Microwave-Assisted Synthesis of 3-Substituted Indole Derivatives via Three-Component Domino Reaction

2018 ◽  
Vol 38 (4) ◽  
pp. 855 ◽  
Author(s):  
Wei Lin ◽  
Xiuxiu Hu ◽  
Yazhen Wang ◽  
Shuai Song ◽  
Mengye Zhang ◽  
...  
2021 ◽  
Vol 33 (4) ◽  
pp. 781-784
Author(s):  
E. Erdag

In this study, ten 3-substituted indole derivatives at the 3rd position of indole nucleus were synthesized via Mannich reaction with microwave assisted synthesis and the conventional reflux heating method. Microwave assisted synthesis is more preferrable than reflux method since the microwave irradiation lead to a higher product yields with better purity and improved energy efficiency with shortened reaction time. The structures of 3-substituted indole derivatives were characterized by FT-IR, elemental analysis, 1H NMR and 13C NMR spectroscopy


2017 ◽  
Vol 19 (11) ◽  
pp. 708-713 ◽  
Author(s):  
Wei Lin ◽  
Yong-Xiang Zheng ◽  
Zhan Xun ◽  
Zhi-Bin Huang ◽  
Da-Qing Shi

Heterocycles ◽  
2021 ◽  
Vol 103 (1) ◽  
pp. 65
Author(s):  
Gopinathan Anilkumar ◽  
Thaipparambil Aneeja ◽  
C M A Afsina

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