Stanford's licensing and equity practices with biotechnology companies

2005 ◽  
Vol 11 (4) ◽  
Author(s):  
Kirsten Leute
Keyword(s):  
Intellectual Property ◽  
Early Stage ◽  
Financial Resources ◽  
Technology Licensing ◽  
Start Up ◽  
History Of ◽  
Biotechnology Companies ◽  
Rate Of Success ◽  
Start Ups

Stanford University's Office of Technology Licensing (OTL) has a long history of licensing technologies to biotechnology start-up companies. This paper presents (1) examples of how the OTL works with biotechnology start-ups to negotiate licence agreements for Stanford-owned intellectual property, taking into account a new company's scarce financial resources and needs but their large intellectual property appetite; and (2) an analysis of the rate of success of biotechnology companies emerging from Stanford based on information obtained from the equity records at Stanford's OTL. OTL started taking equity more often in start-up companies in the mid-1990s and generally takes equity as part of most exclusive licences to early-stage companies.

Start-Ups and Spin-Offs in Biotechnology Sector in Poland

Biotechnology ◽  
2019 ◽  
pp. 1293-1321
Author(s):  
Anna Białek-Jaworska ◽  
Renata Gabryelczyk
Keyword(s):  
Business Models ◽  
Stock Exchange ◽  
Early Stage ◽  
Global Strategy ◽  
Third Party ◽  
Start Up ◽  
Warsaw Stock Exchange ◽  
Business Line ◽  
Definition Of ◽  
Start Ups

This chapter concerns the subject of research-developmental activity of biotech spin-offs in Poland with particular reference to their strategy, determinants of their development and determinants of their financial standing. In the chapter, the authors analyse the determinants of biotech spin-offs and start-ups development in Poland in the light of the research commercialisation cooperation on the universities-business line. The literature overview contains the definition of a process for the commercialisation of the results of research and development (R&D) activity and components of companies' business models. The chapter defines key activities in the development of business models in the context of the commercialisation process and the life cycle of the company, especially at the start up and early stage. Quality-quantitative analysis includes the business models of seven biotechnology spin-offs traded on the alternative market of the Warsaw Stock Exchange, especially the structure of their intellectual capital, R&D expenses in relation to received subsides and grants, third-party shares in start up equity, and the ability to realise the “Go Global” strategy.

scholarly journals The early growth of start-ups: innovation matters. Evidence from Italy

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Raffaele Fiorentino ◽  
Sergio Longobardi ◽  
Alessandro Scaletti
Keyword(s):  
Propensity Score ◽  
Propensity Score Matching ◽  
Firm Growth ◽  
Ad Hoc ◽  
Early Stage ◽  
New Ventures ◽  
Objective Measure ◽  
Content Type ◽  
Start Up ◽  
Start Ups

PurposeDespite the relevance of innovation in entrepreneurship literature, empirical research on the innovation-performance relationship in start-ups is underdeveloped and shows controversial results. To bridge this gap, the aim of this paper is to investigate the role of innovativeness on new venture performance in the early stage of the life cycle.Design/methodology/approachRegression modelling and propensity score matching are used to reveal systematic differences in growth between innovative start-ups (ISUPs) and non-innovative start-ups. We use an ad hoc dataset obtained through merging the financial database AIDA with data from administrative sources (Italian Chambers of Commerce and the Italian Ministry for Economic Development).FindingsThe results show that differences in growth can be explained by the different levels of innovativeness in new ventures. Moreover, unlike in prior studies, the innovation inputs matter more than innovation outputs. Indeed, the results support the idea that innovation policies can contribute to maximising the potential of start-ups.Practical implicationsThe findings provide suggestions for policy makers and entrepreneurs to help firms configure ex ante appropriate actions to support the growth of new ventures in the start-up stage.Originality/valueThis study is the first to use the new objective measure of start-up innovation, available from the Italian LD 221 register. Second, different types of innovation are investigated as antecedents of firm growth. Third, we employ propensity score matching, which favours revealing systematic differences in growth between ISUPs and non-innovative start-ups. Fourth, the results of our study are the first to offer evidence on the effectiveness of the new Italian sustaining ISUPs policy.

scholarly journals Design practices for strategic innovation in start-ups

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Daphna GLAUBERT ◽  
Zarina CHARLESWORTH ◽  
Nathalie NYFFELER ◽  
Luc BERGERON ◽  
Luc BERGERON
Keyword(s):  
Early Stage ◽  
Self Report ◽  
Initial Development ◽  
Design Practices ◽  
Strategic Innovation ◽  
Stage Of Development ◽  
Start Up ◽  
Product Service ◽  
Working Together ◽  
Start Ups

This paper looks at the use of design practices in start-up firms for the creation of strategic advantage through product/service innovation. Start-ups face non-negligible challenges during the early-stage of development. The research questions examined to what extent design practices can provide the leverage needed to face these challenges. A 4-day Innovation by Design Challenge workshop provided the field for the research carried out. Participants were start-up firms each working together with two designers to form six teams. Methods used included: observation for the mapping of team activities; a short self-report questionnaire and; pre- and post-workshop semi-directed interviews with the start-ups. The findings support the idea that design practice integration into the initial development of a start-up can indeed provide a lever for success and provide the start-up with the strategic vision needed to go through the early-stage and bring their products/services to market successfully.

The Corporate Social Network (CSN) in SME's

2017 ◽  
pp. 33-52
Author(s):  
Isabelle Choquet ◽  
Jacques Folon
Keyword(s):  
Social Networks ◽  
Social Network ◽  
Knowledge Sharing ◽  
Collective Intelligence ◽  
Early Stage ◽  
Efficient Tool ◽  
Start Up ◽  
The Creation ◽  
Corporate Social ◽  
Start Ups

The authors intend to demonstrate that corporate social networks (CSN) are a very efficient tool for SME's and start-ups, since their early launch. They will immediately create an interactive structure and a culture of collective intelligence. The chapter aims at revealing how SMEs or start-ups are able to capture the opportunities provided by CSNs, perceived as proximity social networks. The research investigates if the use of CSN at the launch of the SME promotes the development of a collective intelligence culture, but also if several CSN may coexist within the same structure according to the needs encountered: “above-the-flow” approach (dialogue, exchanges) or “in the flow” approach (integration of workflow and document). The authors strongly believe that CSN has to be introduced by a web entrepreneur at the early stage of creation of his start-up, because it supports the scaling of the business, allowing the creation of a knowledge sharing culture, making the knowledge available inside the company.

Journey's end: a dynamic framework of entrepreneurial processes and capitals relating to early stage business exit

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Richard Hanage ◽  
Pekka Stenholm ◽  
Jonathan M. Scott ◽  
Mark A.P. Davies
Keyword(s):  
Case Studies ◽  
Early Stage ◽  
Theory Building ◽  
Cross Sectional ◽  
Content Type ◽  
Dynamic Framework ◽  
Longitudinal Dynamic ◽  
Start Up ◽  
New Business ◽  
Start Ups

PurposeThe purpose of this paper is to respond to the call by McMullen and Dimov (2013) for a clearer understanding of entrepreneurial journeys by investigating the entrepreneurial capitals and micro-processes of seven young early stage entrepreneurs who all exited their businesses within 3 years of start-up.Design/methodology/approachThe authors analysed empirical data from concurrent in-depth interviews which generated rich longitudinal case studies. Theory-building then led to a proposed “Longitudinal Dynamic Process Framework” of entrepreneurial goals, processes and capitals.FindingsThe framework builds on prior studies by integrating entrepreneurial processes and decisions into two feedback loops based on continuous review and learning. It thereby enhances understanding of the dynamics of new business development and unfolds the early stage ventures entrepreneurs' business exits.Research limitations/implicationsThe findings are based on a small purposive sample. However, the main implication for research and theory is showing how the entrepreneurial capitals are dynamic and influenced by entrepreneurs' environment, and also separating entrepreneurs' personal issues from their business issues.Practical implicationsThe findings challenge some assumptions of policymakers and offer new insights for practitioners and early stage entrepreneurs. These include having more realistic case-studies of the entrepreneurial journey, recognizing the need to be agile and tenacious to cope with challenges, understanding how capitals can interact in complementary ways and that entrepreneurial processes can be used to leverage them at appropriate stages of the start-ups.Originality/valueThe concurrent longitudinal analysis and theory-building complements extant cross-sectional studies by identifying and analysing the detailed processes of actual business start-ups and exits. The proposed framework thereby adds coherence to earlier studies and helps to explain early stage entrepreneurial development, transformation of capitals and business exit.

Achieving and Sustaining New Knowledge Development in High-Expectation Start-ups

2010 ◽  
Vol 24 (1) ◽  
pp. 47-53
Author(s):  
Diego Matricano
Keyword(s):  
Competitive Advantage ◽  
Early Stage ◽  
High Growth ◽  
Knowledge Development ◽  
High Expectation ◽  
Knowledge Based ◽  
Start Up ◽  
New Knowledge ◽  
Start Ups

In markets characterized by strong competition, new knowledge and new knowledge development are generally recognized as the key means for an enterprise to gain competitive advantage. This knowledge-based competitive advantage is critical for all commercial ventures, but is especially so for high-expectation start-ups (technology-based ventures anticipating high growth rates). Even though the organizational processes of a start-up are still under development, the success of new knowledge development is affected by three critical factors – the structure of the enterprise, the organizational technology and the knowledge promoters. An analysis of these factors suggests that the role of the knowledge promoter is the key determinant of knowledge development success in the case of early-stage high-expectation start-ups.

Early stage and seed financing for biotechnology start-ups: A UK perspective

10.5912/jcb33 ◽  
1969 ◽  
Vol 9 (3) ◽  
Author(s):  
George Whitehead
Keyword(s):  
Final Section ◽  
Early Stage ◽  
Investment Opportunity ◽  
Biotechnology Companies ◽  
The Right ◽  
Start Ups

It is a tough climate in which to be raising early stage investment but there is funding available for the very best of British biotechnology. This report outlines several sources of funding that the author has found most relevant to early stage biotechnology companies. The competition for the limited funds is harsh so it is vital that biotechnology entrepreneurs choose the right sources of funding and approach them in the right way. The final section briefly outlines how companies can 'tilt the balance' in their favour and learn to move from just being scientifically convincing to becoming a commercially convincing investment opportunity.

‘Let’s Move on, Please’: Trust and Employment Relations in Early-stage Start-ups

2020 ◽  
Vol 6 (1) ◽  
pp. 182-194
Author(s):  
João Vasco Coelho
Keyword(s):  
Social Relations ◽  
Early Stage ◽  
Public Funding ◽  
Specific Interaction ◽  
Observation Data ◽  
Employment Relations ◽  
Employment Relation ◽  
Organisational Form ◽  
Start Up ◽  
Start Ups

In Portugal, an evolving start-up hype has been promoted in recent years, presenting the country as an emergent European entrepreneurial hub, a rising start-up nation. In this context, less laudatory perspectives, focused on analysing labour relations or employment creation effects, are scarce or not particularly visible. In order to address this specific analytical dimension, this article conceives a start-up as a temporary organisational form, arraying temporariness not only as an organisational attribute, but also as a specific interaction condition that moulds employment relations established between start-uppers and entrepreneurs. Analytical work is anchored in in-depth interviews and direct observation data, collected during a 12-month longitudinal study, carried out in one of the most successful start-ups created or operating in Portugal. A narrative is used as an empirical illustration of observed temporariness effects and three employment relation-specific attributes are discussed as aspects that should be inform public funding endorsement decisions: the prevalence of task-focus managerial arrangements; low levels of trust and institutionalised reciprocity; short-lived social relations and conflict deprioritisation.

scholarly journals From the Idea of Start-Up to Setting-Up Unicorn-Company

2021 ◽  
pp. 201-206
Author(s):  
E. Yu. Kulakova ◽  
G. M. Magomedova ◽  
A. A. Ivanov
Keyword(s):  
Business Activity ◽  
Start Up ◽  
History Of ◽  
Speed Up ◽  
On Line ◽  
Start Ups ◽  
State Restrictions

The article investigates history of establishment and development of start-up unicorn-companies with capitalization over $ 1bn. The authors analyzed key types of unicorn-companies (unicorns, decacorns quinquagintacorns, gectacorns), identified their principle characteristics, showed criteria and factors of their success. The role of venture funds was studied, as they are major investors into promising business-projects. The article described trends of the 1-st half of 2020, the time of state restrictions and pandemic, such as distant work, IT entertainments, could services, on-line delivery, marketplaces, drop in business activity, which require clients' presence. It also showed the process of business-projects' passing from start-ups to companies with high capitalization. The authors pointed out that to create a successful company with capitalization of $ 1bn you do not need any special conditions, but there is certain logic concerning how the start-up can become unicorn-company. Basic points of this logic were provided. The authors substantiated the necessity of venture fund promotion among entrepreneurs and investors in order to speed up the start of start-ups and development of business-projects to the level of big companies.

scholarly journals Multiyear patterns regarding the relative availability of venture capital for the US biotechnology industry

1969 ◽  
Vol 15 (4) ◽  
Author(s):  
J Leslie Glick
Keyword(s):  
Venture Capital ◽  
Early Stage ◽  
Coming Of Age ◽  
Personalised Medicine ◽  
Biotechnology Industry ◽  
Long Run ◽  
Start Up ◽  
The Us ◽  
Biotechnology Companies ◽  
Long Term Trends

Venture capital (VC) funding of US biotechnology companies was analysed relative to total VC investments placed in US companies from 1995 to 2007. During those years, except for a spike because of the dot-com bubble from 1999 to 2001, VC funding of US biotechnology companies grew at a faster rate percentagewise than total VC funding of US companies, with respect to annual dollars invested, number of deals closed and the mean dollar investment. Start-up and early-stage VC funding of US biotechnology companies also grew at a faster rate percentagewise, with respect to all three parameters, than total start-up and early-stage VC funding of US companies. It was further observed that long-term trends in the availability of VC for biotechnology do not appear to be affected by perturbations in the financial markets and short-term fluctuations in the availability of VC. It was concluded that the biotechnology industry should continue to attract VC over the long run particularly because of the emerging impact of personalised medicine and the coming of age of bioenergy.

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