Reverse-phase high performance liquid chromatography separation of positional isomers on a MIL-53(Fe) packed column

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 40094-40102 ◽  
Author(s):  
Zhiming Yan ◽  
Wenmin Zhang ◽  
Jia Gao ◽  
Yifen Lin ◽  
Jianrong Li ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Metal Organic Framework ◽  
Packed Column ◽  
Positional Isomers ◽  
Reverse Phase ◽  
Liquid Chromatography Separation ◽  
Metal Organic ◽  
First Time

The application of the metal–organic framework (MOF) MIL-53(Fe) as a novel stationary phase for reverse-phase high performance liquid chromatography (HPLC) separation of positional isomers is described for the first time.

scholarly journals A Pair of Novel Sulfonyl-Containing N-Acetyldopamine Dimeric Enantiomers From Aspongopus chinensis

2020 ◽  
Vol 15 (3) ◽  
pp. 1934578X2091127
Author(s):  
Li Liao ◽  
Yong-Ming Yan ◽  
Te Xu ◽  
Hou-Lin Xia ◽  
Yong-Xian Cheng
Keyword(s):  
High Performance Liquid Chromatography ◽  
Biological Activity ◽  
Liquid Chromatography ◽  
Renal Fibrosis ◽  
High Performance ◽  
Racemic Mixture ◽  
Spectroscopic Methods ◽  
Liquid Chromatography Separation ◽  
New Compounds ◽  
First Time

A pair of novel sulfonyl-containing N-acetyldopamine dimer enanitomers, (±)-aspongamide E (1), a new ester 2-aminoethyl ( E)-hex-2-enoate (2), along with 3 known compounds (3-5) were isolated from Aspongopus chinensis. Their structures were determined by spectroscopic methods. Compound 1 is a racemic mixture, chiral high-performance liquid chromatography separation followed by electronic circular dichroism calculations assigned the absolute configurations of 2 enantiomers of 1. Compounds 3-5 were isolated from A. chinensis for the first time. The biological activity of the selected new compounds against renal fibrosis was evaluated.

scholarly journals Homochiral Metal–Organic Framework [Co(L)(bpe)2(H2O)2]·H2O Used for Separation of Racemates in High-Performance Liquid Chromatography

2021 ◽  
Author(s):  
Yunyan Yu ◽  
Baoyan Yuan ◽  
Cong Hu ◽  
Nan Fu ◽  
Nayan Xu ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Chiral Stationary Phase ◽  
Metal Organic Framework ◽  
Hplc Separation ◽  
Relative Standard ◽  
Metal Organic ◽  
Cyclohexanedicarboxylic Acid ◽  
Organic Framework

Abstract A homochiral metal–organic framework (MOF) comprising [Co(L)(bpe)2(H2O)2]·H2O was prepared using (1R,2R)-(−)-1,2-cyclohexanedicarboxylic acid (H2L) and 1,2-bis(4-pyridyl)-ethylene as organic ligands. The homochiral MOF [Co(L)(bpe)2(H2O)2]·H2O was explored as chiral stationary phase (CSP) for high-performance liquid chromatography (HPLC) separation of racemates. Nine racemates including naphthol, alcohol, diol, amine, ketone, ether and organic acid were well separated on the homochiral MOF [Co(L)(bpe)2(H2O)2]·H2O column (250 mm long × 4.6 mm i.d.). The relative standard deviation for five replicate separations of 1,1′-bi-2-naphthol is 0.69% for the retention time, indicating that the good reproducibility and stability of the homochiral MOF column for HPLC enantioseparation. The results indicated that the homochiral MOF as CSP is practical, which promotes the application of homochiral MOFs in HPLC.

scholarly journals Reusable and sustainable graphene oxide/metal–organic framework-74/Fe3O4/polytyramine nanocomposite for simultaneous trace level quantification of five fluoroquinolones in egg samples by high performance liquid chromatography

2021 ◽  
Vol 4 (02) ◽  
pp. 5-24
Author(s):  
Fatemeh Pourbahman ◽  
Mohsen Zeeb ◽  
Amirhossein Monzavi ◽  
Zahra Khodadadi ◽  
Seyed Saied Homami
Keyword(s):  
High Performance Liquid Chromatography ◽  
Graphene Oxide ◽  
Liquid Chromatography ◽  
High Performance ◽  
Solid Phase ◽  
Metal Organic Framework ◽  
Oxidative Polymerization ◽  
X Ray ◽  
Metal Organic ◽  
Organic Framework

A nanohybrid material termed graphene oxide/metal-organic framework-74/Fe3O4/polytyramine (GO/MOF-74/Fe3O4­/PTy) was fabricated and applied in magnetic dispersive micro-solid phase extraction (MD-µ-SPE) coupled with high performance liquid chromatography (HPLC) for simultaneous determination of fluoroquinolones compounds including, ofloxacin, ciprofloxacin, lomefloxacin, enrofloxacin and sperfloxacin in egg samples. The GO/MOF-74/Fe3O4/PTy nanocomposite was fabricated through an in situ synthesis of MOF-74 in the presence of magnetic GO and followed with an oxidative polymerization of tyramine using horsedish peroxide (HRP) enzyme. The modifier agents improved the merits of the nanoporous sorbent. Extraction protocols based on GO/MOF nanocomposites have various benefit such as, the high stability, the tunable porosity, the fast mast transfer and reasonable enrichment factor. The fabricated material was characterized via energy dispersive x-ray analysis (EDX), the scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), and the x-ray diffraction (XRD). The calibration curves revealed linearity (0.992 ≤ r2 ≤ 0.997) in the ranges of 1.0-475.0, 0.5-350.0, 0.5-350.0, 0.5-375.0 and 1.5-300.0 ng mL-1 with limit of detections (LODs, S/N=3) of 0.3, 0.1, 0.2, 0.1 and 0.4 ng mL-1 for ofloxacin, ciprofloxacin, lomefloxacin, enrofloxacin and sperfloxacin, respectively. The intra-assay (≤7.7%, n = 9) and inter-assay (≤7.0%, n = 9) precisions along with accuracy less than 9.0% were obtained.

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