scholarly journals Oral health in patients with chronic kidney disease

Praxis medica ◽  
2020 ◽  
Vol 49 (1-2) ◽  
pp. 35-40
Author(s):  
Radojica Stolić ◽  
Vekoslav Mitrović ◽  
Naja Suljković ◽  
Dušica Miljković-Jakšić ◽  
Aleksandra Balović ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Oral Health ◽  
Kidney Disease ◽  
Periodontal Disease ◽  
Patient Population ◽  
Periodontal Diseases ◽  
Oral Disease ◽  
Gingival Hyperplasia ◽  
Oral Diseases ◽  
The Impact

Objective: In the available literature data, there is not much information about problems of patients with end stage kidney disease in relation to oral health. Our objective was to show the importance of oral diseases for patients on hemodialysis. Data sources: In this review article, the sources of data are review articles and scientific articles in the English language published in MEDLINE database. The choice of studies was based on keywords: Chronic kidney disease, Hemodialysis, Oral health, Periodontal diseases. Results: It is assumed that almost 90% patients with chronic kidney disease manifest some symptoms of oral disease. Therefore, it is important to determine the impact of periodontal disease on the progression of kidney failure in these individuals, to evaluate inflammatory parameters in this patient population, to assess the degree of bone loss and periodontal disease index, to determine the presence of bacterial strains, paradontopathy of gingival fluid and antibody titers, to examine correlations of proinflammatory cytokines in the gingival sulcus and serum, as well as to determine the relationship between periodontal tissue and inflammatory mediators. Periodontal diseases can increase the possibility of developing chronic kidney disease by 1.5 to 2 times. These oral diseases include gingival hyperplasia, periodontitis, xerostomia, unpleasant breath, changes in the oral mucosa, malignancies, oral infections, dental abnormalities and bone lesions. Conclusion: This requires serious cooperation between nephrologists and dentists to make proper communication possible, in order to provide quality dental care for this growing patient population in accordance with new treatment strategies.

scholarly journals How oral infections can influence chronic kidney disease – a review of the literature

2020 ◽  
Vol 23 (1) ◽  
Author(s):  
Carla Cruvinel Pontes ◽  
Usuf ME Chikte
Keyword(s):  
Chronic Kidney Disease ◽  
Oral Health ◽  
Kidney Disease ◽  
Periodontal Disease ◽  
Negative Impact ◽  
The Body ◽  
Oral Disease ◽  
Oral Diseases ◽  
Oral Infections ◽  
Source Of Infection

A healthy mouth is necessary for optimal health and quality of life. However, oral health is often compromised in adults with chronic kidney disease (CKD). The aim of this review was to present the scientific foundations behind the connection between oral diseases and chronic kidney disease (CKD) in adults, discuss common oral conditions and their systemic effects, investigate biological pathways through which oral infections affect the body and provide guidelines for physicians/nephrologists. Prevalence of oral disease is increased in CKD, including periodontal disease, oral mucosal lesions, edentulousness, xerostomia, gingival overgrowth in immunosuppressed patients and potentially caries. There is moderate to strong evidence to support a negative impact of oral infections in CKD, particularly periodontal disease, with systemic inflammation, bacteraemia of oral origin, endothelial function and gut dysbiosis being potential pathways for this interaction. Poor oral health can be a hidden source of infection and has been associated with increased mortality in CKD patients. Elimination of potential foci for oral infections is crucial before renal transplantation. Frequent dental monitoring is crucial for these patients and should be part of a multidisciplinary approach to manage CKD, with special attention to end-stage kidney disease.

scholarly journals Relationship between dental and periodontal health status and the salivary microbiome: bacterial diversity, co-occurrence networks and predictive models

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Relvas ◽  
A. Regueira-Iglesias ◽  
C. Balsa-Castro ◽  
F. Salazar ◽  
J. J. Pacheco ◽  
...  
Keyword(s):  
Oral Health ◽  
Periodontal Disease ◽  
Bacterial Diversity ◽  
Predictive Models ◽  
Oral Disease ◽  
Rrna Gene ◽  
Convenience Sample ◽  
Core Microbiome ◽  
Rdna Sequencing ◽  
The Impact

AbstractThe present study used 16S rRNA gene amplicon sequencing to assess the impact on salivary microbiome of different grades of dental and periodontal disease and the combination of both (hereinafter referred to as oral disease), in terms of bacterial diversity, co-occurrence network patterns and predictive models. Our scale of overall oral health was used to produce a convenience sample of 81 patients from 270 who were initially recruited. Saliva samples were collected from each participant. Sequencing was performed in Illumina MiSeq with 2 × 300 bp reads, while the raw reads were processed according to the Mothur pipeline. The statistical analysis of the 16S rDNA sequencing data at the species level was conducted using the phyloseq, DESeq2, Microbiome, SpiecEasi, igraph, MixOmics packages. The simultaneous presence of dental and periodontal pathology has a potentiating effect on the richness and diversity of the salivary microbiota. The structure of the bacterial community in oral health differs from that present in dental, periodontal or oral disease, especially in high grades. Supragingival dental parameters influence the microbiota’s abundance more than subgingival periodontal parameters, with the former making a greater contribution to the impact that oral health has on the salivary microbiome. The possible keystone OTUs are different in the oral health and disease, and even these vary between dental and periodontal disease: half of them belongs to the core microbiome and are independent of the abundance parameters. The salivary microbiome, involving a considerable number of OTUs, shows an excellent discriminatory potential for distinguishing different grades of dental, periodontal or oral disease; considering the number of predictive OTUs, the best model is that which predicts the combined dental and periodontal status.

Oral Health and Nutrition

2020 ◽  
Author(s):  
Carole. A. Palmer ◽  
Zhangmuge Cheng
Keyword(s):  
Oral Health ◽  
Dental Caries ◽  
Periodontal Diseases ◽  
Oral Disease ◽  
Oral Diseases ◽  
Oral Infections ◽  
Surgeon General ◽  
Optimal Health ◽  
Health And Disease ◽  
Oral Conditions

Oral diseases are among the most prevalent diseases affecting global health. In his report on the crisis in oral disease in America, the Surgeon General warned that one cannot be truly healthy without oral health. Oral health means freedom from all oral health problems; tooth decay (dental caries), periodontal diseases, tooth loss, oral-facial pain, oral cancer and the effects of its treatment, oral infections, craniofacial birth defects and more. The relationships between oral conditions and systemic health and disease are many and synergistic, and most involve dietary and/or systemic nutritional factors. Diet and nutrition can play important roles in the etiology, prevention, and/or management of oral conditions, as they do in overall health and disease. Today, all health professionals and educators need to be aware of and consider oral issues and their possible diet/nutritional implications as a component of optimal health care and education. This review article provides a brief overview of how diet and nutrition impact and are impacted by oral conditions, and offers general guidelines and resources for providing meaningful interventions throughout the life cycle. This review contains 3 figures, 3 tables, and 57 references Key Words: biofilm, cariogenic, dental caries, dental plaque, ECC-early childhood caries, lactobacillus, mucositis, non-cariogenic, periodontal disease, Streptococcus mutans

scholarly journals Individuals’ quality of life in periodontal maintenance therapy - critical literature review.

2018 ◽  
Vol 7 (6) ◽  
pp. 263-270
Author(s):  
Amanda Almeida Costa ◽  
◽  
Fernando Oliveira Costa ◽  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Periodontal Disease ◽  
Maintenance Therapy ◽  
Tooth Loss ◽  
Health Impact ◽  
Oral Diseases ◽  
Periodontal Maintenance ◽  
The Impact

Abstract: Oral health is an integral part of an individual’s general health, interfering with all dimensions of life: functional, aesthetic, psychological, social, physical, nutritional, and even psychosocial. Hence oral health is directly related to quality of life. Periodontitis is one of the most prevalent oral diseases and one of the major causes of tooth loss, impacting negatively on self-reported individuals’ quality of life. Periodontal maintenance therapy aims to effectively minimize the recurrence of periodontal disease, as well as the incidence of tooth loss. In periodontal literature, studies associated with quality of life indicators, presented in the form of questionnaires aimed at measuring the impact of periodontitis and tooth loss on self-reported individual’s quality of life, highlight the "Oral Impacts on Daily Performance" (OIDP) and "Oral Health Impact Profile" (OHIP). As such, this study presents a critical review of the literature and describes the impact of periodontal disease and tooth loss on the quality of life of patients undergoing periodontal maintenance therapy.

Prevalence of oral diseases in dogs in Tirana urban area

2016 ◽  
Author(s):  
Haxhi Allmuca ◽  
Péllumb Zalla ◽  
Egon Andoni ◽  
Brunilda Mazari
Keyword(s):  
Periodontal Disease ◽  
Small Animal ◽  
Oral Disease ◽  
Gingival Hyperplasia ◽  
Dental Calculus ◽  
Oral Diseases ◽  
High Prevalence ◽  
Dental Diseases ◽  
The Right ◽  
Veterinary Hospital

The purpose of this study was to determine the frequency of oral diseases in dogs examined at the Small Animal Veterinary Hospital during 2013 - 2014. The dogs underwent a special control for diseases of oral cavity. Site specifications and severity of dental diseases were assessed using modified indexing systems. A total number of 776 dogs, presented at a private Tirana/Albania urban veterinary hospital for different reasons, during this period were analyzed. Analysis by oral disease type revealed 692 dogs or 89.1% dent-gingival disorders. Of these animals, 441 (56.8%) of 776 dogs had periodontal disease; 468 (60.3%) had dental calculus; 241 (31.0%) had teeth loss and 50 (6.4%) had abnormal attrition. Two cases of dogs suffering from tumours, one case with dental caries, two cases with the enamel hypoplasia and one case with gingival hyperplasia, were also observed. Data from this study showed that periodontitis and dental calculus are among the most common diseases prevalent in dogs. There were also observed changes in the deposit of calculus between the upper and lower jaw; with the most calculus deposits observed in the upper jaw. No differences were observed between the right side and the left side of the jaw. Dental calculus index was almost the same between the right side and left side. Frequency of periodontal changes and the degree of inflammation increased with an increase in the age of the dog. Dental calculus was observed at an earlier age in small breeds of dogs. Dental calculus index was lower in large dog breeds compared to the small dog breeds and increased with age. Results of the study showed a high prevalence of oral diseases in dogs and confirmed that periodontal disease is the most common oral disease in dogs.

scholarly journals Impact of Periodontal Diseases on Health-Related Quality of Life of Users of the Brazilian Unified Health System

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Pamella Valente Palma ◽  
Paula Liparini Caetano ◽  
Isabel Cristina Gonçalves Leite
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Periodontal Disease ◽  
Periodontal Diseases ◽  
Health Related Quality ◽  
Unified Health System ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Objective.This study assessed the impact of periodontal diseases on health-related quality of life of adult users of the Brazilian Unified Health System.Study Design.A cross-sectional study was conducted on an outpatient basis. The sample included 151 adults treated in the Periodontics section at Dental Specialty Centres of Juiz de Fora (Minas Gerais, Brazil). TheOral Health Impact Profile(OHIP-14) measured the impact of periodontal disease on quality of life. Participants were interviewed to obtain self-perception of general and oral health and socioeconomic data, and dental records were consulted to obtain periodontal status data. The values of central tendency of the OHIP-14 were compared with socioeconomic, demographic, and self-reported health predictors using nonparametric tests. The final analysis was performed using multiple linear regressions.Results.The results showed that psychological discomfort and physical disability exhibited a negative impact. The following variables can explain approximately 27% of the impact of oral health conditions on health-related quality of life in this group: periodontal disease, self-perceived oral health, and the need to use or replace dental prosthesis.Conclusion.The need for prosthetic rehabilitation and worse periodontal status are associated with health-related quality of life, which can be predicted by the self-perception of health.

scholarly journals Microbiota populations in supragingival plaque, subgingival plaque, and saliva habitats of adult dogs

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Patrícia M. Oba ◽  
Meredith Q. Carroll ◽  
Celeste Alexander ◽  
Helen Valentine ◽  
Amy J. Somrak ◽  
...  
Keyword(s):  
Oral Health ◽  
Oral Cavity ◽  
Periodontal Disease ◽  
Bacterial Species ◽  
Oral Disease ◽  
Oral Microbiota ◽  
Subgingival Plaque ◽  
Oral Diseases ◽  
Supragingival Plaque

Abstract Background Oral diseases are common in dogs, with microbiota playing a prominent role in the disease process. Oral cavity habitats harbor unique microbiota populations that have relevance to health and disease. Despite their importance, the canine oral cavity microbial habitats have been poorly studied. The objectives of this study were to (1) characterize the oral microbiota of different habitats of dogs and (2) correlate oral health scores with bacterial taxa and identify what sites may be good options for understanding the role of microbiota in oral diseases. We used next-generation sequencing to characterize the salivary (SAL), subgingival (SUB), and supragingival (SUP) microbial habitats of 26 healthy adult female Beagle dogs (4.0 ± 1.2 year old) and identify taxa associated with periodontal disease indices. Results Bacterial species richness was highest for SAL, moderate for SUB, and lowest for SUP samples (p < 0.001). Unweighted and weighted principal coordinates plots showed clustering by habitat, with SAL and SUP samples being the most different from one another. Bacteroidetes, Proteobacteria, Firmicutes, Fusobacteria, Actinobacteria, and Spirochaetes were the predominant phyla in all habitats. Paludibacter, Filifactor, Peptostreptococcus, Fusibacter, Anaerovorax, Fusobacterium, Leptotrichia, Desulfomicrobium, and TG5 were enriched in SUB samples, while Actinomyces, Corynebacterium, Leucobacter, Euzebya, Capnocytophaga, Bergeyella, Lautropia, Lampropedia, Desulfobulbus, Enhydrobacter, and Moraxella were enriched in SUP samples. Prevotella, SHD-231, Helcococcus, Treponema, and Acholeplasma were enriched in SAL samples. p-75-a5, Arcobacter, and Pasteurella were diminished in SUB samples. Porphyromonas, Peptococcus, Parvimonas, and Campylobacter were diminished in SUP samples, while Tannerella, Proteocalla, Schwartzia, and Neisseria were diminished in SAL samples. Actinomyces, Corynebacterium, Capnocytophaga, Leptotrichia, and Neisseria were associated with higher oral health scores (worsened health) in plaque samples. Conclusions Our results demonstrate the differences that exist among canine salivary, subgingival plaque and supragingival plaque habitats. Salivary samples do not require sedation and are easy to collect, but do not accurately represent the plaque populations that are most important to oral disease. Plaque Actinomyces, Corynebacterium, Capnocytophaga, Leptotrichia, and Neisseria were associated with higher (worse) oral health scores. Future studies analyzing samples from progressive disease stages are needed to validate these results and understand the role of bacteria in periodontal disease development.

scholarly journals Pathological Characteristics of Periodontal Disease in Patients with Chronic Kidney Disease and Kidney Transplantation

2019 ◽  
Vol 20 (14) ◽  
pp. 3413 ◽  
Author(s):  
Mineaki Kitamura ◽  
Yasushi Mochizuki ◽  
Yasuyoshi Miyata ◽  
Yoko Obata ◽  
Kensuke Mitsunari ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Transplantation ◽  
Kidney Disease ◽  
Periodontal Disease ◽  
Immunosuppressive Therapy ◽  
Kidney Allograft ◽  
Periodontal Tissues ◽  
Pathological Conditions ◽  
Allograft Function ◽  
The Impact

Chronic kidney disease (CKD) is recognized as an irreversible reduction of functional nephrons and leads to an increased risk of various pathological conditions, including cardiovascular disease and neurological disorders, such as coronary artery calcification, hypertension, and stroke. In addition, CKD patients have impaired immunity against bacteria and viruses. Conversely, kidney transplantation (KT) is performed for patients with end-stage renal disease as a renal replacement therapy. Although kidney function is almost normalized by KT, immunosuppressive therapy is essential to maintain kidney allograft function and to prevent rejection. However, these patients are more susceptible to infection due to the immunosuppressive therapy required to maintain kidney allograft function. Thus, both CKD and KT present disadvantages in terms of suppression of immune function. Periodontal disease is defined as a chronic infection and inflammation of oral and periodontal tissues. Periodontal disease is characterized by the destruction of connective tissues of the periodontium and alveolar bone, which may lead to not only local symptoms but also systemic diseases, such as cardiovascular diseases, diabetes, liver disease, chronic obstructive pulmonary disease, and several types of cancer. In addition, the prevalence and severity of periodontal disease are significantly associated with mortality. Many researchers pay special attention to the pathological roles and clinical impact of periodontal disease in patients with CKD or KT. In this review, we provide information regarding important modulators of periodontal disease to better understand the relationship between periodontal disease and CKD and/or KT. Furthermore; we evaluate the impact of periodontal disease on various pathological conditions in patients with CKD and KT. Moreover, pathogens of periodontal disease common to CKD and KT are also discussed. Finally, we examine the importance of periodontal care in these patients. Thus, this review provides a comprehensive overview of the pathological roles and clinical significance of periodontal disease in patients with CKD and KT.

scholarly journals Vitamin D Receptor Gene Polymorphisms and Cigarette Smoking Impact on Oral Health: A Case-Control Study

2020 ◽  
Vol 17 (9) ◽  
pp. 3192
Author(s):  
Aleksandra Suchanecka ◽  
Krzysztof Chmielowiec ◽  
Jolanta Chmielowiec ◽  
Grzegorz Trybek ◽  
Jolanta Masiak ◽  
...  
Keyword(s):  
Vitamin D ◽  
Oral Health ◽  
Vitamin D Receptor ◽  
Smoking Status ◽  
Periodontal Diseases ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Gingival Index ◽  
Oral Diseases ◽  
The Impact

Periodontal diseases are multiperspective problems resulting from numerous and diverse exposures that influence the process of initiation or progression of disease. The negative influence of tobacco smoking on oral health is well documented. The aim of the study was to analyze three SNPs in vitamin D receptor gene—rs7975232 (ApaI), rs2228570 (FokI) and rs1544410 (BsmI)—combined with oral health assessment—pH, gingival index, dry mouth, periodontitis, dry socket, redness of oral cavity mucosa, leukoplakia—in a group of cigarette smokers and in non-smokers. Moreover, the possibility of interactions between these polymorphisms and smoking was examined. When comparing the smokers and non-smokers groups, we noticed that rs1544410 heterozygotes were significantly more frequent in the first group, and for the second, both homozygotes were more frequent. Additionally, we observed the impact of interaction between the rs7975232 genotype and smoking status on gingival index. Current smoking was also associated with all analyzed oral health measures except for leucoplakia. Correlation between pH and age in both smokers and non-smokers was also present. Results of our analysis indicate that in our study group lifestyle and aging were leading factors associated with worse oral health status. However, the impact of genetic variants, and also the impact of their interaction with smoking on analyzed parameters was also visible. These results show great possibilities for all levels of prevention of oral diseases by means of education based on evidence-based medicine, but also for incorporating genetic testing and early interventions into this process for predisposed individuals.

scholarly journals Evaluation of the impact of oral health on the quality of life of patients with chronic kidney disease (CKD)

2019 ◽  
Vol 5 (12) ◽  
pp. 31854-31864
Author(s):  
Dyenily Alessi Sloboda ◽  
Jeanny Franciela Kos Moleta ◽  
Lauryellen Aparecida Padilha ◽  
Paula Motta Santos ◽  
Fábio André Santos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Oral Health ◽  
Kidney Disease ◽  
The Impact
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