scholarly journals Técnicas de alimentação na promoção das competências oro-motoras do recém-nascido prétermo: a scoping review

2021 ◽  
Vol 20 (1) ◽  
pp. 489-538
Author(s):  
Ana Lúcia Brantes ◽  
Maria Alice dos Santos Curado ◽  
Inês Rebelo Cruz
Keyword(s):  
Motor Skills ◽  
Scoping Review ◽  
Motor Development ◽  
Oral Feeding ◽  
Google Scholar ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Feeding Method ◽  
Central Register ◽  
Feeding Methods

Introducción: La alimentación oral es una actividad sensoriomotora muy compleja y exigente en relación con la coordinación oromotora del recién nacido prematuro requiriendo de los enfermeros la implementación de cuidados neuroprotectores. En el cuidado de enfermería para recién nacidos prematuros, no hay consenso sobre la elección de la técnica de alimentación oral más adecuada para el desarrollo de habilidades oromotoras, lo que ciertamente influirá en la autonomía de alimentación.Objetivo: Identificar y mapear la literatura científica, las técnicas de la alimentación oral promotores de las competencias oromotoras del recién nacido prematuro.Método: Se realizó una scoping review c que permitió el mapeo de artículos publicados en cuatro bases de datos: Medline; CINAHL; Cochrane Central Register of Controlled Trials y Scielo y no publicados (Google scholar, tesis de maestría y doctorado), entre 2000 y 2018.Resultados: Se incluyeron 28 estudios, de los cuales 21 son primarios, seis son secundarios y una tesis de doctorado. De estos surgieron tres técnicas de alimentación (biberón, taza y finger-feeding). Biberón aparece como un promotor de patrones de succión más maduros; la taza aparece como el más abierto, pero poco consensuado con respecto a los beneficios para el desarrollo oromotor y finger-feeding aparece como un facilitador del entrenamiento de succión y complementario a la lactancia materna.Conclusión: Las publicaciones analizadas se centran principalmente en aspectos de estabilidad hemodinámica, aumento de peso y autonomía alimentaria, con el consiguiente alta hospitalaria temprana. Por lo tanto, es esencial comprender cómo cada técnica promueve el desarrollo de habilidades oromotoras, y también es esencial contemplar los deseos y expectativas de los padres con respecto a la alimentación, como la lactancia materna exclusiva. Background: Oral feeding is a highly complex and coordinated sensorimotor activity for the preterm infants, requiring nurses to implement neuroprotective care. In nursing care, there is no consensus on the choice of the most appropriate oral feeding method for the development of oro-motor skills and the consequent feeding autonomy of the preterm infant. Objective: identify and map, in the scientific literature, the oral feeding method that promotes the development of oro-motor skills in preterm in preterm infants.Method: A scoping review was carried out with a research that allowed the mapping of articles published in databases (Medline, CINAHL, Cochrane Central Register of Controlled Trials and Scielo) and unpublished (Google scholar, master's and doctoral theses), between 2000 and 2018.Results: This scoping review included 28 studies: 21 are primary studies, 6 secondary studies and a doctoral thesis. Three feeding methods emerged (bottle, cup and finger-feeding). The bottle appears as a promoter of more mature suction patterns; the cup is the must studied method but little consensual regarding the benefits for oro-motor development and finger-feeding appears as a facilitator of suction training and breastfeeding.Conclusion: The publications focus mainly on aspects of hemodynamic stability, weight gain and feeding autonomy, with consequent early hospital discharge. It is therefore essential to understand how each method promotes the development of oro-motor skills, and it is also essential to contemplate the wishes and expectations of parents regarding food, such as exclusive breastfeeding. Introdução: A alimentação oral é uma atividade sensoriomotora altamente complexa e exigente relativamente à coordenação oro-motora do recém-nascido pré-termo, requerendo dos enfermeiros a implementação de cuidados neuroprotetores. Nos cuidados de enfermagem ao recém-nascido pré-termo, não existe consenso na escolha da técnica de alimentação oral mais adequada ao desenvolvimento das competências oro-motoras, o que decerto vai influenciar a autonomia alimentar. Objetivo: Identificar e mapear na literatura científica, as técnicas de alimentação oral promotoras das competências oro-motoras do recém-nascido pré-termo. Método: Foi realizada uma scoping review com uma pesquisa que permitiu o mapeamento de artigos publicados em bases de dados (Medline, CINAHL, Cochrane Central Register of Controlled Trials e Scielo) e não publicados (Google Académico, teses de mestrado e doutoramento), entre o ano 2000 e 2018.Resultados: Selecionaram-se 28 estudos, 21 primários, 6 secundários e uma tese de doutoramento. Destes emergiram três técnicas de alimentação (biberão, copo e finger-feeding). O biberão surge como promotor de padrões de sucção mais maturos; o copo surge como o mais descortinado, mas pouco consensual relativamente aos benefícios para o desenvolvimento oro-motor e o finger-feeding surge como facilitadora do treino da sucção e complementar da amamentação.Conclusão: As publicações analisadas focam-se sobretudo em aspetos de estabilidade hemodinâmica, de ganho ponderal e da autonomia alimentar, com consequente alta hospitalar precoce. É por isso essencial compreender de que forma cada técnica promove o desenvolvimento das competências oro-motoras, sendo também essencial contemplar os desejos e expectativas dos pais quanto à alimentação, como por exemplo a realização da amamentação exclusiva.

scholarly journals Antimicrobial Lock Therapy in Clinical Practice: A Scoping Review Protocol

2020 ◽  
Vol 3 (1) ◽  
pp. 16
Author(s):  
Aniello Alfieri ◽  
Sveva Di Franco ◽  
Maria Beatrice Passavanti ◽  
Maria Caterina Pace ◽  
Agata Stanga ◽  
...  
Keyword(s):  
Scoping Review ◽  
Grey Literature ◽  
Open Science ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Study Selection ◽  
Central Register ◽  
Lock Therapy ◽  
Science Framework ◽  
Meta Analyses

Our objective is to review the scientific literature on the use of antimicrobial lock therapy (ALT). To achieve this result, our scoping review will address the following seven key questions: (1) Who are the patients who will benefit from this technique? (2) What are the techniques utilized? (3) What are the settings in which the technique is performed? (4) When the technique is performed? (5) Why the technique is performed? (6) How the technique is performed? (7) In how much amount, of such technique performed? This review considers all studies published in full and in peer-reviewed journals, with no restrictions on language, on the year of publication and age of the participants. Both randomized controlled trials and observational studies will be included. This scoping review has been planned on a five-stage framework: 1. Identifying the review question; 2. identifying relevant studies; 3. study selection; 4. charting the data; 5. collating, summarizing, and reporting the results. It is conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines. The databases utilized will include MEDLINE via PubMed, EMBASE and Cochrane Central Register of Controlled Trials and Grey Literature. SCOPING REVIEW REGISTRATION: Open Science Framework https://osf.io/vphwm/.

scholarly journals Contributo das terapias integrativas na sexualidade da mulher com neoplasia da mama: scoping review

2021 ◽  
Vol 4 (1) ◽  
pp. 99-110
Author(s):  
Filomena Paulo ◽  
Manuela Ferreira ◽  
Regilnaldo Filho
Keyword(s):  
Systematic Reviews ◽  
Scoping Review ◽  
Allied Health ◽  
Information Science ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Cochrane Database ◽  
Central Register

Enquadramento: o tratamento do cancro da mama traz consigo terapêuticas agressivas e invasivas, trazendo alterações a nível físico e psicológico que afetam a vida da mulher e a vivência da sua sexualidade. Objetivo: mapear o contributo das terapias integrativas na sexualidade da mulher com cancro da mama. Metodologia: a Scoping Review foi construída seguindo as recomendações da extensão PRISMA. A estratégia de pesquisa incluiu as bases de dados: CINAHL Complete; MEDLINE Complete; Nursing & Allied Health Collection: Comprehensive; Cochrane Central Register of Controlled Trials; Cochrane Database of Systematic Reviews; Cochrane Methodology Register; Library, Information Science & Technology Abstracts; MedicLatina, via EBSCOhost - Research Databases, Google Académico, PubMed, B-On, LILACS, MEDLINE e SCIELO. Foi definido como limite cronológico janeiro de 1999 a março de 2020. O corpus da revisão ficou constituído por cinco artigos científicos. Resultados: os estudos analisados são unânimes: demostrando que o recurso às terapias integrativas por parte das mulheres com cancro de mama, mastectomizadas, refletem em efeitos positivos na saúde das mesmas.  Conclusão: as terapias integrativas promovem nas mulheres, através da harmonia dos seus próprios recursos, trazendo efeitos positivos na vivência da sua sexualidade.

Functional cortical changes associated with shoulder instability – a systematic review

2021 ◽  
pp. 175857322110190
Author(s):  
Morissa F Livett ◽  
Deborah Williams ◽  
Hayley Potter ◽  
Melinda Cairns
Keyword(s):  
Systematic Review ◽  
Joint Instability ◽  
Glenohumeral Joint ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Cortical Function ◽  
High Quality Research ◽  
Central Register ◽  
Rehabilitative Measures ◽  
Randomised Controlled

Background Glenohumeral joint instability is associated with structural deficits and/or alterations in sensory and motor processing; however, a proportion of patients with glenohumeral joint instability fail to respond to surgical and rehabilitative measures. This systematic review aimed to establish if functional cortical changes occur in patients with glenohumeral joint instability. Methods AMED, CINAHL, Cochrane Central Register of Controlled Trials, Embase, Medline, PEDro, Pubmed, PsychINFO and Scopus were searched from inception to 17 March 2021. Randomised controlled trials and non-randomised trials were included and quality was appraised using the Downs and Black tool. Results One thousand two hundred seventy-nine records were identified of which five were included in the review. All studies showed altered cortical function when comparing instability patients with healthy controls and included areas associated with higher cortical functions. Discussion The findings of this systematic review offer some insight as to why interventions addressing peripheral pathoanatomical factors in patients with glenohumeral joint instability may fail in some cases due to functional cortical changes. However, data are of moderate to high risk of bias. Further high-quality research is required to ascertain the degree of functional cortical changes associated with the type and duration of glenohumeral joint instability.

O papel da fisioterapia no tratamento das cefaleias: revisão de literatura

2016 ◽  
pp. 33-42
Author(s):  
Débora Wanderley ◽  
Joaquim José de Souza Costa Neto ◽  
Marcelo Moraes Valença ◽  
Daniella Araújo de Oliveira
Keyword(s):  
Controlled Trials ◽  
Cochrane Central Register ◽  
Central Register

A intolerância aos movimentos, incapacidade do pescoço e alterações nos músculos pericranianos são aspectos que podem interferir durante as crises de migrânea. A presença destes achados tornou a fisioterapia uma modalidade terapêutica alternativa para as cefaleias. Assim, as desordens estruturais e comportamentais musculares podem promover modificações na biomecânica da cabeça e região cervical, bem como limitações na mobilidade cervical no paciente com cefaleia, as quais podem ser tratadas por meio de diferentes modalidades fisioterapêuticas. O objetivo deste estudo foi revisar as publicações mais relevantes sobre o papel da fisioterapia no tratamento das cefaleias, a fim de fundamentar e direcionar o tratamento não farmacológico destes pacientes. Foi feito um levantamento da literatura, entre setembro/2015 e maio/2016, nas bases de dados MEDLINE/ PubMed, LILACS e Cochrane Central Register of Controlled Trials - CENTRAL, buscando ensaios clínicos randomizados e quasi randomizados sobre o tema. Os descritores do MeSH/DeCS utilizados foram: 'cefaleia', 'modalidades de fisioterapia', e seus equivalentes em inglês. Foram identificados 589 artigos, dos quais 19 foram incluídos, segundo os critérios de elegibilidade. De acordo com os resultados dos estudos avaliados, a fisioterapia promove melhora da cefaleia, dos sintomas associados e das disfunções musculoesqueléticas relacionadas. Entre as modalidades utilizadas estão correção postural, mobilização da coluna, alongamento muscular, técnicas de relaxamento, massagem, exercícios ativos ou passivos, entre outras. Devido à baixa qualidade metodológica da maioria dos estudos, são necessários novos ensaios controlados e randomizados, baseados nos critérios diagnósticos da ICHD, utilizando protocolos descritos de maneira mais detalhada e reprodutível, incluindo a avaliação de efeitos adversos.

Reducción de eventos cardiovasculares de Lomitapida versus Estatinas en pacientes con diagnóstico de hipercolesterolemia familiar. Protocolo de revisión sistemática.

10.52011/0097 ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Maritza Auxiliadora Torres Valdez ◽  
Lorena Alexandra Muñoz Avila ◽  
Carlos Enrique Ortega Espinoza ◽  
Franklin Geovany Mora Bravo ◽  
Diego Fernando Barzallo Zeas
Keyword(s):  
Controlled Trials ◽  
Cochrane Central Register ◽  
Electronic Library ◽  
Central Register ◽  
Revisión Sistemática

Introducción: La hipercolesterolemia familiar (HF) un trastorno genético autosómico dominante que produce hipercolesterolemia y desarrollo prematuro de enfermedades cardiovasculares. Las estatinas han sido el medicamento de elección en estos pacientes, sin embargo, un buen porcentaje de pacientes no pueden alcanzar sus objetivos terapéuticas con las dosis máximas recomendadas por lo que la Lomitapida se podría establecer como una nueva alternativa de tratamiento. Objetivo: El objetivo de esta revisión sistemática es determinar si la Lomitapida reduce los eventos cardiovasculares en pacientes con diagnóstico de Hipercolesterolemia familiar comparado con estatinas. Métodos: Se incluirán ensayos controlados aleatorios (ECA) y cuasialeatorios de pacientes con diagnóstico de HF. Las medidas de resultado primarias: 1. Niveles de LDL, HDL pos tratamiento. 2. Presencia de eventos cardiovasculares. Las búsquedas electrónicas se realizarán en PUBMED, The Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE y Scientific electronic library (Scielo). La evaluación del riesgo de sesgo se utilizará la herramienta de Cochrane. Las medidas del efecto del tratamiento serán las diferencias de medias (DM) y los intervalos de confianza (IC) del 95%. La evaluación de heterogeneidad se realizará mediante la inspección visual del diagrama de embudo. La evaluación de la calidad de la evidencia se realizará usando la evaluación GRADE.

scholarly journals Meta-Analysis: Randomized Trials of Lactobacillus plantarum on Immune Regulation Over the Last Decades

2021 ◽  
Vol 12 ◽  
Author(s):  
Wei Zhao ◽  
Chuantao Peng ◽  
Hafiz Arbab Sakandar ◽  
Lai-Yu Kwok ◽  
Wenyi Zhang
Keyword(s):  
Meta Analysis ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Central Register ◽  
Tnf Α ◽  
Ifn Γ ◽  
The Mean ◽  
Regulatory Effects ◽  
Mean Differences ◽  
Necrosis Factor

Lactobacillus (L.) plantarum strains, belong to lactic acid bacteria group, are considered indispensable probiotics. Here, we performed meta-analysis to evaluate the regulatory effects of L. plantarum on the immunity during clinical trials. This meta-analysis was conducted by searching across four most common literature databases, namely, Cochrane Central Register of Controlled Trials, Web of Science, Embase, and PubMed. Clinical trial articles that met the inclusion and exclusion criteria were analyzed by Review Manager (version 5.3). p-value < 0.05 of the total effect was considered statistically significant. Finally, total of 677 references were retrieved, among which six references and 18 randomized controlled trials were included in the meta-analysis. The mean differences observed at 95% confidence interval: interleukin (IL)-4, −0.48 pg/mL (−0.79 to −0.17; p < 0.05); IL-10, 9.88 pg/mL (6.52 to 13.2; p < 0.05); tumor necrosis factor (TNF)-α, −2.34 pg/mL (−3.5 to −1.19; p < 0.05); interferon (IFN)-γ, −0.99 pg/mL (−1.56 to −0.41; p < 0.05). Therefore, meta-analysis results suggested that L. plantarum could promote host immunity by regulating pro-inflammatory and anti-inflammatory cytokines.

scholarly journals Musculoskeletal Injuries Among Females in the Military: A Scoping Review

2020 ◽  
Author(s):  
Pauline Barbeau ◽  
Alan Michaud ◽  
Candyce Hamel ◽  
Danielle Rice ◽  
Becky Skidmore ◽  
...  
Keyword(s):  
Risk Factors ◽  
Scoping Review ◽  
Stress Fractures ◽  
Musculoskeletal Injuries ◽  
Future Research ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Increased Risk ◽  
Military Members ◽  
The Military

ABSTRACT Introduction Musculoskeletal injuries (MSKi) are a common challenge for those in military careers. Compared to their male peers, reports indicate that female military members and recruits are at greater risk of suffering MSKi during training and deployment. The objectives of this study were to identify the types and causes of MSKi among female military personnel and to explore the various risk factors associated with MSKi. Materials and Methods A scoping review was conducted over a 4-month time frame of English language, peer-reviewed studies published from 1946 to 2019. Search strategies for major biomedical databases (e.g., MEDLINE; Embase Classic + Embase; and the following EBM Reviews—Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, Health Technology Assessment, and the NHS Economic Evaluation Database) were developed by a senior medical information specialist and included 2,891 titles/abstracts. Study selection and data collection were designed according to the Population, Concept, and Context framework. Studies were included if the study population provided stratified data for females in a military context. Results From a total of 2,287 citations captured from the literature searches, 168 peer-reviewed publications (144 unique studies) were eligible for inclusion. Studies were identified from across 10 countries and published between 1977 and 2019. Study designs were primarily prospective and retrospective cohorts. Most studies assessed both prevalence/incidence and risk factors for MSKi (62.50%), with few studies assessing cause (13.69%). For MSKi of female recruits compared to active female members, the prevalence was higher (19.7%-58.3% vs. 5.5%-56.6%), but the incidence (0.02%-57.7% vs. 13.5%-71.9%) was lower. The incidence of stress fractures was found to be much higher in female recruits than in active members (1.6%-23.9% vs. 2.7%). For anthropometric risk factors, increased body fat was a predictor of MSKi, but not stress fractures. For physiological risk factors for both female military groups, being less physically fit, later menarche, and having no/irregular menses were predictors of MSKi and stress fractures. For biomechanical risk factors, among female recruits, longer tibial length and femoral neck diameter increased the risk of stress fractures, and low foot arch increased risk of an ankle sprain. For female active military members, differences in shoulder rotation and bone strength were associated with risk of MSKi. For biological sex, being female compared to male was associated with an increased risk of MSKi, stress fractures, and general injuries. The consequences of experiencing MSKi for active military included limited duties, time off, and discharge. For recruits, these included missed training days, limited duty days, and release. Conclusions This scoping review provides insight into the current state of the evidence regarding the types and causes of MSKi, as well as the factors that influence MSKi among females in the military. Future research endeavors should focus on randomized controlled trials examining training paradigms to see if women are more susceptible. The data presented in the scoping review could potentially be used to develop training strategies to mitigate some of the identified barriers that negatively impact women from pursuing careers in the military.

scholarly journals Azithromycin in patients with Covid-19; a systematic review and metanalysis

2021 ◽  
Author(s):  
Luis Ayerbe ◽  
Ivo Forgnone ◽  
Carlos Risco-Risco ◽  
Maria Perez-Pinar ◽  
Salma Ayis
Keyword(s):  
Systematic Review ◽  
Clinical Severity ◽  
Future Research ◽  
Controlled Trials ◽  
Clinical Settings ◽  
Cochrane Central Register ◽  
Random Effects Models ◽  
Central Register ◽  
Significant Difference ◽  
Observational Design

Background: Azithromycin (AZM) has been widely used in the management of Covid-19. However, the evidence on its actual effects remains disperse and difficult to apply in clinical settings. This systematic review and metanalysis summarizes the studies on the beneficial and adverse effect of AZM in patients with Covid-19. Methods: The PRISMA 2020 statement criteria were followed. Randomized controlled trials (RCTs) and observational studies comparing clinical outcomes of patients treated, and not treated, with AZM, indexed until the 5th of July 2021, were searched in PubMed, Embase, The Web of Science, Scopus, The Cochrane Central Register of Controlled Trials, and MedRXivs. We used Random-effects models to estimate pooled effect size from aggregate data. Results: The initial search produced 4950 results. Finally, 16 studies, five RCTs and 11 with an observational design, with a total of 22984 patients, were included. The metanalysis showed no difference in mortality for those treated, or not, with AZM, OR: 0.95 (0.79-1.13). There was also no significant difference for those treated, and not, with AZM in need for hospital admission or time to admission from ambulatory settings, clinical severity, need for intensive care, or adverse effects. Conclusions: These results presented in this review do not support the use of AZM in the management of Covid-19. They also show that any harm caused to the patient who received it is unlikely. Future research on treatment for patients with Covid-19 may need to focus on other drugs

scholarly journals Desenvolvimento de transtornos mentais relacionados à úlcera venosa: revisão sistemática

2019 ◽  
Vol 11 (16) ◽  
pp. e1417
Author(s):  
Adriana Souza Szpalher
Keyword(s):  
Controlled Trials ◽  
Cochrane Central Register ◽  
National Library ◽  
Electronic Library ◽  
Central Register

Objetivo: Avaliar o desenvolvimento de transtornos psicológicos relacionados à presença de úlcera venosa de perna (UVP). Métodos: revisão sistemática em julho de 2019 com metodologia de Donato H e Donato M (2019) e Recomendação PRISMA para responder à questão: há desenvolvimento de transtornos psicológicos relacionados à UVP? Incluídos estudos originais, sem delimitação temporal, em português, inglês e espanhol, nas Bases US National Library of Medicine (PubMed), Biblioteca Virtual de Saúde (BVS), The Cochrane Central Register of Controlled Trials (CENTRAL) abrangendo a Base eletrônica editora Elsevier (EMBASE), Scientific Electronic Library Online (SciELO) e Health Evidence. Resultados: A busca retornou 256 estudos, após análise completa foram excluídos 248 por não atenderem a metodologia e objetivo, resultando em 8 estudos, prevalecendo em inglês. 816 indivíduos foram avaliados, predominando como transtorno mental a depressão. Houve diversidade quanto ao Tipo de estudo. Considerações finais: há pouca produção relacionada à temática e não foi encontrada revisão sistemática. Sugerem-se estudos que aprofundem o impacto dos transtornos psicológicos na UVP, enfatizando os níveis citológico e histológico. Acredita-se que pesquisas futuras trarão reflexões acerca da importância do atendimento psicológico e psiquiátrico, associado à promoção de atividades de bem-estar e do convívio social.

scholarly journals Fluid resuscitation in paediatric burns: how do we get it right? A systematic review of the evidence

2018 ◽  
Vol 104 (3) ◽  
pp. 280-285 ◽  
Author(s):  
Christopher Stutchfield ◽  
Anna Davies ◽  
Amber Young
Keyword(s):  
Systematic Review ◽  
Fluid Resuscitation ◽  
Primary Data ◽  
Controlled Trials ◽  
Burn Shock ◽  
Cochrane Central Register ◽  
Study Protocols ◽  
Central Register ◽  
Affect Patient Outcome ◽  
Randomised Controlled

BackgroundOptimal fluid resuscitation in children with major burns is crucial to prevent or minimise burn shock and prevent complications of over-resuscitation.ObjectivesTo identify studies using endpoints to guide fluid resuscitation in children with burns, review the range of reported endpoint targets and assess whether there is evidence that targeted endpoints impact on outcome.DesignSystematic review.MethodsMedline, Embase, Cinahl and the Cochrane Central Register of Controlled Trials databases were searched with no restrictions on study design or date. Search terms combined burns, fluid resuscitation, endpoints, goal-directed therapy and related synonyms. Studies reporting primary data regarding children with burns (<16 years) and targeting fluid resuscitation endpoints were included. Data were extracted using a proforma and the results were narratively reviewed.ResultsFollowing screening of 777 unique references, 7 studies fulfilled the inclusion criteria. Four studies were exclusively paediatric. Six studies used urine output (UO) as the primary endpoint. Of these, one set a minimum UO threshold, while the remainder targeted a range from 0.5–1.0 mL/kg/hour to 2–3 mL/kg/hour. No studies compared different UO targets. Heterogeneous study protocols and outcomes precluded comparison between the UO targets. One study targeted invasive haemodynamic variables, but this did not significantly affect patient outcome.ConclusionsFew studies have researched resuscitation endpoints for children with burns. Those that have done so have investigated heterogeneous endpoints and endpoint targets. There is a need for future randomised controlled trials to identify optimal endpoints with which to target fluid resuscitation in children with burns.

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