How does cerclage compare with no cerclage for preventing preterm birth in pregnant women at high risk for preterm labor/delivery?

2017 ◽  
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Pregnant Women ◽  
Preterm Labor

scholarly journals Cervical Length Measurement in Obstetrics: From Academic Luxury to Clinical Practice

2012 ◽  
Vol 6 (1) ◽  
pp. 93-96
Author(s):  
Badreldeen Ahmed ◽  
Zohra Hasnani
Keyword(s):  
Clinical Practice ◽  
Preterm Birth ◽  
High Risk ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Preterm Labor ◽  
Cervical Length ◽  
Length Measurement ◽  
Cervical Length Measurement

ABSTRACT Preterm birth is the main cause of perinatal mortality and morbidity and can be very costly to the healthcare system. Although improvements in neonatal care have led to higher survival of very premature infants, there is a need for the development of a sensitive method with which to identify women at high risk of preterm delivery and find an effective strategy for the prevention of preterm labor.1 Considering the increased incidence of preterm birth, it has become more important now to be able to early diagnose this problem. The measurement of cervical length to predict the risk of preterm birth can be extremely useful in diagnosing this condition. The use of transvaginal ultrasound in measuring cervical length is safe, reliable and well accepted by women.2 The use of vaginal progesterone has shown to be effective in the prevention of preterm delivery in women with short cervix. Tocolytics are used to delay labor for a minimum of 24 to 48 hours3 for up to 1 week but they have not shown to improve neonatal outcomes and most have undesirable side effects. Steroids can assist with fetal lung maturity when the diagnosis of preterm labor is made,3 they can be used unnecessarily when preterm labor is misdiagnosed. The measurement of cervical length can also be helpful in patients with preterm premature rupture of membrane and in patients with the presence of amniotic fluid (AF) sluge.4 Therefore, performing cervical length measurements in all pregnant women and use it as a screening tool at around 20 weeks of pregnancy to identify patients at high risk of preterm labor can assist with true diagnosis. There is a great expectation from cervical assessment and subsequent addition of progesterone to reduce preterm birth and have better neonatal outcomes. The aim of this review is to bring forward evidence that highlights the importance of performing cervical length measurement in midpregnancy in all pregnant women to predict the risk of preterm birth. Medline, PubMed, MD Consult and Science Direct were searched using the terms cervical length measurement, ‘preterm delivery’, ‘amniotic fluid sludge’ and ‘treatment for preterm birth’. How to cite this article Ahmed B, Hasnani Z. Cervical Length Measurement in Obstetrics: From Academic Luxury to Clinical Practice. Donald School J Ultrasound Obstet Gynecol 2012;6(1):93-96.

Amniotic fluid composition in pregnant women at high risk of preterm birth

2020 ◽  
Vol 8_2020 ◽  
pp. 82-87
Author(s):  
Khodzhaeva Z.S. Khodzhaeva ◽  
Gorina K.A. Gorina ◽  
Muminova K.T. Muminova ◽  
Ivanets T.Yu. Ivanets ◽  
Kessler Yu.V. Kessler ◽  
...  
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Fluid Composition

scholarly journals A Randomized Controlled Open Label Crossover Trial to Study Vaginal Colonization of Orally Administered Lactobacillus Reuteri RC-14 and Rhamnosus GR-1 in Pregnant Women at High Risk for Preterm Labor

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1141 ◽  
Author(s):  
Enav Yefet ◽  
Raul Colodner ◽  
Merav Strauss ◽  
Yifat Gam Ze Letova ◽  
Zohar Nachum
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Bacterial Vaginosis ◽  
Pregnant Women ◽  
Lactobacillus Reuteri ◽  
Bacterial Strains ◽  
Open Label ◽  
Flight Mass Spectrometry ◽  
Vaginal Colonization ◽  
Probiotic Treatment

Lactobacilli administration has been suggested for the treatment and prevention of bacterial vaginosis, which increases the risk for preterm birth. We aimed to evaluate the vaginal colonization of lactobacilli orally administered to pregnant women at risk for preterm birth. We performed a randomized and controlled crossover study between January 2016 and May 2017. Forty pregnant women at high risk for preterm birth with normal vaginal flora (Nugent score ≤ 3) were randomized to either receive two oral capsules/day each containing 5 × 109 Lactobacilli (L.) rhamnosus GR-1 and L. reuteri RC-14 (n = 20) or no treatment (n = 20) for 2 months. Treatments were then crossed over for an additional two months. A vaginal examination and swabbing were performed for assessment of bacterial vaginosis at baseline and every month until study completion. At the same time points, vaginal samples were cultured and subjected to matrix-assisted-laser-desorption/ionization-time-of-flight-mass-spectrometry (MALDI TOF-MS) for the detection of the specific bacterial strains contained in the capsules. The primary endpoint was the presence of the administered lactobacilli strains in the vagina during the first two months of follow-up. Thirty-eight women completed the study. During the first two months of treatment, L. rhamnosus GR-1 was detected in one (5%) woman on the probiotic treatment and 2 (11%) women receiving no treatment (p = 0.6). L. rhamnosus GR-1 was detected in vaginal samples of 4 (11%) women during probiotic treatment (of both groups) and L. reuteri RC-14 was not detected in any samples. The rest of the endpoints were not different between the groups. Altogether, vaginal colonization of lactobacilli following oral administration is low during pregnancy.

scholarly journals Effects of the Unpleasant Symptom-Relief Program on Preterm Labor Stress, Anxiety, Physical Discomfort, and Situational Discomfort among Hospitalized High-Risk Pregnant Women: A Nonrandomized Controlled Trial

2021 ◽  
Vol 25 (4) ◽  
pp. 269-281
Author(s):  
Guy Nam Kim ◽  
Eun-Young Jun
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Repeated Measures ◽  
Preterm Labor ◽  
Symptom Relief ◽  
T Test ◽  
Control Group ◽  
Physical Discomfort ◽  
Labor Stress ◽  
Relief Program

Purpose: This study aimed to develop and evaluate the effects of the Unpleasant Symptom-Relief Program to mitigate preterm labor stress, anxiety, physical discomfort, and situational discomfort in hospitalized high-risk pregnant women.Methods: This study used a nonequivalent control group nonsynchronized design and analyzed 23 participants from the experimental group and 23 from the control group. The participants from both the groups were matched and diagnosed with preterm labor, incompetent internal os of the cervix, preterm premature rupture of membrane, placenta previa, or gestational diabetes mellitus. The effects of the Unpleasant Symptom-Relief Program were measured using tools such as preterm labor stress, anxiety, physical discomfort, and situational discomfort. The data were analyzed with IBM SPSS Statistics ver. 21.0 using descriptive statistics, t-test, chi-square test, paired t-test, and repeated measures analysis of variance.Results: The Unpleasant Symptom-Relief Program was effective in reducing preterm labor stress (F= 8.24, p=0.001), anxiety (F=17.80, p≤0.001), and situational discomfort (F=5.95, p=0.004). However, it was not effective in reducing the physical discomfort (F=1.20, p=0.311). Post hoc analysis between time points revealed effective reduction in the preterm labor stress and anxiety in both the groups immediately after the end of the program and at 7 days after the program. Situational discomfort was reduced at 7 days after the end of the program in both the groups.Conclusion: The Unpleasant Symptom-Relief Program can be applied in practice by nurses. It can contribute to alleviating the symptoms and discomfort of high-risk pregnant women.

scholarly journals The Prevalence of Vaginal Microorganisms in Pregnant Women with Preterm Labor and Preterm Birth

2012 ◽  
Vol 32 (3) ◽  
pp. 194-200 ◽  
Author(s):  
Seong Jin Choi ◽  
Soon Deok Park ◽  
In Ho Jang ◽  
Young Uh ◽  
Anna Lee
Keyword(s):  
Preterm Birth ◽  
Pregnant Women ◽  
Preterm Labor

The Effect of 17α-Hydroxyprogesterone Caproate on Prevention of Preterm Labor in High-Risk Pregnant Women

2016 ◽  
Vol 18 (2) ◽  
Author(s):  
Shole Shahgheibi ◽  
Nazli Hamrah ◽  
Nasrin Soofizadeh ◽  
Aidin Mojtahedzadeh ◽  
Fariba Seyedoshohadaei ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Preterm Labor ◽  
Hydroxyprogesterone Caproate

Metabolomics and preterm birth: What biomarkers in cervicovaginal secretions are predictive of high-risk pregnant women?

2011 ◽  
Vol 307 (1-3) ◽  
pp. 33-38 ◽  
Author(s):  
Christiane Auray-Blais ◽  
Evelyne Raiche ◽  
René Gagnon ◽  
Maryse Berthiaume ◽  
Jean-Charles Pasquier
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Pregnant Women
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