Effects of the novel herbal medicine, KIOM-C, on the growth performance and immune status of porcine circovirus associated disease (PCVAD) affected pigs

2012 ◽  
Vol 6 (28) ◽  
Author(s):  
Tae Ho Chung,
Keyword(s):  
Herbal Medicine ◽  
Growth Performance ◽  
Immune Status ◽  
Porcine Circovirus ◽  
The Novel

scholarly journals Effect of feeding different dietary levels of energy and protein on growth performance and immune status of Vanaraja chicken in the tropic

2016 ◽  
Vol 9 (8) ◽  
pp. 893-899 ◽  
Author(s):  
Shahla Perween ◽  
Kaushalendra Kumar ◽  
Chandramoni ◽  
Sanjay Kumar ◽  
Pankaj Kumar Singh ◽  
...  
Keyword(s):  
Growth Performance ◽  
Immune Status ◽  
Effect Of Feeding

scholarly journals The Effect of Dietary Replacement of Fish Meal with Whey Protein Concentrate on the Growth Performance, Fish Health, and Immune Status of Nile Tilapia Fingerlings, Oreochromis niloticus

Animals ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 1003 ◽  
Author(s):  
Shimaa A. Amer ◽  
Ali Osman ◽  
Naif A. Al-Gabri ◽  
Shafika A. M. Elsayed ◽  
Ghada I. Abd El-Rahman ◽  
...  
Keyword(s):  
Growth Performance ◽  
Oreochromis Niloticus ◽  
Caspase 3 ◽  
Fish Meal ◽  
Immune Status ◽  
Histopathological Examination ◽  
Whey Protein Concentrate ◽  
Bacterial Challenge ◽  
Cellular Apoptosis ◽  
Fish Meal Replacement

The present study was conducted to assess the effect of replacing fish meal with whey protein concentrate (WPC) on the growth performance, histopathological condition of organs, economic efficiency, disease resistance to intraperitoneal inoculation of Aeromonas hydrophila, and the immune response of Oreochromis niloticus. The toxicity of WPC was tested by measuring the activity of caspase 3 as an indicator of cellular apoptosis. Oreochromis niloticus fingerlings with average initial weight 18.65 ± 0.05 gm/fish (n = 225) for a 10-week feeding trial. The fish were randomly allocated to five experimental groups, having five replacement percentages of fish meal with WPC: 0%, 13.8%, 27.7%, 41.6%, and 55.5% (WPC0, WPC13.8, WPC27.7, WPC41.6, and WPC55.5); zero percentage represented the control group. The results show that the fish fed WPC had the same growth performance as the WPC0. The total weight of bacterially challenged surviving fish increased linearly and quadratically (p ≤ 0.05) by increasing the replacement percentage of fish meal with WPC. The growth hormone, nitric oxide, IgM, complement 3, and lysozyme activity were seen to increase significantly in WPC27.7, especially after a bacterial challenge. The phagocytic percentage and phagocytic index increased significantly in WPC27.7, WPC41.6, and WPC55.5 groups. Histopathological examination of liver sections was badly affected by high replacement in WPC41.6–55.5. The activity of caspase 3 in the immunohistochemical stained sections of the intestine was increased significantly by increasing the inclusion level of WPC. Economically, the total return of the total surviving fish after the bacterial challenge was increased significantly by fish meal replacement with WPC. It could be concluded that WPC could replace the fish meal in Nile tilapia diets up to 27.7%, with improving the gut health, the total weight of survival fish, and immune status of fish challenged with A. hydrophila. High inclusion levels of WPC are not recommended in fish diets, since they negatively affected the intestinal and liver tissues and increased the level of cellular apoptosis, as indicated by the increased caspase 3 activity. Further researches are recommended to evaluate the effect of fish meal replacement with WPC on the histopathological examination of the kidney and to test the capacity of serum IgM to clot the bacteria used for the challenge.

scholarly journals Effects of Dietary Supplementation of Humic Acid Sodium and Zinc Oxide on Growth Performance, Immune Status and Antioxidant Capacity of Weaned Piglets

Animals ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2104
Author(s):  
Qi Wang ◽  
Jiafu Ying ◽  
Peng Zou ◽  
Yuanhao Zhou ◽  
Baikui Wang ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Body Weight ◽  
Antioxidant Capacity ◽  
Growth Performance ◽  
Immune Status ◽  
Immunoglobulin M ◽  
Control Group ◽  
High Dose ◽  
Weaned Piglets ◽  
Basic Diet

At present, the widespread use of high-dose zinc oxide and antibiotics to prevent post-weaning diarrhea (PWD) in piglets has caused serious environmental problems. To solve this problem, we studied the effect of HNa as a substitute for zinc oxide (ZnO) and antibiotics on the growth performance, immune status, and antioxidant capacity of piglets. Seventy-two weaned piglets (body weight = 7.42 ± 0.85 kg, 26-d-old) were distributed in a randomized 2 × 3 factorial design (two sexes and three treatments) with six replicates of four piglets each. The three treatments were the control diet (basic diet), HNa diet (basic diet + 2000 mg/kg sodium humate), and ZoA group (basic diet + 1600 mg/kg zinc oxide + 1000 mg/kg oxytetracycline calcium). ANOVA and Chi-square tests were applied to compare the means (p < 0.05) between treatments. The results showed that body weight at 16 and 30 d and the average daily gain of piglets fed with HNa or ZoA were significantly higher (p < 0.05) than the control group. Supplementing HNa or ZoA significantly increased (p < 0.05) the level of immunoglobulin M and G, and reduced (p < 0.05) the concentration of inflammatory factors such as tumor necrosis factor-alpha (TNF-α), interleukins IL-6 and IL-1β, myeloperoxidase (MPO), and diamine oxidase (DAO). Furthermore, dietary HNa or ZnO significantly reduced (p < 0.05) the level of total antioxidant capacity (T-AOC) and malondialdehyde (MDA) compared with the control group. ZoA treatment showed an upward trend of IgA level and a downward trend of the concentration of lipopolysaccharide (LPS) and catalase (CAT). Overall, the study demonstrated that the addition of HNa in the diet partially replaced antibiotics and ZnO to improve the growth performance, immune function, and antioxidant capacity of weaned piglets, and maintained a good preventive effect on piglet diarrhea.

scholarly journals Effects of dietary seaweed extract supplementation in sows and post-weaned pigs on performance, intestinal morphology, intestinal microflora and immune status

2011 ◽  
Vol 106 (5) ◽  
pp. 688-699 ◽  
Author(s):  
S. G. Leonard ◽  
T. Sweeney ◽  
B. Bahar ◽  
B. P. Lynch ◽  
J. V. O'Doherty
Keyword(s):  
Growth Performance ◽  
Intestinal Microflora ◽  
Immune Status ◽  
Average Daily Gain ◽  
Intestinal Morphology ◽  
Seaweed Extract ◽  
Gut Health ◽  
Weaned Pigs ◽  
Treatment Groups ◽  
Daily Gain

The present study investigated the effects of dietary supplementation of a seaweed extract (SWE) to sows and weaned pigs on post-weaning growth performance, intestinal morphology, intestinal microflora, volatile fatty acid concentrations and immune status of pigs at days 11 and 117 post-weaning. Gestating sows (n20) were supplemented with a SWE (0v.10·0 g/d) from day 107 of gestation until weaning (day 26). At weaning, pigs (four pigs per sow) were divided into two groups based on sow diet during lactation and supplemented with a SWE (0v.2·8 g/kg diet), resulting in four treatment groups: (1) BB (basal sows–basal pigs); (2) BS (basal sows–treated pigs); (3) SB (treated sows–basal pigs); (4) SS (treated sows–treated pigs). Pigs weaned from SWE-supplemented sows had a higher average daily gain (ADG) between days 0 and 21 (P < 0·05) post-weaning compared with pigs weaned from non-SWE-supplemented sows. Pigs offered post-weaning diets (PW) containing SWE had decreased colonicEscherichia colipopulations on day 11 (P < 0·01) and decreased colonic Enterobacteriaceae numbers on day 117 (P < 0·05). Pigs offered PW containing SWE had a greater mRNA abundance ofMUC2in the colon at day 11 post-weaning (P < 0·05) compared with pigs offered unsupplemented diets. In conclusion, these results demonstrate that SWE supplementation post-weaning provides a dietary means to improve gut health and to enhance growth performance in starter pigs. Dietary SWE supplementation increased ADG during the grower–finisher (GF) phases. However, there was no growth response to SWE inclusion in GF diets when pigs were weaned from SWE-supplemented sows.

309 Evaluation of a QTL for porcine circovirus type 2b (PCV2) viral load on growth performance in inoculated and vaccinated pigs for PCV2

2016 ◽  
Vol 94 (suppl_2) ◽  
pp. 145-145
Author(s):  
D. M. van Sambeek ◽  
E. R. Tosky ◽  
P. S. Miller ◽  
D. C. Ciobanu ◽  
T. E. Burkey
Keyword(s):  
Viral Load ◽  
Growth Performance ◽  
Porcine Circovirus Type ◽  
Porcine Circovirus

Do different vaccination regimes affect the growth performance, immune status, carcase characteristics and meat quality of broilers?

2020 ◽  
pp. 1-6
Author(s):  
E. L. T. Chung ◽  
M. M. Alghirani ◽  
M. H. Kamalludin ◽  
N. Nayan ◽  
F. F. A. Jesse ◽  
...  
Keyword(s):  
Growth Performance ◽  
Meat Quality ◽  
Immune Status

scholarly journals In VivoEfficacy of a Human-Simulated Regimen of Ceftaroline Combined with NXL104 against Extended-Spectrum-β-Lactamase (ESBL)-Producing and Non-ESBL-Producing Enterobacteriaceae

2011 ◽  
Vol 55 (7) ◽  
pp. 3220-3225 ◽  
Author(s):  
Dora E. Wiskirchen ◽  
Jared L. Crandon ◽  
Guilherme H. Furtado ◽  
Gregory Williams ◽  
David P. Nicolau
Keyword(s):  
Immune Status ◽  
Free Drug ◽  
Infection Model ◽  
The Novel ◽  
Immunocompetent Host ◽  
Content Type ◽  
Extended Spectrum ◽  
Drug Concentrations ◽  
Immunocompetent Mice

ABSTRACTCeftaroline exhibitsin vitroactivity against extended-spectrum β-lactamase (ESBL)-, AmpC-, and KPC-producingEnterobacteriaceaewhen combined with the novel β-lactamase inhibitor NXL104. The purpose of this study was to evaluate the efficacy of a human-simulated regimen of ceftaroline plus NXL104 againstEnterobacteriaceaein a murine thigh infection model.IMPORTANCETwelveEnterobacteriaceaeisolates were tested with neutropenic ICR mice. Seven of these isolates were also tested with immunocompetent mice. Doses were given to simulate human free-drug exposures of ceftaroline (600 mg) plus NXL104 (600 mg) every 8 h over 24 h by targeting the percentage of time that free drug concentrations remain above the MIC, ƒT>MIC. The change in log10CFU/ml compared with 0 h controls was observed after 24 h. Human-simulated exposures were achieved against all isolates (MICs of ≤0.015 to 1 μg/ml) in both the neutropenic and the immunocompetent host models, which was equivalent to a ƒT>MIC of 100%. A 0.5 to ≥2 log CFU reduction was observed in the neutropenic thigh infection model. Furthermore, significantly greater reductions in bacterial density were observed for five of seven isolates studied in an immunocompetent model than in the neutropenic-host model. Regardless of immune status, ceftaroline (600 mg) combined with NXL104 (600 mg) every 8 h provided predictable efficacy against ESBL-, non-ESBL-, and KPC-producing isolates with an MIC of ≤1 μg/ml and could be useful in combating the growing threat of resistantEnterobacteriaceae.

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