scholarly journals Heart failure: role of cardiovascular imaging

Medwave ◽  
2016 ◽  
Vol 16 (Suppl4) ◽  
pp. e6552-e6552 ◽  
Author(s):  
Rienzi Díaz Navarro
Keyword(s):  
Heart Failure ◽  
Cardiovascular Imaging

scholarly journals Phase II trials in heart failure: The role of cardiovascular imaging

2011 ◽  
Vol 162 (1) ◽  
pp. 3-15.e3 ◽  
Author(s):  
Sanjiv J. Shah ◽  
Gregg C. Fonarow ◽  
Mihai Gheorghiade ◽  
Roberto M. Lang
Keyword(s):  
Heart Failure ◽  
Phase Ii ◽  
Cardiovascular Imaging ◽  
Phase Ii Trials

Protective role of peroxiredoxin-4 in heart failure

2020 ◽  
Vol 134 (1) ◽  
pp. 71-72
Author(s):  
Naseer Ahmed ◽  
Masooma Naseem ◽  
Javeria Farooq
Keyword(s):  
Heart Failure ◽  
Cardiac Fibroblasts ◽  
Protective Role ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Galectin 3 ◽  
Consequent Increase ◽  
And Oxidative Stress

Abstract Recently, we have read with great interest the article published by Ibarrola et al. (Clin. Sci. (Lond.) (2018) 132, 1471–1485), which used proteomics and immunodetection methods to show that Galectin-3 (Gal-3) down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers in cardiac fibroblasts.’ We would like to point out some results stated in the article that need further investigation and more detailed discussion to clarify certain factors involved in the protective role of Prx-4 in heart failure.

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