Antimicrobial activities of Moringa oleifera Lam leaf extracts

2012 ◽  
Vol 11 (11) ◽  
Author(s):  
Moyo
Keyword(s):  
Moringa Oleifera ◽  
Antimicrobial Activities ◽  
Leaf Extracts ◽  
Moringa Oleifera Lam

scholarly journals Phytochemical screening of Moringa oleifera leaf extracts and their antimicrobial activities

2020 ◽  
Vol 66 (1) ◽  
pp. 20
Author(s):  
Gholamreza Bagheri ◽  
Miquel Martorell ◽  
Karina Ramírez-Alarcón ◽  
Bahare Salehi ◽  
Javad Sharifi-Rad
Keyword(s):  
Moringa Oleifera ◽  
Antimicrobial Activities ◽  
Phytochemical Screening ◽  
Leaf Extracts

scholarly journals The effect of 2-hydroxypropyl β-cyclodextrin on the stability of polyphenolic compounds from Moringa oleifera Lam leaf extracts in a natural low-transition temperature mixture

2018 ◽  
Vol 17 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Ioanna Karageorgou ◽  
Spyros Grigorakis ◽  
Stavros Lalas ◽  
Dimitris P. Makris
Keyword(s):  
Transition Temperature ◽  
Moringa Oleifera ◽  
Protective Action ◽  
Leaf Extracts ◽  
Decay Constants ◽  
Slowing Down ◽  
First Order Kinetics ◽  
Quercetin Glycosides ◽  
The Stability ◽  
Moringa Oleifera Lam

Abstract Polyphenol extracts from Moringa oleifera leaves (MoL) were obtained with a glycerol-based low-transition temperature mixture (LTTM) and a combination of LTTM with 2-hydroxypropyl β-cyclodextrin (HP-β-CD). The extracts were maintained at 4, 22 and 50 °C for 18 days and the antiradical activity (AAR) was recorded to detect modifications in the antioxidant activity of the extracts. AAR displayed a constant decline at every temperature tested, following pseudo first-order kinetics and the decay constants suggested that the presence of HP-β-CD had a protective action, slowing down AAR decline. The analysis of the polyphenolic profiles using liquid chromatography-diode array-mass spectrometry revealed that after storage for 18 days at 50 °C, the major quercetin glycosides occurring in MoL were extensively degraded. Based on the detection of protocatechuic acid in the stored extracts, putative pathways of flavonol glycoside degradation were proposed. It was concluded that the decomposition of these components was mainly responsible for the AAR decline observed.

scholarly journals Phytochemical Analyses, Antioxidant and Anticancer Activities of Ethanolic Leaf Extracts of Moringa oleifera Lam. Varieties

Plants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2348
Author(s):  
Bilques Farooq ◽  
Bhupendra Koul ◽  
Deveshi Mahant ◽  
Dhananjay Yadav
Keyword(s):  
Antioxidant Activity ◽  
Moringa Oleifera ◽  
Sugar Content ◽  
Soluble Proteins ◽  
Mature Stage ◽  
Cytotoxic Activities ◽  
Anticancer Activities ◽  
Leaf Extracts ◽  
Anticancer Compounds ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. (Moringaceae) is revered as s ‘miracle tree’ due to its remarkable nutritional, medicinal and industrial uses. In our study, a comparative analysis of the nutritional parameters (antioxidant activity, sugar content—TSS, total soluble proteins—TSP and mineral contents), phytochemicals (HPLC analysis of four anticancer compounds), and cytotoxicity of M. oleifera leaf extracts (MLEs) of five selected varieties (conventional, PKM-1, PKM-2, ODC, and Jaffna), was performed. Jaffna variety possessed the highest antioxidant activity (FRAP) followed by other four varieties. The trend observed was: Jaffna (9.47 µg/mL, 18.48 µg/mL, 29.39 µg/mL, and 35.37 µg/mL) > PKM-1 (4.82 µg/mL, 7.63 µg/mL, 22.33 µg/mL, and 27.71 µg/mL) > PKM-2 (2.10 µg/mL, 7.04 µg/mL, 13.18 µg/mL, and 21.78 µg/mL) > ODC (0.17 µg/mL, 2.10 µg/mL, 4.41 µg/mL and 13.94 µg/mL) > Conventional (0.05 µg/mL, 1.08 µg/mL, 2.86 µg/mL, and 5.40 µg/mL), total soluble proteins (TSP) [0.69 ± 0.01 and 0.94 ± 0.01 µg/mL (young and mature stage, respectively)], sugar content (TSS) [0.39 ± 0.01 and 0.51 ± 0.01 µg/mL (young and mature stage, respectively)], chlorophyll content [1.07 ± 0.01 (plantlet stage), 1.36 ± 0.003 (vegetative-stage), 0.82 ± 0.004 (reproductive stage) mg/g], followed by the other four varieties. The trend observed for cytotoxic activities of ethanolic MLEs on HepG2 cell line, based on the IC50 values, was conventional (1.22 mg/mL) > ODC (0.90 mg/mL) > PKM-2 (0.65 mg/mL) > PKM-1 (0.35 mg/mL) > Jaffna (0.15 mg/mL). The results of HPLC quantification of anticancer compounds [beta-sitosterol (0.244%), quercetin (0.216%), kaempferol (0.013%), and moringin (0.063%)] was also in consonance with that of MTT assay. In summary, the trend observed in all the parameters tested was Jaffna > PKM-1 > PKM-2 > ODC > conventional. Thus, Jaffna variety has a better potential to combat malnutrition and cancer and must be recommended for commercial plantations.

scholarly journals Effect of extraction methods on physicochemical, nutritional, antinutritional, antioxidant and antimicrobial activity of Moringa (Moringa oleifera Lam.) seed kernel oil

2018 ◽  
Vol 10 (1) ◽  
pp. 287-295 ◽  
Author(s):  
B. L. Dinesha ◽  
Udaykumar Nidoni ◽  
C. T. Ramachandra ◽  
Nagaraj Naik ◽  
K.B. Sankalpa
Keyword(s):  
Moringa Oleifera ◽  
Antioxidant Activities ◽  
Soxhlet Extraction ◽  
Extraction Methods ◽  
Antimicrobial Activities ◽  
Nutritional Composition ◽  
Seed Kernel ◽  
Kernel Oil ◽  
Physico Chemical ◽  
Moringa Oleifera Lam

The effect of three different extraction methods, namely supercritical CO2, soxhlet and solvent methods on the yield, efficiency, physico-chemical properties, nutritional, anti-nutritional composition, antimicrobial and antioxidant activities of moringa (Moringa oleifera Lam.) seed kernel oil was investigated in this study. Oil extraction for SC-CO2 were 37.76 g/100g and 98.43%, observed to be higher than those of soxhlet extraction (29.12 g/100g and 76.29%), and significantly lower than solvent extraction (22.12 g/100g and 57.99%). The physico-chemical composition of the oils showed considerable variation among the extraction methods. The SC-CO2 extracted oil was found to be of superior quality, showing negligible thermal degradation and exhibited significantly (p<0.01) higher nutritional and antioxidant activity and lower anti-nutritional composition than the soxhlet and solvent extracted oils. Oils produced by SC-CO2 and soxhlet extraction methods had antimicrobial activities higher than solvent extracted oil. SCCO2 extracted oil was found to have maximum number of bioactive compounds (14 compounds) followed by solvent (8 compounds) and soxhlet (4 compounds) extracted oil. The results of the study demonstrated that SC-CO2 would be a promising process for the extraction of moringa seed kernel oil of premium quality.

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