scholarly journals Association of Matrix Metalloproteinase-1 -1607 1G/2G and C-Reactive Protein -717 C/T Gene Polymorphisms in Iranian Patients with Chronic Periodontitis: A Clinical Trial

2019 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Surena Vahabi ◽  
Bahareh Nazemisalman ◽  
Mahsa Kalantari ◽  
Sepanta Hosseinpour
Keyword(s):  
Clinical Trial ◽  
Matrix Metalloproteinase ◽  
Chronic Periodontitis ◽  
Gene Polymorphisms ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Matrix Metalloproteinase 1 ◽  
Iranian Patients

scholarly journals C-Reactive Protein Induces Matrix Metalloproteinase-1 and -10 in Human Endothelial Cells

2006 ◽  
Vol 47 (7) ◽  
pp. 1369-1378 ◽  
Author(s):  
Ines Montero ◽  
Josune Orbe ◽  
Nerea Varo ◽  
Oscar Beloqui ◽  
José I. Monreal ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Matrix Metalloproteinase ◽  
Human Endothelial Cells ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Matrix Metalloproteinase 1

scholarly journals Impact of Matrix Metalloproteinase-9 during Periodontitis and Cardiovascular Diseases

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1777
Author(s):  
Gaetano Isola ◽  
Alessandro Polizzi ◽  
Vincenzo Ronsivalle ◽  
Angela Alibrandi ◽  
Giuseppe Palazzo ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Healthy Subjects ◽  
Multivariate Regression Analysis ◽  
Matrix Metalloproteinase 9 ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Hs Crp ◽  
The Impact ◽  
Negative Predictor ◽  
Metalloproteinase 9

Matrix metalloproteinase-9 (MMP-9) has been shown to play a key role in endothelial function and perhaps pivotal in the correlation between periodontal disease and cardiovascular disease (CVD). For the study, the impact of MMP-9 of periodontitis and CVD on serum and saliva concentrations was analyzed. For the study patients with periodontitis (n = 31), CVD (n = 31), periodontitis + CVD (n = 31), and healthy patients (n = 31) were enrolled. Clinical and demographic characteristics as well as serum and salivary MMP-9 were evaluated. MMP-9 concentrations in serum and saliva were statistically elevated in patients with CVD (p < 0.01) and in patients with periodontitis plus CVD (p < 0.001) compared to patients with periodontitis and healthy subjects. Multivariate regression analysis showed that c-reactive protein (hs-CRP) was the only significant predictor for MMP-9 serum (p < 0.001), whereas hs-CRP (p < 0.001) and total cholesterol (p = 0.029) were the statistically significant salivary MMP-9 predictors. This study evidenced that patients with CVD and periodontitis + CVD presented elevated MMP-9 concentrations in serum and saliva compared to patients with periodontitis and healthy subjects. Furthermore, hs-CRP was a negative predictor of serum and salivary MMP-9.

scholarly journals Chronic Periodontitis and C-Reactive Protein Levels

2011 ◽  
Vol 82 (7) ◽  
pp. 969-978 ◽  
Author(s):  
Isaac Suzart Gomes-Filho ◽  
Julita Maria Freitas Coelho ◽  
Simone Seixas da Cruz ◽  
Johelle Santana Passos ◽  
Camila Oliveira Teixeira de Freitas ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

scholarly journals A COMPARATIVE EVALUATION OF C-REACTIVE PROTEIN GCF LEVEL IN PERIODONTITIS PATIENTS AFTER SCALING AND ROOT PLANING WITH AND WITHOUT DIODE LASER

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Sangeeta Roy ◽  
C.S. Joshi ◽  
Pradeep Shukla ◽  
Gaurav Malhotra ◽  
Prerna Kataria ◽  
...  
Keyword(s):  
Diode Laser ◽  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Type I ◽  
Scaling And Root Planing ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Root Planing ◽  
Crevicular Fluid

Background and Objectives: C?reactive protein (CRP) is a type I acute phase reactant. A number of studies have reported elevated gingival crevicular fluid (GCF) CRP levels in periodontitis subjects, which decrease following periodontal therapy. Effect of diode laser as an adjuct to Scaling & Root planing is also well stablished. The aim of the present study was to evaluate the effect of periodontal treatment SRP with diode laser, on CRP levels in GCF in patients with chronic periodontitis. Materials and Methods: A total of 40 subjects with moderate periodontitis based on community periodontal index scores, were included in the study. Periodontal therapy was performed dividing each side of jaw as a group (Split mouth); one side SRP alone & another Diode laser with SRP. GCF was collected from each subject at Baseline (prior to treatment) and 1 month after periodontal therapy. The collected sample was subjected to biochemical analysis to detect CRP levels by using a commercially available highly sensitive kit. Results: The present study demonstrated that the mean CRP values at baseline were found to be 0.11043mg/l in side-I (side treated with SRP alone); 0.11042mg/l in side-II (side treated with SRP & laser) of the patient, which reduced to 0.4148 mg/L in side I and 0.3985mg/L in side II after treatment, which are highly significant according to statistical analysis but the changes between two sides were non- significant statistically. Interpretation and Conclusion: Within the limitations of this study, it can be concluded that periodontal therapy is able to reduce the GCF C reactive protein level significantly, but there was no statistically significant result in CRP level, between sides treated with SRP & SRP with laser. Key words: Chronic periodontitis, C?reactive protein, gingival crevicular fluid, Scaling and root planing, Diode laser

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