scholarly journals Bacterial quality control of domestic and imported brands of bottled water in Saudi Arabia

2013 ◽  
Vol 5 (10) ◽  
pp. 178-184
Author(s):  
Al Hazzani
Keyword(s):  
Quality Control ◽  
Saudi Arabia ◽  
Bottled Water

scholarly journals Diversity of fungi in bottled water in Jeddah, Saudi Arabia

2017 ◽  
Vol 18 (5) ◽  
pp. 1664-1673 ◽  
Author(s):  
Fuad Ameen ◽  
Alhanouf Albejad ◽  
Rukaia Gashgari ◽  
S. Murialdo ◽  
A. Al-Sabri
Keyword(s):  
Drinking Water ◽  
Saudi Arabia ◽  
Water Samples ◽  
Water System ◽  
Fungal Species ◽  
Bottled Water ◽  
Fungal Contamination ◽  
Jeddah City ◽  
Drinking Water System ◽  
Molecular Sequencing

Abstract The occurrence of fungi in drinking water systems has received increased attention over recent decades and fungi are now generally accepted as drinking water system contaminants. However, fungal contamination of bottled water has received little attention. Forty unopened bottled water samples, of different trademarks, were collected from various localities in Jeddah city, Saudi Arabia and analyzed for fungal contamination: (1) immediately after opening the bottles; and (2) after closing and storing them for 180 and 365 days. The fungal species were identified under a compound microscope followed by molecular sequencing. At least one fungal species were found in 58% of the bottles. In total, 18 fungal species belonging to 11 fungal genera were identified. Rhizopus nigricans and seven different species of Aspergillus were found to frequently contaminate the bottled water samples. Penicillium sp. were found in one sample. The 180 days storage of opened and reclosed bottles did not substantially affect the abundance of fungi or the species found. Some of the fungi identified may be pathogenic and the contamination of fungi in bottled water should be considered during the processing of water.

Quality control practices in Saudi Arabia: Survey result

1997 ◽  
Vol 8 (8) ◽  
pp. 726-730 ◽  
Author(s):  
U. Al-turki ◽  
A. Andijani
Keyword(s):  
Quality Control ◽  
Saudi Arabia ◽  
Survey Result

scholarly journals Quality Control Measurement and in vitro Bioequivalence of Candesartan Cilexetil Tablets Marketed in Saudi Arabia

2020 ◽  
pp. 155-163
Author(s):  
Mohammed Al- Bratty ◽  
Hassan A. Alhazmi ◽  
Hafiz A. Makeen ◽  
Asim Najmi ◽  
Md Shamsher Alam ◽  
...  
Keyword(s):  
Quality Control ◽  
Saudi Arabia ◽  
Comparative Analysis ◽  
Ir Spectra ◽  
Active Ingredient ◽  
Candesartan Cilexetil ◽  
Hypertensive Patients ◽  
Ft Ir ◽  
Pure Drug

Aim: Some generics were reported to be counterfeit and inferior quality than the innovators. This study was aimed to make sure about the compliance with standard specifications and evaluation of the quality of different selected brands (generic and innovator), after performing different pharmacopeial quality control tests, of Candesartan cilexetil tablets (16 mg) commercially available in Saudi Arabia for hypertensive patients. Study Design: In vitro study of tablets. Place and Duration of Study: College of Pharmacy, Jazan University, Jazan, KSA, between September 2018 and May 2019.            Methodology: The different generic brands of Candesartan cilexetil (CC) and innovator brand (16 mg) were subjected to weight variation, hardness, friability, assay, and disintegration tests following the established protocols. The purity of active ingredient was authenticated by comparative analysis of FT-IR spectra with pure drug. In vitro bioequivalence was studied after analyzing the results of dissolution summaries in phosphate buffer (pH 6.5) mixed with polysorbate 20 (0.35% v/v). Results: The results of the tests conducted for evaluation of the tablets were found to be in acceptable limits for all the selected brands. After comparative analysis of FT-IR spectra with pure drug, it was inferred that correct active ingredient was used for the preparation of tablets. The drug release profile exhibited 96.89 – 101.97% of release of CC from all generic brands, in comparison to 99.4% for innovator brand after 60 min of study. The assessment of difference factor (f1<15) and similarity factor (f2>50) revealed the resemblance of generic brands with that of innovator brand. Furthermore, the dissolution efficiency (DE = ±10% of the innovator value) of all generic brands (73.12 – 73.25%) exhibited equivalency with that of innovator brand (70.45%). Conclusion: The selected generics were considered to be biopharmaceutically equivalent to the innovator and maintained their efficacy. As a consequence, these brands can be used interchangeably by the hypertensive patients in Saudi Arabia.

scholarly journals Analisis Ketidaksesuaian Produk Air Minum dalam Kemasan di PT Amanah Insanillahia

2016 ◽  
Vol 14 (1) ◽  
pp. 99 ◽  
Author(s):  
Elita Amrina ◽  
Nofriani Fajrah
Keyword(s):  
Quality Control ◽  
Central Line ◽  
Bottled Water ◽  
Water Industry ◽  
Fishbone Diagram ◽  
Preliminary Study ◽  
Quality Of Products ◽  
A Company ◽  
Control Limits

Nowadays, the development of industry is increasing very rapidly. It can be known as the high competition between companies. Not only large and international scaled companies, small and medium-sized companies are also face the same challenges in the global competition. Therefore, the companies need to conduct a quality control to maintain the quality of products produced and to achiece the conformance to specifications of product that has standardized by the company policies in order to improve the customer satisfaction. PT Amanah Insanillahia is a company involved in the bottled water industry. Based on the preliminary study, it shown the quality control only conducted to check the number of defective products produced without further evaluation and analysis. Therefore, there is a need to analyze the data of defective products produced and evaluate the results. The purpose of this study is to analyze the nonconformity product of the bottled water 600 ml brand PRIM-A. The p-chart is used in this research to analyze the number of defective products. Then, the fishbone diagram is used to analyze the causes of defective products. The results show that there is no data out of the control limits and mostly the data near in the central line of the p-chart. Using the fishbone diagram, it concluded that factors of man, machines, materials, methods, and environment are the causes of nonconformity products of the bottled water 600 ml brand PRIM-A. It is hoped this study will beneficial for the company to improve the product quality as well as to increase the customer satisfaction.Key Words:Bottled water, nonconformity, p-chart, quality, fishbone diagram AbstrakDewasa ini perkembangan dunia industri bergerak sangat pesat. Hal ini dapat diketahui berdasarkan persaingan antar perusahaan yang semakin meningkat dan lebih ketat. Tidak hanya perusahaan berskala besar dan internasional, namun perusahaan kecil dan menengah juga mengalami persaingan global. Oleh karena itu perusahaan perlu melakukan pengendalian kualitas untuk mempertahankan kualitas dari produk yang dihasilkan, agar sesuai dengan spesifikasi produk yang telah ditetapkan berdasarkan kebijakan perusahaan sehingga akan menciptakan kepuasan konsumen. PT Amanah Insanillahia merupakan perusahaan yang bergerak di industri Air Minum Dalam Kemasan (AMDK). Berdasarkan studi pendahuluan yang dilakukan diketahui bahwa pengendalian kualitas hanya dilakukan dalam batas pengecekan jumlah produk cacat yang dihasilkan tanpa dievaluasi maupun dianalisis lebih lanjut. Oleh karena itu perlu untuk menganalisis data produk cacat yang dihasilkan dan mengevaluasi hasilnya. Tujuan penelitian ini adalah untuk menganalisis ketidaksesuaian produk air minum kemasan botol 600 ml merek PRIM-A. Peta p digunakan dalam penelitian ini untuk menganalisis jumlah produk yang cacat. Kemudian diagram fishbone digunakan untuk menganalisis penyebab ketidaksesuaian produk. Hasil penelitian menunjukkan tidak terdapat data yang keluar batas kontrol dan sebagian besar produk berada didekat garis tengah dari Peta kendali p. Dari diagram fishbone didapatkan bahwa faktor manusia, mesin, bahan baku, metode, dan lingkungan merupakan penyebab ketidaksesuaian produk air minum kemasan botol 600 ml merek PRIM-A. Penelitian ini diharapkan dapat bermanfaat bagi perusahaan untuk meningkatkan kualitas produk dan kepuasan konsumen.Kata Kunci: Air minum dalam kemasan, ketidaksesuian, peta p, kualitas, diagramfishbone

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