Market access – An essential investment before drug launch

1969 ◽  
Vol 16 (3) ◽  
Author(s):  
Sean McGrath
Keyword(s):  
Market Access ◽  
New Product ◽  
Decision Makers ◽  
Good Time ◽  
Local Health ◽  
Local Health Care ◽  
Local Decision ◽  
Advance Information ◽  
The Impact ◽  
Local Decision Makers

Before introducing a new pharmaceutical/biopharmaceutical agent into clinical practice, local decision makers need to consider not only the costs and benefits of the product, but also the impact that it will have on local health-care priorities and on the manner in which services are delivered. Its use is likely to require updated protocols, new patient information, staff training and changes to the manner in which clinics are organised – all of which can take many months to develop and implement. Hence, timely introduction of a new product relies on the delivery of advance information via a carefully planned market access strategy. Ideally, local decision makers need to receive initial notification of the likely impact of a product at least 18 months before its launch date, with follow-up communications at intervals thereafter. Failure to devise and fund a market access strategy in good time can reduce the company's return on its product. More important, patients may have to wait for access to the new product, and there is a potential for inequality of care when the introduction of a drug is delayed in some areas and not in others.

scholarly journals Reducing inequality in avoidable emergency admissions: Case studies of local health care systems in England using a realist approach

2021 ◽  
pp. 135581962110216
Author(s):  
John Ford ◽  
Julia Knight ◽  
John Brittain ◽  
Chris Bentley ◽  
Sarah Sowden ◽  
...  
Keyword(s):  
Health Care ◽  
Case Studies ◽  
Health Care Systems ◽  
Decision Makers ◽  
Local Health ◽  
Emergency Admissions ◽  
Local Health Care ◽  
Local Decision ◽  
Care Systems ◽  
Local Decision Makers

Objective People in disadvantaged areas are more likely to have an avoidable emergency hospital admission. Socio-economic inequality in avoidable emergency hospital admissions is monitored in England. Our aim was to inform local health care purchasing and planning by identifying recent health care system changes (or other factors), as reported by local health system leaders, that might explain narrowing or widening trends. Methods Case studies were undertaken in one pilot and at five geographically distinct local health care systems (Clinical Commissioning Groups, CCGs), identified as having consistently increasing or decreasing inequality. Local settings were explored through discussions with CCG officials and stakeholders to identify potential local determinants. Data were analysed using a realist evaluation approach to generate context-mechanism-outcome (CMO) configurations. Results Of the five geographically distinct CCGs, two had narrowing inequality, two widening, and one narrowing inequality, which widened during the project. None of the CCGs had designed a large-scale package of service changes with the explicit aim of reducing socio-economic inequality in avoidable emergency admissions, and local decision makers were unfamiliar with their own trends. Potential primary and community care determinants included: workforce, case finding and exclusion, proactive care co-ordination for patients with complex needs, and access and quality. Potential commissioning determinants included: data use and incentives, and targeting of services. Other potential determinants included changes in care home services, national A&E targets, and wider issues - such as public services financial constraints, residential gentrification, and health care expectations. Conclusions We did not find any bespoke initiatives that explained the inequality trends. The trends were more likely due to an interplay of multiple health care and wider system factors. Local decision makers need greater awareness, understanding and support to interpret, use and act upon inequality indicators. They are unlikely to find simple, cheap interventions to reduce inequalities in avoidable emergency admissions. Rather, long-term multifaceted interventions are required that embed inequality considerations into mainstream decision making.

Evaluation of Toll Options with Quick-Response Analysis Tools: Case Study of the Capital Beltway

2003 ◽  
Vol 1839 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Patrick DeCorla-Souza
Keyword(s):  
Decision Makers ◽  
Response Analysis ◽  
The Public ◽  
Analysis Tools ◽  
Project Construction ◽  
Local Decision ◽  
Decision Making Processes ◽  
The Impact ◽  
Local Decision Makers

Analysis tools in current use in transportation decision-making processes are not well suited for evaluating toll highway alternatives against more traditional free highway alternatives. How existing analysis tools might be used in evaluating toll options was examined. A case study demonstrates that relatively simple analytical procedures may be used to estimate the impact of pricing alternatives and to generate information for use by local decision makers. The case study also demonstrates that pricing alternatives often can accomplish the purpose of a major highway project more efficiently and more effectively than conventional alternatives that exclude pricing, while generating revenue to support bonds for project construction or to fund improved transit and paratransit services. With toll revenue to back bonds, project delays due to constrained funding can be avoided, and the public can be provided with superior mobility earlier and at lower public cost.

Single Conversations Expand Practitioners’ Use of Research: Evidence from a Field Experiment

2021 ◽  
pp. 1-6
Author(s):  
Adam Seth Levine
Keyword(s):  
Field Experiment ◽  
Research Evidence ◽  
Decision Makers ◽  
Wide Audience ◽  
Substantial Impact ◽  
Interactive Strategies ◽  
Local Decision ◽  
The Impact ◽  
Local Decision Makers ◽  
Use Of Research

ABSTRACT Many people seek to increase practitioners’ use of research evidence in decision making. Two common strategies are dissemination and interaction. Dissemination can reach a wide audience at once, yet interactive strategies can be beneficial because they entail back-and-forth conversations to clarify how research evidence applies in a particular context. To date, however, we lack much direct evidence of the impact of interaction beyond dissemination. Partnering with an international sustainability-oriented NGO, I conducted a field experiment to test the impact of an interactive strategy (i.e., a single conversation) on practitioners’ use of research evidence in a pending decision. I find that the conversation had a substantial impact on research use relative to only receiving disseminated materials, which likely was due to increased self-efficacy. I also provide practical guidance on how researchers can apply this finding close to home by strengthening linkages with local decision makers.

scholarly journals International and regional variation in the prevalence of common mental disorders: do we need more surveys?

2004 ◽  
Vol 184 (4) ◽  
pp. 289-290 ◽  
Author(s):  
Scott Weich ◽  
Ricardo Araya
Keyword(s):  
Mental Disorders ◽  
Regional Variation ◽  
Common Mental Disorders ◽  
Psychiatric Morbidity ◽  
Epidemiological Survey ◽  
Decision Makers ◽  
Local Decision ◽  
Local Decision Makers ◽  
Geographical Locations

Vicente and his colleagues present admirably concise findings from a large epidemiological survey of non-psychotic psychiatric morbidity in four different geographical locations in Chile (Vicente et al, 2004, this issue). Without gainsaying the importance of psychiatric morbidity in that country, many readers, including local decision-makers, may find it difficult to assimilate these results.

scholarly journals Coroners' records on suicide mortality in Montréal: limitations and implications in suicide prevention strategies

2014 ◽  
Vol 34 (1) ◽  
pp. 23-29 ◽  
Author(s):  
J Houle ◽  
C Guillou-Ouellette
Keyword(s):  
Suicide Prevention ◽  
Suicide Attempts ◽  
Decision Makers ◽  
The Other ◽  
Suicide Mortality ◽  
Prevention Strategies ◽  
The People ◽  
Local Decision ◽  
Local Decision Makers ◽  
Very High

Introduction In Montréal, the characteristics of suicide cases may vary between different areas. The information collected by coroners during their investigations of suicides could be used to support local suicide-prevention planning actions. Methods This study analyzes all coroners' records on suicide in Montréal from 2007 to 2009 to 1. determine the usefulness of the data available; 2. develop a profile of cases; 3. examine local differences by comparing two areas, one with the highest suicide rate and the other with the lowest. Results The data collected revealed the lack of a systematic, standardized procedure for recording information about deaths by suicide. The rates of missing data varied, but were very high for antecedents of suicide attempts and recent events that could have precipitated the suicide. We observed differences in the characteristics of suicide cases according to area of residence. Conclusion By adopting a standardized procedure for collecting information on cases of suicide, coroners could provide local decision makers with a more accurate portrait of the people who die by suicide in their area. Local adjustments may improve suicide-prevention strategies.

Entrepreneurial ecosystems: a systematic review

2018 ◽  
Vol 12 (4) ◽  
pp. 545-564 ◽  
Author(s):  
Parisa Maroufkhani ◽  
Ralf Wagner ◽  
Wan Khairuzzaman Wan Ismail
Keyword(s):  
Systematic Review ◽  
Information Exchange ◽  
Decision Makers ◽  
Content Type ◽  
Entrepreneurial Ecosystems ◽  
Science Index ◽  
Local Decision ◽  
State Of Research ◽  
Local Decision Makers ◽  
Practical Implications

PurposeThe literature on entrepreneurial ecosystems is fragmented, and yet, no studies have paid attention to integrating the available studies. The purpose of this study is to provide a systematic review of contributions related to entrepreneurial ecosystems.Design/methodology/approachThis literature review evaluates studies that are covered in the Web of Science index.FindingsIn addition to the recent state of research (covering industries, geographical scopes, methodologies, etc.), this study provides an extension of Isenberg’s (2011) model of entrepreneurial ecosystems.Research limitations/implicationsA new avenue arises for both conceptual and empirical research by emphasizing crowdsourcing as a contributing element for the entrepreneurial ecosystem. Future studies can evaluate the effectiveness of different types of crowdsourcing profoundly to make sure whether creating a promising ecosystem all types of crowdsourcing have a similar value or impact.Practical implicationsFor public policy and local decision-makers, both collaboration opportunities and interaction interfaces between the stakeholders of the entrepreneurial need to be reconsidered in the design of entrepreneurial ecosystems.Social implicationsHigher degrees of collaboration, information exchange and innovation are likely to yield favorable entrepreneurship environments.Originality/valueNovelty of this study arises from integrating crowdsourcing theory in the systematic review of entrepreneurial ecosystems.

scholarly journals Assessing subsoil void hazards along a road system using H/V measurements, ERTs and IPTs to support local decision makers

2018 ◽  
Vol 16 (3) ◽  
pp. 282-297 ◽  
Author(s):  
Veronica Pazzi ◽  
Mattia Ceccatelli ◽  
Teresa Gracchi ◽  
Elena Benedetta Masi ◽  
Riccardo Fanti
Keyword(s):  
Decision Makers ◽  
Local Decision ◽  
Local Decision Makers ◽  
Road System
Sign in / Sign up

Export Citation Format

Share Document