scholarly journals Chiral Metal-Organic Framework [Cu(S-mal)(bpy)]n Used for Separation of Racemates in High Performance Liquid Chromatography

2016 ◽  
Vol 74 (10) ◽  
pp. 819 ◽  
Author(s):  
Cong Hu ◽  
Li Li ◽  
Na Yang ◽  
Ziheng Zhang ◽  
Shengming Xie ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Homochiral Metal–Organic Framework [Co(L)(bpe)2(H2O)2]·H2O Used for Separation of Racemates in High-Performance Liquid Chromatography

2021 ◽  
Author(s):  
Yunyan Yu ◽  
Baoyan Yuan ◽  
Cong Hu ◽  
Nan Fu ◽  
Nayan Xu ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Chiral Stationary Phase ◽  
Metal Organic Framework ◽  
Hplc Separation ◽  
Relative Standard ◽  
Metal Organic ◽  
Cyclohexanedicarboxylic Acid ◽  
Organic Framework

Abstract A homochiral metal–organic framework (MOF) comprising [Co(L)(bpe)2(H2O)2]·H2O was prepared using (1R,2R)-(−)-1,2-cyclohexanedicarboxylic acid (H2L) and 1,2-bis(4-pyridyl)-ethylene as organic ligands. The homochiral MOF [Co(L)(bpe)2(H2O)2]·H2O was explored as chiral stationary phase (CSP) for high-performance liquid chromatography (HPLC) separation of racemates. Nine racemates including naphthol, alcohol, diol, amine, ketone, ether and organic acid were well separated on the homochiral MOF [Co(L)(bpe)2(H2O)2]·H2O column (250 mm long × 4.6 mm i.d.). The relative standard deviation for five replicate separations of 1,1′-bi-2-naphthol is 0.69% for the retention time, indicating that the good reproducibility and stability of the homochiral MOF column for HPLC enantioseparation. The results indicated that the homochiral MOF as CSP is practical, which promotes the application of homochiral MOFs in HPLC.

scholarly journals Reusable and sustainable graphene oxide/metal–organic framework-74/Fe3O4/polytyramine nanocomposite for simultaneous trace level quantification of five fluoroquinolones in egg samples by high performance liquid chromatography

2021 ◽  
Vol 4 (02) ◽  
pp. 5-24
Author(s):  
Fatemeh Pourbahman ◽  
Mohsen Zeeb ◽  
Amirhossein Monzavi ◽  
Zahra Khodadadi ◽  
Seyed Saied Homami
Keyword(s):  
High Performance Liquid Chromatography ◽  
Graphene Oxide ◽  
Liquid Chromatography ◽  
High Performance ◽  
Solid Phase ◽  
Metal Organic Framework ◽  
Oxidative Polymerization ◽  
X Ray ◽  
Metal Organic ◽  
Organic Framework

A nanohybrid material termed graphene oxide/metal-organic framework-74/Fe3O4/polytyramine (GO/MOF-74/Fe3O4­/PTy) was fabricated and applied in magnetic dispersive micro-solid phase extraction (MD-µ-SPE) coupled with high performance liquid chromatography (HPLC) for simultaneous determination of fluoroquinolones compounds including, ofloxacin, ciprofloxacin, lomefloxacin, enrofloxacin and sperfloxacin in egg samples. The GO/MOF-74/Fe3O4/PTy nanocomposite was fabricated through an in situ synthesis of MOF-74 in the presence of magnetic GO and followed with an oxidative polymerization of tyramine using horsedish peroxide (HRP) enzyme. The modifier agents improved the merits of the nanoporous sorbent. Extraction protocols based on GO/MOF nanocomposites have various benefit such as, the high stability, the tunable porosity, the fast mast transfer and reasonable enrichment factor. The fabricated material was characterized via energy dispersive x-ray analysis (EDX), the scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), and the x-ray diffraction (XRD). The calibration curves revealed linearity (0.992 ≤ r2 ≤ 0.997) in the ranges of 1.0-475.0, 0.5-350.0, 0.5-350.0, 0.5-375.0 and 1.5-300.0 ng mL-1 with limit of detections (LODs, S/N=3) of 0.3, 0.1, 0.2, 0.1 and 0.4 ng mL-1 for ofloxacin, ciprofloxacin, lomefloxacin, enrofloxacin and sperfloxacin, respectively. The intra-assay (≤7.7%, n = 9) and inter-assay (≤7.0%, n = 9) precisions along with accuracy less than 9.0% were obtained.

Reverse-phase high performance liquid chromatography separation of positional isomers on a MIL-53(Fe) packed column

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 40094-40102 ◽  
Author(s):  
Zhiming Yan ◽  
Wenmin Zhang ◽  
Jia Gao ◽  
Yifen Lin ◽  
Jianrong Li ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Metal Organic Framework ◽  
Packed Column ◽  
Positional Isomers ◽  
Reverse Phase ◽  
Liquid Chromatography Separation ◽  
Metal Organic ◽  
First Time

The application of the metal–organic framework (MOF) MIL-53(Fe) as a novel stationary phase for reverse-phase high performance liquid chromatography (HPLC) separation of positional isomers is described for the first time.

Research of the Processes of Chromatographic Analysis of Medicines on HKUST-1 Metal-Organic Framework Structures

2020 ◽  
pp. 122-136
Author(s):  
E.B. Markova ◽  
A.S. Savchenko ◽  
A.G. Cherednichenko ◽  
Yu.M. Averina ◽  
V.S. Boldyrev
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Organic Solvents ◽  
Chromatographic Analysis ◽  
High Performance ◽  
Metal Organic Framework ◽  
Degree Of Separation ◽  
Bet Method ◽  
Metal Organic ◽  
Research Show

The paper studies the process of analysis of tetracycline and paracetamol with the use of the HKUST-1 organometallic framework sorbent by high performance liquid chromatography. To obtain experimental data using the previously described technique, a sample of the material under consideration was synthesized and its physicochemical properties were studied. It has been established that individual sorbent particles have an octahedral shape and have a porous structure capable of adsorbing chemical compounds of various nature. The specific surface of the sample was calculated using the BET method and was Ssp = 551.3 m2/g. The study notes that when water or aqueous-organic media are used as eluents for chromatographic analysis, sorbents based on HKUST-1 have low stability; their degradation is observed when passing eluent solutions in an amount equal to 300--500 volumes of the chromatographic column. When only organic solvents are used for chromatographic analysis of tetracycline and paracetamol in the temperature range of 25--45 °C, no decomposition of the HKUST-1 sorbent and no degradation of the analyzed drugs are observed. Findings of research show that the efficiency of the eluent increases in the tetrahydrofuran--methanol--acetonitrile series. For all organic solvents used, the retention times were determined, the degree of separation, HETP, and the speed of response were calculated at various temperatures. A complex of studies has proved the possibility of using the organometallic sorbent HKUST-1 for the effective separation of drug mixtures by high-performance liquid chromatography

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