl3-Catalyzed Nucleophilic Addition to Activated N-Heterocycles

Synthesis ◽  
2020 ◽  
Author(s):  
Ikyon Kim ◽  
Sung June Kim ◽  
Sunhee Lee
Keyword(s):  
Aromatic Compounds ◽  
Nucleophilic Addition ◽  
Chemical Space ◽  
Wide Range ◽  
Regioselective Functionalization

AbstractBroadening of nitrogen-fused heteroaromatic chemical space such as indolizine and pyrrolo[1,2-a]pyrazine was achieved via FeCl­3-catalyzed nucleophilic addition of these N-fused aromatic compounds to a wide range of azolinium systems generated in situ, leading to novel N-fused heteroaromatic scaffolds with dearomatized N-heterocyclic substituents regioselectively. Nucleophilic addition of indolizines and pyrrolo[1,2-a]pyrazines mainly occurred at the C1 position of the isoquinoliniums and at the C4 site of the quinoliniums.

A Highly Efficient Asymmetric Biomimetic Aldol Reaction of Glycinates and Trifluoromethyl Ketones via Carbonyl Catalysis

2021 ◽  
Author(s):  
Aolin Cheng ◽  
Liangliang Zhang ◽  
Qinghai Zhou ◽  
Tao Liu ◽  
Jing Cao ◽  
...  
Keyword(s):  
Aldol Reaction ◽  
Trifluoromethyl Ketones ◽  
Highly Efficient
Sign in / Sign up

Export Citation Format

Share Document