Two step growth process of iron-platinum (FePt) nanoparticles

Author(s):  
Majid Farahmandjou
2004 ◽  
Vol 267 (1-2) ◽  
pp. 17-21 ◽  
Author(s):  
M.C. Debnath ◽  
T. Zhang ◽  
C. Roberts ◽  
L.F. Cohen ◽  
R.A. Stradling

1992 ◽  
Vol 242 ◽  
Author(s):  
T. D. Moustakas ◽  
R. J. Molnar ◽  
T. Lei ◽  
G. Menon ◽  
C. R. Eddy

ABSTRACTGaN films were grown on c-plane (0001), a-plane (1120) and r-plane (1102) sapphire substrates by the ECR-assisted MBE method. The films were grown using a two-step growth process, in which a GaN buffer is grown first at relatively low temperatures and the rest of the film is grown at higher temperatures. RHEED studies indicate that this growth method promotes lateral growth and leads to films with smooth surface morphology. The epitaxial relationship to the substrate, the crystalline quality and the surface morphology were investigated by RHEED, X-ray diffraction and SEM studies.


2007 ◽  
Vol 17 (1) ◽  
pp. 52-55 ◽  
Author(s):  
Sudhanshu Srivastava ◽  
Bappaditya Samanta ◽  
Palaniappan Arumugam ◽  
Gang Han ◽  
Vincent M. Rotello

2006 ◽  
Vol 203 (1) ◽  
pp. 162-166 ◽  
Author(s):  
A. Delimitis ◽  
P. Gladkov ◽  
Ph. Komninou ◽  
Th. Kehagias ◽  
J. Arvanitidis ◽  
...  
Keyword(s):  

2016 ◽  
Author(s):  
◽  
Emilia Ohsone-Zargham Mason

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Cancer is the second leading cause of death in the United States, exceeded only by heart disease, and it is estimated that one in every four deaths is due to cancer.1 Many therapeutic techniques that are currently used are often severely limited and can cause adverse effects, which prevents the aggressive treatment of late stage cancers. Significant improvements are needed involving early detection and more selective treatment options. Much interest has been shown in the development of materials that are highly selective and capable of being used in both therapeutic and diagnostic applications.2,3 nanoparticles have been shown to passively accumulate in tumors, making them useful materials for developments in cancer research.4 Iron-platinum (FePt) nanoparticles have an excellent potential as delivery agents for medicinal applications. Superparamagnetic FePt nanoparticles were embedded in a surface-functionalized polymeric shell as drug delivery platforms. The FePt core offers improved characteristics for magnetic resonance imaging (MRI) over currently used materials. The FePt nanoparticles were optimized to sizes between 2 to 6 nanometers and their physical and magnetic properties were also analyzed. The amount of surfactants used during the synthesis had a significant effect on the size and shape of the nanoparticles. The altered synthetic parameters resulted in the formation of both cubic and spherical nanoparticles. Face-centered cubic (fcc) unit cell structures were produced, which could also be thermally annealed to form the more ordered face-centered tetragonal (fct) structures. The fcc and fct unit cell structures of the FePt nanoparticles were characterized using powder X-ray diffraction (XRD). The FePt nanoparticle cores were coated using an emulsion polymerization reaction to increase their stability in biological systems.5 The polystyrene coating was optimized to produce an overall size of approximately 12 to 30 nanometers. The magnetic characteristics of the coated FePt nanoparticles were analyzed by MRI. Dynamic light scattering (DLS), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDS), and inductively coupled plasma mass spectrometry (ICP-MS) were also used to characterize the size and composition of the nanoparticles. The coated nanoparticles were functionalized with azides on the surface and analyzed using both Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR). beta-cyclodextrin was attached to the surface of the nanoparticles using a click chemistry reaction. The hydrophobic cavity of the beta-cyclodextrin allows for the incorporation of hydrophobic drugs for subsequent delivery. These superparamagnetic FePt coated and functionalized nanoparticles show great potential to selectively treat and diagnosis various types of cancer and diseases.6 Furthermore, there are numerous drugs such as FK866, doxorubicin, gemcitabine, and paclitaxel that are used to treat various types of cancer. Many of these drugs have different mechanisms by which they cause cell death. New derivatives of FK866, considered to be one of the most potent anti-cancer drugs, have been developed through the inclusion of carboranes.7,8 These drugs have shown increased potency and antiproliferative activity against cancer cells in vitro through the use of various cell culture assays.9/11 The inhibitory concentrations on various cells lines were reported through the use of MTT colorimetric assays.12 Drug combinations were also performed and analyzed using CompuSyn to determine the existence of any synergistic effects.


2009 ◽  
Vol 129 (9) ◽  
pp. 1036-1041 ◽  
Author(s):  
Nobuaki Kitazawa ◽  
Dhebbajaji Yaemponga ◽  
Masami Aono ◽  
Yoshihisa Watanabe

1988 ◽  
Vol 116 ◽  
Author(s):  
S.M. Prokes ◽  
W.F. Tseng ◽  
B.R. Wilkins ◽  
H. Dietrich ◽  
A. Christou

AbstractEpitaxial SiGe buffers have been formed by the implantation of 74Ge+ ions into Si(100)4° to <011> substrates. The implants were made at 150keV to a dose of 1×1017 /cm2 . The epitaxial layers were characterized by Rutherford backscattering, Raman spectroscopy, and electroreflectance and were found to be 300Å thick having on average a composition of Si0 . 35 Ge0.65. GaAs layers were then grown on these substrates by molecular beam epitaxy, using the standard two-step growth process. The results from Auger, Scanning Electron Microscopy, and Cross-sectional TEM indicate a lower defect production and propagation in these samples, compared to those grown directly on Si.


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