The Effect of 17α-Hydroxyprogesterone Caproate on Prevention of Preterm Labor in High-Risk Pregnant Women

2016 ◽  
Vol 18 (2) ◽  
Author(s):  
Shole Shahgheibi ◽  
Nazli Hamrah ◽  
Nasrin Soofizadeh ◽  
Aidin Mojtahedzadeh ◽  
Fariba Seyedoshohadaei ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Preterm Labor ◽  
Hydroxyprogesterone Caproate

scholarly journals Effects of the Unpleasant Symptom-Relief Program on Preterm Labor Stress, Anxiety, Physical Discomfort, and Situational Discomfort among Hospitalized High-Risk Pregnant Women: A Nonrandomized Controlled Trial

2021 ◽  
Vol 25 (4) ◽  
pp. 269-281
Author(s):  
Guy Nam Kim ◽  
Eun-Young Jun
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Repeated Measures ◽  
Preterm Labor ◽  
Symptom Relief ◽  
T Test ◽  
Control Group ◽  
Physical Discomfort ◽  
Labor Stress ◽  
Relief Program

Purpose: This study aimed to develop and evaluate the effects of the Unpleasant Symptom-Relief Program to mitigate preterm labor stress, anxiety, physical discomfort, and situational discomfort in hospitalized high-risk pregnant women.Methods: This study used a nonequivalent control group nonsynchronized design and analyzed 23 participants from the experimental group and 23 from the control group. The participants from both the groups were matched and diagnosed with preterm labor, incompetent internal os of the cervix, preterm premature rupture of membrane, placenta previa, or gestational diabetes mellitus. The effects of the Unpleasant Symptom-Relief Program were measured using tools such as preterm labor stress, anxiety, physical discomfort, and situational discomfort. The data were analyzed with IBM SPSS Statistics ver. 21.0 using descriptive statistics, t-test, chi-square test, paired t-test, and repeated measures analysis of variance.Results: The Unpleasant Symptom-Relief Program was effective in reducing preterm labor stress (F= 8.24, p=0.001), anxiety (F=17.80, p≤0.001), and situational discomfort (F=5.95, p=0.004). However, it was not effective in reducing the physical discomfort (F=1.20, p=0.311). Post hoc analysis between time points revealed effective reduction in the preterm labor stress and anxiety in both the groups immediately after the end of the program and at 7 days after the program. Situational discomfort was reduced at 7 days after the end of the program in both the groups.Conclusion: The Unpleasant Symptom-Relief Program can be applied in practice by nurses. It can contribute to alleviating the symptoms and discomfort of high-risk pregnant women.

scholarly journals RELATIONSHIP BETWEEN PREGNANT WOMEN'S HIGH-RISK AGE WITH THE PRETERM OF LABOR IN BIDAN PRAKTIK MANDIRI (BPM) BIDAN NANIK SUWATI, AMD. KEB, PUNGGING VILLAGE, MOJOSARI SUB-DISTRICT, MOJOKERTO DISTRICT

2018 ◽  
Vol 7 (2) ◽  
pp. 141-147
Author(s):  
Siti Fithrotul Umami ◽  
Titiek Idayanti
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Preterm Labor ◽  
Secondary Data ◽  
Statistical Test ◽  
Chi Square ◽  
Control Approach ◽  
A Value ◽  
Term Delivery ◽  
Sample Technique

Background. High-risk age for pregnant women is < 20 or > 35 years, the possibility of a bad pregnancy / complications will increase, such as preterm labor. Premature birth is the main cause in almost 2/3 of births. Preterm labor is a labor that occurs in pregnancy between 28 - 37 weeks. The incidence in BPM Bidan Nanik Suwati, Pungging Village, Mojosari Sub-District, which is from 80 women giving birth, found 7 respondents experienced preterm labor including 4 (57.14%) aged <20 and> 35 years and 3 (42.86%) aged 20 - 30 years.Objectives. The purpose of this study was to determine the correlation between pregnant women's high-risk age with the preterm of labor in Bidan Praktik Mandiri (BPM) Bidan Nanik Suwati, Amd. Keb, Pungging Village, Mojosari Sub-District, Mojokerto District.Methods. The research method used is analytic correlation with a case control approach using research instruments in the form of secondary data. The sample technique used in this study was total sampling, so the sample of the study was all pregnant women of high-risk age in BPM Nanik Suwati, Pungging Village, Mojosari Sub-District at 68 respondents. The results of data collection were processed by chi-square statistical test (X2) with a significance distance of α = 0.05.Results. From the results of the study, almost half (31%) of respondents experienced preterm labor and most (69%) of respondents experienced term delivery. Shows a significant relationship between the age of high-risk pregnant women with the incidence of preterm labor with a value of P = 0.036.Conclusion. The factors that influence preterm labor, such as parity, frequency of ANC patients, and obstetric complications. Therefore, it should be recommended for mothers as much as possible not to become pregnant at a high-risk age, namely age <20 and> 35 years. Keywords:      High Risk Age, Pregnant Women, Preterm Labor Incidence.

scholarly journals Effects of nonpharmacological interventions on the psychological health of high-risk pregnant women: a systematic review and meta-analysis

2021 ◽  
Vol 27 (3) ◽  
pp. 180-195
Author(s):  
Hyeji Yoo ◽  
Sukhee Ahn
Keyword(s):  
Systematic Review ◽  
High Risk ◽  
Gestational Diabetes ◽  
Pregnant Women ◽  
Psychological Health ◽  
Preterm Labor ◽  
Meta Analysis ◽  
Current Evidence ◽  
Trim And Fill ◽  
Fail Safe

Purpose: This study aimed to summarize the current evidence on the effects of nonpharmacological interventions on psychological health outcomes for women with high-risk pregnancies due to conditions such as preeclampsia, gestational diabetes, or preterm labor.Methods: The following databases were searched from January 2000 to December 2020: PubMed, Ovid Embase, CINAHL, Web of Science, DBpia, RISS, and KISS. Two investigators independently reviewed and selected articles according to the inclusion/exclusion criteria. RoB 2 and the ROBINS-I checklist were used to evaluate study quality.Results: Twenty-nine studies with a combined total of 1,806 pregnant women were included in the systematic review and meta-analysis. Psychological health improvements were found in women with preeclampsia (Hedges’ g=–0.67; 95% confidence interval [CI], –0.91 to –0.44), gestational diabetes (Hedges’ g=–0.38; 95% CI, –0.54 to –0.12), and preterm labor (Hedges’ g=–0.73; 95% CI, –1.00 to –0.46). The funnel plot was slightly asymmetrical, but the fail-safe N value and the trim-and-fill method showed no publication bias.Conclusion: Nonpharmacological interventions for women with high-risk pregnancies due to conditions such as preeclampsia, gestational diabetes, and preterm labor can improve psychological parameters such as anxiety, stress, and depression. Nurses can play a pivotal role in the nursing management of pregnant women with high-risk conditions and apply various types of nonpharmacological interventions to meet their needs in uncertain and anxious times during pregnancy.

scholarly journals Cervical Length Measurement in Obstetrics: From Academic Luxury to Clinical Practice

2012 ◽  
Vol 6 (1) ◽  
pp. 93-96
Author(s):  
Badreldeen Ahmed ◽  
Zohra Hasnani
Keyword(s):  
Clinical Practice ◽  
Preterm Birth ◽  
High Risk ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Preterm Labor ◽  
Cervical Length ◽  
Length Measurement ◽  
Cervical Length Measurement

ABSTRACT Preterm birth is the main cause of perinatal mortality and morbidity and can be very costly to the healthcare system. Although improvements in neonatal care have led to higher survival of very premature infants, there is a need for the development of a sensitive method with which to identify women at high risk of preterm delivery and find an effective strategy for the prevention of preterm labor.1 Considering the increased incidence of preterm birth, it has become more important now to be able to early diagnose this problem. The measurement of cervical length to predict the risk of preterm birth can be extremely useful in diagnosing this condition. The use of transvaginal ultrasound in measuring cervical length is safe, reliable and well accepted by women.2 The use of vaginal progesterone has shown to be effective in the prevention of preterm delivery in women with short cervix. Tocolytics are used to delay labor for a minimum of 24 to 48 hours3 for up to 1 week but they have not shown to improve neonatal outcomes and most have undesirable side effects. Steroids can assist with fetal lung maturity when the diagnosis of preterm labor is made,3 they can be used unnecessarily when preterm labor is misdiagnosed. The measurement of cervical length can also be helpful in patients with preterm premature rupture of membrane and in patients with the presence of amniotic fluid (AF) sluge.4 Therefore, performing cervical length measurements in all pregnant women and use it as a screening tool at around 20 weeks of pregnancy to identify patients at high risk of preterm labor can assist with true diagnosis. There is a great expectation from cervical assessment and subsequent addition of progesterone to reduce preterm birth and have better neonatal outcomes. The aim of this review is to bring forward evidence that highlights the importance of performing cervical length measurement in midpregnancy in all pregnant women to predict the risk of preterm birth. Medline, PubMed, MD Consult and Science Direct were searched using the terms cervical length measurement, ‘preterm delivery’, ‘amniotic fluid sludge’ and ‘treatment for preterm birth’. How to cite this article Ahmed B, Hasnani Z. Cervical Length Measurement in Obstetrics: From Academic Luxury to Clinical Practice. Donald School J Ultrasound Obstet Gynecol 2012;6(1):93-96.

Dual and multiple trisomies: analysis of 38 cases from 13 thousand karyotyped embryos and fetuses

2017 ◽  
pp. 109-115
Author(s):  
N.P. Veropotvelyan ◽  
Keyword(s):  
Prenatal Diagnosis ◽  
High Risk ◽  
Pregnant Women ◽  
Maternal Age ◽  
Chromosomal Abnormalities ◽  
Chorionic Villus ◽  
Primary Group ◽  
Chorionic Villus Sampling ◽  
Missed Abortion ◽  
Reproductive Losses

The study presents data of different authors, as well as its own data on the frequency of multiple trisomies among the early reproductive losses in the I trimester of pregnancy and live fetuses in pregnant women at high risk of chromosomal abnormalities (CA) in I and II trimesters of gestation. The objective: determining the frequency of occurrence of double (DT) and multiple trisomies (MT) among the early reproductive losses in the I trimester of pregnancy and live fetuses in pregnant women at high risk of occurrence of HA in I and II trimesters of gestation; establishment of the most common combinations of diesel fuel and the timing of their deaths compared with single regular trisomy; comparative assessment materinskogo age with single, double and multiple trisomies. Patients and methods. During the period from 1997 to 2016, the first (primary) group of products in 1808 the concept of missed abortion (ST) of I trimester was formed from women who live in Dnepropetrovsk, Zaporozhye, Kirovograd, Cherkasy, Kherson, Mykolaiv regions. The average term of the ST was 8±3 weeks. The average age of women was 29±2 years. The second group (control) consisted of 1572 sample product concepts received during medical abortion in women (mostly residents of Krivoy Rog) in the period of 5-11 weeks of pregnancy, the average age was 32 years. The third group was made prenatally karyotyped fruits (n = 9689) pregnant women with high risk of HA of the above regions of Ukraine, directed the Centre to invasive prenatal diagnosis for individual indications: maternal age, changes in the fetus by ultrasound (characteristic malformations and echo markers HA) and high risk of HA on the results of the combined prenatal screening I and II trimesters. From 11 th to 14 th week of pregnancy, chorionic villus sampling was performed (n=1329), with the 16th week – platsentotsentez (n=2240), 18 th and 24 th week – amniocentesis (n=6120). Results. A comparative evaluation of maternal age and the prevalence anembriony among multiple trisomies. Analyzed 13,069 karyotyped embryonic and fetal I-II trimester of which have found 40 cases of multiple trisomies – 31 cases in the group in 1808 missed abortion (2.84% of total HA), 3 cases including 1 572 induced medabortov and 7 cases during 9689 prenatal research (0.51% of HA). Determined to share the double trisomies preembrionalny, fetal, early, middle and late periods of fetal development. Conclusion. There were no significant differences either in terms of destruction of single and multiple trisomies or in maternal age or in fractions anembrionalnyh pregnancies in these groups. Key words: multiple trisomies, double trisomy, missed abortion, prenatal diagnosis.

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