scholarly journals Polymorphisms of two neuroendocrinecorrelated genes associated with body weight and reproductive traits in Jinghai yellow chicken

2011 ◽  
Vol 10 (54) ◽  
pp. 11124-11129 ◽  
Author(s):  
Hua Zhao Xiu ◽  
Yu Wang Jin ◽  
Xi Zhang Gen ◽  
Wei Yue ◽  
Bo Yu Ya
2016 ◽  
Vol 24 (3) ◽  
pp. 213 ◽  
Author(s):  
E.M. Abdel-Kafy ◽  
S.F. Darwish ◽  
D. ElKhishin

The Myostatin (MSTN), or Growth and Differentiation Factor 8 (GDF8), gene has been implicated in the double muscling phenomenon, in which a series of mutations render the gene inactive and unable to properly regulate muscle fibre deposition. Single nucleotide polymorphisms (SNPs) in the MSTN gene have been correlated to production traits, making it a candidate target gene to enhance livestock and fowl productivity. This study aimed to assess any association of three SNPs in the rabbit MSTN gene (c.713T>A in exon 2, c.747+34C>T in intron 2, and c.*194A>G in 3’-untranslated region) and their combinations, with carcass, production and reproductive traits. The investigated traits included individual body weight, daily body weight gain, carcass traits and reproductive traits. The 3 SNPs were screened using PCR-restriction fragment length polymorphism (RFLP)-based analysis and the effects of the different SNP genotypes and their combinations were estimated in a rabbit population. Additionally, additive and dominance effects were estimated for significant traits. The results found no significant association between the c.713 T>A SNP and all the examined traits. Allele T at the c.747+34C>T SNP was only significantly associated (P<0.05) with increased body weight at 12 wk of age. However, for the SNP residing in the 3’ untranslated region (c.*194A>G), allele G was significantly associated (P<0.05) with increased body weight and high growth rate. Genotype GG at the c.*194A>G SNP also had positive effects on most carcass traits. The estimated additive genetic effect for the c.*194A>G SNP was significant (P<0.05) with most body weight, daily gain and carcass traits. No significant association was obtained between any MSTN SNPs and reproductive traits. In the combinations analysis, regardless of the genotypes of SNPs at c.713T>A and c.747+34C>T, GG at the c.*194A>G SNP correlated with highest values in body weight and daily weight gain. In conclusion, the ‘G’ allele at the c.*194A>G SNP had positive effects on growth and carcass traits and so could be used as a favourable allele in planning rabbit selection. Further population-wide studies are necessary to test the association of the c.*194A>G SNP with carcass traits. We also recommend evaluation of the potential effects of the c.*194A>G SNP on MSTN gene expression.


2020 ◽  
Vol 9 (1) ◽  
pp. e111911723
Author(s):  
Gabriela Queiroz Faria ◽  
Héder José D'Ávila Lima ◽  
Leonardo da Silva Costa ◽  
Jéssica Amaral Miranda ◽  
Graziela Maria Freitas Rocha ◽  
...  

The objective of this study was to determine the effect of dietary calcium levels on productive and reproductive traits of European male quail (Coturnix coturnix). A total of 60 European male quail, at 35 days of age, weighing 248.9g ± 8.1g were distributed in a completely randomized experimental design with five calcium levels (1.5, 2.0, 2.5, 3.0 and 3.5%), and 12 replicates per treatment (one bird each replicate). The experimental period was 35 to 70 days of age. At 70 days of age, the parameters of male productive traits assessed were: feed consumption, calcium consumption, weight gain and body weight of birds. The reproductive traits analyzed were: hatchability and fertility of eggs. Early, intermediate and late embryonic mortality were also evaluated. The diet containing 3.16% of calcium provides higher percentage of hatched eggs and did not show a negative effect on productive performance of European quails.


2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Lingbin Liu ◽  
Zhifu Cui ◽  
Qihai Xiao ◽  
Haihan Zhang ◽  
Xiaoling Zhao ◽  
...  

The aim of the study was to investigateGDF9gene polymorphisms and their association with reproductive traits in chicken using DNA sequencing. A total of 279 Dongxiang blue-shelled (DX) chickens and 232 Luhua (LH) chickens were used for validation. We detected 15 single nucleotide polymorphisms (SNPs): nine SNPs were previously unreported in chicken, two were missense mutations, and only three exhibited significant associations with reproductive traits. G.17156387C>T was significantly associated with age at first egg (AFE) and weight of first egg (WFE) in both breeds. Birds carrying the CC genotype exhibited higher AFE and WFE values than those with the TT genotype. The SNP g.17156427A>G exhibited an association with egg weight at 300 days of age (EWTA) in DX but not in LH chickens. The SNP g.17156703A>C affected the AFE and EN (total number of eggs at 300 days of age) in DX chickens. In addition, certain diplotypes significantly affected AFE, BWTA (body weight at 300 days of age), and EN in both breeds. RT-PCR results showed that theGDF9gene was highly expressed in stroma with cortical follicles (STR) and prehierarchal follicles. These results provided further evidence that theGDF9gene is involved in determining reproductive traits in chicken.


Author(s):  
M. Sarma ◽  
R. Islam ◽  
M. K. Borah ◽  
P. Sharma ◽  
J. D. Mahanta ◽  
...  

A study was conducted covering a total of one hundred chicken farmers in tribal dominated Boko Block of Kamrup district in Assam to assess different productive and reproductive traits of Desi, Vanaraja and Srinidhi birds under field condition. Information was obtained on mean body weight at various ages, age at first egg, annual egg production, fertility and hatchability and mortality rate. Body weight, egg production and egg weight were significantly (P£0.05) higher in Vanaraja and Srinidhi birds compared to Desi chicken. The age at first egg was significantly (P£0.05) higher in Desi chicken while compared with Vanaraja and Srinidhi under traditional system of management. However no significant (P£0.05) difference was found between Vanaraja and Srinidhi in their body weight and egg production at various ages. Higher mortality percent in Vanaraja (12.23±1.62) and Srinidhi (11.34±1.23) were recorded during 0 to 5 week. No significant (P£0.05) differences were found among all three groups of birds in fertility and hatchability.


2000 ◽  
Vol 75 (2) ◽  
pp. 199-208 ◽  
Author(s):  
K. R. PARKS ◽  
E. J. EISEN ◽  
I. J. PARKER ◽  
L. G. HESTER ◽  
J. D. MURRAY

Correlated responses in female reproductive performance were evaluated following short-term selection within full-sib families for increased 8-week body weight in two replicates of four lines of mice: two ovine metallothionein–ovine growth hormone (oMt1a-oGH) transgene-carrier lines, one from a high-growth background (TM) and one from a control background (TC), and two non-transgenic lines, one from each of these genetic backgrounds (NM and NC, respectively). A fifth line (CC), not containing the transgene, served as a randomly selected control. The initial frequency of the oMt1a-oGH transgene construct in the TM and TC lines was 0·5. The frequency of transgenic females sampled at generations 7 and 8 of selection was 84·0% and 6·1% in the TC and TM lines, respectively. No significant female infertility differences were detected between transgene-carrier and non-transgenic lines or between transgenic and non-transgenic mice within carrier lines, whereas high-growth background lines had a higher infertility than control background lines (P < 0·05). Correlated responses in the TC transgene-carrier line were suggestive of reduced reproductive performance as indicated by increased post-implantation mortality (P < 0·05), number of dead fetuses plus implants (P < 0·05), and loss of fetuses from day 16 to parturition (P < 0·001). For the first two traits, the negative correlated responses were accounted for by the reduced performance of transgenic compared with non-transgenic females. Embryos carrying the transgene may also have a lower viability. In contrast, the NC non-transgenic line did not exhibit reduced reproductive performance for these traits. The low frequency of the transgene in the high-growth background TM line was associated with reduced fitness and a lower additive effect for 8-week body weight compared with the control background TC line.


2020 ◽  
Author(s):  
Margaretha Snyman ◽  
Sunika Süllwald ◽  
Willem Olivier ◽  
Carina Visser

Abstract Background: Reproductive performance and body weight are of the utmost economic importance in determining the efficiency of sheep production. Simultaneous selection for increased reproductive performance and early growth traits is a common strategy in many flocks, but ambiguous results regarding the relationship between reproduction and body weight have been reported. The objective of this study was to perform a genome-wide association study (GWAS) in two South African Merino flocks and an Afrino sheep flock that were selected for both reproduction and body weight over decades. The GWAS aimed to identify SNPs associated with genes affecting the traits number of lambs born (NLB), number of lambs weaned (NLW), total weight of lamb weaned (TWW) and body weight (BW) and thus to ascertain which genes were targeted through directional selection.Results: In the GWAS, 16 SNP markers associated with reproductive traits were identified among the three populations, while 15 SNPs were associated with body weight. These SNPs were linked respectively to 26 and 21 documented genes in the sheep genome. Most of these genes were previously associated in literature with reproduction related, as well as with growth related traits in various farm animal species. This study, supported by results from previous studies performed on sheep and cattle, identified the following genes that warrant further investigation as to their functions and processes relating to growth and reproduction in sheep: MAP7D1, TRAPPC3, THRAP3, TRMP8, SPP2, HDAC9, ZFHX3, SIX6, C14orf39, TAF4B, TRSP1 EYA2, RBMS3, STL38L, BSPH1, LIG1, CABP5 and ELSPBP1. Conclusions: Long-term selection in the flocks for both body weight and reproductive traits, and especially on the composite trait TWW, have favoured genes with pleiotropic effects influencing both groups of traits. SNPs associated with these pleiotropic genes were detected in the association analyses for the various traits.


2013 ◽  
Vol 29 (2) ◽  
pp. 277-286 ◽  
Author(s):  
Zoran Ilic ◽  
A. Jevtic-Vukmirovic ◽  
M.P. Petrovic ◽  
V. Caro-Petrovic ◽  
B. Milosevic ◽  
...  

Estrus synchronization methods was use to control the reproductive traits of sheep, as well as bringing more females at the same stage of estrus and ovulation. According to the points mentioned above, the aim of the present study was to investigate and compare mating method and influence of fixed factors on birth and weaning weight of lambs. Statistical analysis showed that exist difference in the body weights between genotypes of lambs. In the first group, the difference in weight of lambs at birth, regardless of mating method was not significant (P> 0.05), while in the second group, the difference was slightly significant (P <0.05). As for the birth type, sex and within the same genotype, there was a statistical significance (P <0.05) between singles obtained naturally, between the triplets obtained naturally and between triplets received hormonal method. All the differences between body weight at 30 days (mating method, sex and birth type under the same genotype) were statistically significant (P <0.05).The determined differences in the body weights at 60 days (sex, mating method and type of birth under the same genotype) were statistically significant (P <0.05). The results showed that the differences (mating method, sex and type of birth under the same genotype) were statistically significant (P <0.05), except in between body weight at 90 days in twins among two genotypes obtained by natural method, which were not statistically significant (P> 0.05).


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