scholarly journals Applying Central Composite Design and Response Surface Methodology to Optimize Growth and Biomass Production of Haemophilus influenzae Type b

2016 ◽  
Vol 9 (6) ◽  
Author(s):  
Seyed Bahman Momen ◽  
Seyed Davar Siadat ◽  
Neda Akbari ◽  
Bijan Ranjbar ◽  
Khosro Khajeh
Keyword(s):  
Response Surface Methodology ◽  
Haemophilus Influenzae ◽  
Central Composite Design ◽  
Response Surface ◽  
Biomass Production ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Central Composite

scholarly journals Plackett-Burman matrix and response surface methodology-central composite design for optimization of Lactobacillus Acidophilus biomass production

2014 ◽  
Vol 17 (2) ◽  
pp. 60-72
Author(s):  
Huong Huynh Lien Ly ◽  
Huong Thuy Nguyen
Keyword(s):  
Response Surface Methodology ◽  
Central Composite Design ◽  
Response Surface ◽  
Biomass Production ◽  
Lactobacillus Acidophilus ◽  
Initial Density ◽  
Optimization Theory ◽  
Similar Proportion ◽  
Maximum Value ◽  
Central Composite

Biomass of Lactobacillus acidophilus was optimized in the tofu wastewater medium by Plackett-Burman matrix and Response surface methodology – Central composite design (RSM-CCD). The highest biomass was 0.73 g/100mL at 106 CFU/mL of initial density of L. acidophilus in tofu wastewater medium, with 0.37% (NH4)2SO4 and 17.59% sucrose. L. acidophilus produced maximum value of biomass after 20 hours of incubation at 37°C. There was a similar proportion at 96.05% in comparison to experimental value and optimization theory, approximatly 93.58% L. acidophilus biomass in MRS medium. As a result, optimization model could be applied in biomass production of L. acidophilus to enhance comercial value and contribute to environmental protection.

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