scholarly journals Chronic Periodontitis and C-Reactive Protein Levels

2011 ◽  
Vol 82 (7) ◽  
pp. 969-978 ◽  
Author(s):  
Isaac Suzart Gomes-Filho ◽  
Julita Maria Freitas Coelho ◽  
Simone Seixas da Cruz ◽  
Johelle Santana Passos ◽  
Camila Oliveira Teixeira de Freitas ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

SEVERE CHRONIC PERIODONTITIS AND C-REACTIVE PROTEIN LEVELS

2017 ◽  
Vol 6 (2) ◽  
pp. 1
Author(s):  
Johelle De Santana Passos Soares ◽  
Isaac Suzart Gomes-Filho ◽  
Julita Maria Freitas Coelho ◽  
Simone Seixas da Cruz ◽  
Luís Claúdio Lemos Correia ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Descriptive Analysis ◽  
Cross Sectional Study ◽  
Blood Collection ◽  
C Reactive Protein ◽  
Clinical Attachment Loss ◽  
Cross Sectional ◽  
Protein Levels ◽  
Reactive Protein ◽  
Significant Difference

This study aims to analyze the relationship between chronic periodontitis and C-reactive protein (CRP), taking certain associated factors into consideration. A cross-sectional study was conducted on a sample of 75 adults of both sexes. After the participants had been interviewed, they underwent physical and dental examinations and blood collection. CRP levels were evaluated by means of nephelometry. A periodontal clinical examination was conducted by trained examiners and the diagnosis of chronic periodontitis was established when at least 30% of the individual’s teeth presented clinical attachment loss ≥ 5 mm. The analysis procedures consisted of descriptive analysis and linear regression. The results showed that there was no statistically significant difference in CRP levels between the groups with and without periodontitis. The median CRP level in the group with periodontitis was 2.3 mg/l (25-75% interquartile range, IQR = 0.74-5.4) and in the group without periodontitis, 1.8 mg/l (25-75% IQR = 0.79-4.54) (p = 0.417). Log CRP was significantly correlated only with the individual’s body mass index (BMI). The main findings from this study indicate that there is no association between severe chronic periodontitis and CRP, and factors like BMI need to be analyzed carefully in studies on this topic.

scholarly journals The Effect of Non Surgical Periodontal Therapy on the Serum C Reactive Protein Levels in Generalized Chronic Periodontitis Patients: A Clinical Study

2014 ◽  
Vol 02 (03) ◽  
pp. 157-161
Author(s):  
Anish Manocha ◽  
Suresh DK ◽  
Shikha Gupta ◽  
Sharuti Yakhmi ◽  
Aashish Pandit
Keyword(s):  
Chronic Periodontitis ◽  
Inflammatory Markers ◽  
Serum Levels ◽  
Periodontal Therapy ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Serum Crp ◽  
Age Range

Abstract Background: Although many studies have compared circulating IL-6 and CRP concentrations in periodontal patients and controls, a limited number of studies have compared systemic inflammatory markers at baseline and follow-up and also Data on whether periodontal therapy affects serum CRP levels are inconclusive. Aims and Objective: By the virtue of this study, an attempt was made to evaluate and compare the effect of non surgical periodontal therapy on serum C-Reactive Protein levels in Generalized chronic periodontitis patients. Material and Method: A total of thirty patients with Generalised chronic periodontitis, within the age range of 30-70 years, were selected and underwent non surgical periodontal therapy. Further, they were put on a two month follow up after post operative phase for evaluation and comparison of pre and post values. Results and Conclusion: The results of our study showed that non surgical periodontal therapy significantly reduces the serum levels of C-reactive protein along with other clinical parameters in patients with generalised chronic periodontitis.

scholarly journals Effect of Periodontal Therapy on Serum C-Reactive Protein Levels in Patients with Gingivitis and Chronic Periodontitis: A Clinicobiochemical Study

2013 ◽  
Vol 14 (2) ◽  
pp. 233-237 ◽  
Author(s):  
Veena A Patil ◽  
Manthan H Desai
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Elevated Serum ◽  
Periodontal Therapy ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Potential Biomarker ◽  
Periodontal Index ◽  
Serum Crp

ABSTRACT Aim The aim of the present study was to evaluate the effect of periodontal therapy on serum C-reactive protein (CRP) levels in patients with gingivitis and chronic periodontitis. Materials and methods A total of 60 subjects (30 males and 30 females) were included in the study with 20 subjects in each of the groups classified based on community periodontal index (CPI) scores: I: Healthy, II: Gingivitis, III: Mild periodontitis. Periodontal therapy was performed on groups II and III patients. Venous blood was collected from each subject at baseline and 3 months after periodontal therapy. The collected sample was subjected to biochemical analysis to detect CRP levels by using immunoturbidimetric method. Results The present study demonstrated that the periodontitis group had a higher mean CRP levels (2.49 ± 0.47 ng/ml) as compared to the gingivitis group (1.40 ± 0.32 ng/ml) and healthy group (0.56 ± 0.20 ng/ml). The mean CRP values after periodontal therapy were found to be reduced to 0.44 ± 0.23 ng/ml in group II and 1.30 ± 0.36 ng/ml in group III patients. Conclusion Within the limitations of this study, it can be concluded that CRP level progressively increases from periodontal health to disease. A decrease in CRP levels with periodontal treatment was also observed. Clinical significance Due to its opsonizing abilities CRP plays an important role in the innate host defence. It can be hypothesized that CRP is a potential biomarker of periodontal disease. A number of studies have reported elevated serum CRP levels in periodontitis subjects. Long standing periodontal disease and raised CRP levels enhance the risk of cardiovascular disease, cerebrovascular accidents and preterm low birth weight infants. There is also evidence that effective periodontal therapy can lower serum CRP levels. However, the data of interventional studies on CRP in gingivitis and periodontitis is scarce. How to cite this article Patil VA, Desai MH. Effect of Periodontal Therapy on Serum C-Reactive Protein Levels in Patients with Gingivitis and Chronic Periodontitis: A Clinicobiochemical Study. J Contemp Dent Pract 2013;14(2):233-237.

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