scholarly journals Characterization of Fecal Microbiota, Short-Chain Fatty Acids and Lactic Acid Concentrations in 5 - 8-Year-Old Children with Cow Milk Protein Allergy

2018 ◽  
Vol 28 (4) ◽  
Author(s):  
Yanru Dong ◽  
Peng Fei ◽  
Ying Han ◽  
Ling Guo
Keyword(s):  
Fatty Acids ◽  
Lactic Acid ◽  
Milk Protein ◽  
Short Chain Fatty Acids ◽  
Fecal Microbiota ◽  
Short Chain ◽  
Cow Milk ◽  
Cow Milk Protein Allergy ◽  
Chain Fatty Acids

Variable Effects of Short Chain Fatty Acids and Lactic Acid in Inducing Intestinal Mucosal Injury in Newborn Rats

2002 ◽  
Vol 35 (4) ◽  
pp. 545-550 ◽  
Author(s):  
Jing Lin ◽  
Suhas M. Nafday ◽  
Sara N. Chauvin ◽  
Margret S. Magid ◽  
Sudha Pabbatireddy ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lactic Acid ◽  
Mucosal Injury ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Newborn Rats ◽  
Intestinal Mucosal Injury ◽  
Chain Fatty Acids

scholarly journals Salmonella versus the Microbiome

2020 ◽  
Vol 85 (1) ◽  
pp. e00027-19
Author(s):  
Andrew W. L. Rogers ◽  
Renée M. Tsolis ◽  
Andreas J. Bäumler
Keyword(s):  
Fatty Acids ◽  
Intestinal Inflammation ◽  
Opportunistic Infections ◽  
Short Chain Fatty Acids ◽  
Fecal Microbiota ◽  
Short Chain ◽  
Noncommunicable Diseases ◽  
Colonization Resistance ◽  
Habitat Filtering ◽  
Chain Fatty Acids

SUMMARYA balanced gut microbiota contributes to health, but the mechanisms maintaining homeostasis remain elusive. Microbiota assembly during infancy is governed by competition between species and by environmental factors, termed habitat filters, that determine the range of successful traits within the microbial community. These habitat filters include the diet, host-derived resources, and microbiota-derived metabolites, such as short-chain fatty acids. Once the microbiota has matured, competition and habitat filtering prevent engraftment of new microbes, thereby providing protection against opportunistic infections. Competition with endogenous Enterobacterales, habitat filtering by short-chain fatty acids, and a host-derived habitat filter, epithelial hypoxia, also contribute to colonization resistance against Salmonella serovars. However, at a high challenge dose, these frank pathogens can overcome colonization resistance by using their virulence factors to trigger intestinal inflammation. In turn, inflammation increases the luminal availability of host-derived resources, such as oxygen, nitrate, tetrathionate, and lactate, thereby creating a state of abnormal habitat filtering that enables the pathogen to overcome growth inhibition by short-chain fatty acids. Thus, studying the process of ecosystem invasion by Salmonella serovars clarifies that colonization resistance can become weakened by disrupting host-mediated habitat filtering. This insight is relevant for understanding how inflammation triggers dysbiosis linked to noncommunicable diseases, conditions in which endogenous Enterobacterales expand in the fecal microbiota using some of the same growth-limiting resources required by Salmonella serovars for ecosystem invasion. In essence, ecosystem invasion by Salmonella serovars suggests that homeostasis and dysbiosis simply represent states where competition and habitat filtering are normal or abnormal, respectively.

scholarly journals Isolation and characterization of bacterium producing lipid from short-chain fatty acids

2016 ◽  
Vol 201 ◽  
pp. 215-221 ◽  
Author(s):  
Yoshiko Okamura ◽  
Shota Nakai ◽  
Masahiko Ohkawachi ◽  
Masahiro Suemitsu ◽  
Hirokazu Takahashi ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Isolation And Characterization ◽  
Chain Fatty Acids
Sign in / Sign up

Export Citation Format

Share Document