Effects of the alcoholic root extract of the male Carica papaya on ovulation, gestation and fetal parameters in female Sprague- Dawley rats

2012 ◽  
Vol 6 (16) ◽  
Author(s):  
Adigwe C. C
Keyword(s):  
Carica Papaya ◽  
Root Extract ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals A comparative study of efficacy of argyreia speciosa and orlistat for their anti-obesity action in high fat diet induced obese rats

2017 ◽  
Vol 6 (3) ◽  
pp. 613 ◽  
Author(s):  
Suhas H. Patil ◽  
Satkar Rajbhoj ◽  
Seema V. Bhalerao ◽  
Puja Jha ◽  
Manasi V. Limaye ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
Atherogenic Index ◽  
Root Extract ◽  
Sprague Dawley ◽  
Serum Lipase ◽  
Sprague Dawley Rats ◽  
Animal House ◽  
Post Hoc

Background: To compare the anti-obesity action of Argyreia speciosa root extract with standard anti-obesity drug orlistat. Healthy Sprague-Dawley rats (100-200g, n=50) were obtained from the animal house. Dose of Orlistat was 32.4mg/kg/day and Dose of Argyreia speciosa root was 500mg/kg/day.Methods: Food induced obesity model was used. Following parameters were evaluated: Total Cholesterol (mg/dl), Triglyceride (mg/dl), HDL-cholesterol (mg/dl), LDL cholesterol (mg/dl), atherogenic index, serum lipase (U/L). Analysis was done by one way ANOVA followed by post-hoc test and Graph Pad Prism version 5.00 was used for the analysis.Results: Total cholesterol, triglcerides, LDL cholesterol and Atherogenic index was significantly lesser in the rats fed with CD+O group and CD+ASE group than in the animals from CD group (p<0.05). It was also significantly lesser in the rats fed with CD+O+ASE than in the animals from CD group (p<0.05). HDL cholesterol was significantly greater in the rats fed with CD+O group and CD+ASE group than in the animals from CD group (p<0.05). It was also significantly greater in the rats fed with CD+O+ASE than in the animals from CD group (p<0.05).Conclusions: ASE significantly reduces total cholesterol (mg/dl), triglyceride (mg/dl), LDL cholesterol (mg/dl) and atherogenic index, it significantly increases HDL- cholesterol (mg/dl) and it is comparable to orlistat. Thus the anti-obesity action of ASE is comparable to orlistat.

scholarly journals Repeated Dose 28-Days Oral Toxicity Study of Carica papaya L. Leaf Extract in Sprague Dawley Rats

Molecules ◽  
2012 ◽  
Vol 17 (4) ◽  
pp. 4326-4342 ◽  
Author(s):  
Adlin Afzan ◽  
Noor Rain Abdullah ◽  
Siti Zaleha Halim ◽  
Badrul Amini Rashid ◽  
Raja Hazlini Raja Semail ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Carica Papaya ◽  
Toxicity Study ◽  
Repeated Dose ◽  
Sprague Dawley ◽  
Oral Toxicity ◽  
Sprague Dawley Rats

scholarly journals Anti-Oxidative Potential of Acalypha indica L. Root Extract on Brain-Derived Neurotrophic Factor Levels in Old Sprague-Dawley Rats

2018 ◽  
Author(s):  
Callen Zulkifli ◽  
Reganedgary Jonlean ◽  
Adisti Dwijayanti ◽  
Desak Gede Budi Krisnamurti ◽  
Erni Hernawati Purwaningsih ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Root Extract ◽  
Sprague Dawley ◽  
Oxidative Potential ◽  
Sprague Dawley Rats ◽  
Acalypha Indica
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