scholarly journals Gallstone Frequency in Patients with Helicobacter pylori Gastritis

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Behnaz Eslami ◽  
Majid Iranshahi ◽  
Latif Gachkar ◽  
Fahimeh Hadavand

Background: Identification of the causes of gallstone would result in better planning for the prevention of this disease. One of the proposed risk factors for this problem is Helicobacter pylori(H. pylori) infection. Objectives: The purpose of this study was to determine the incidence rate of gallstone in patients with H. pylori gastritis. Methods: This was an observational study performed as a descriptive-comparative cross-sectional survey. We enrolled 169 consecutive patients with H. pylori gastritis admitted to Imam-Hossein Hospital, Tehran, Iran, in 2018, and gallstone frequency in them was determined and compared with other variables. Results: Overall, 14 (8.3%) patients had gallstone, and all the patients had H. pylori gastritis. There was no significant association between gallstone and H. pylori gastritis (P = 0.561). Conclusions: It may be concluded that gallstone frequency in patients with H. pylori gastritis is low, and there is no significant association between these two conditions.

Author(s):  
R. I. Khlynova ◽  
O. M. Khromtsova ◽  
R. B. Berdnikov ◽  
I. B. Khlynov

The aim is to study the effect of Helicobacter pylori infection on risk of developing gastroesophageal reflux disease. Materials and methods - cross-sectional observational study of 1007 patients with dyspepsia syndrome who underwent videoesophagogastroduodenoscopy with biopsy and histological examination of biopsy specimens of the gastric mucosa by OLGA-system. The age, gender, overweight, cigarette smoking, presence of Helicobacter pylori infection and gastritis stage were assessed. Results - the study showed a significant decrease in the incidence of gastroesophageal reflux disease in patients with positive H. Pylori status by 4% (RR 0,68; 95% CI, 0.49-0.94, p=0,041). The risk of developing gastroesophageal reflux disease significantly higher in overweight (RR 2,62; 95% CI 2,0-3,56; р<0,001) men (RR 1,76; 95% CI 1,33-2,32; р=0,0046) who smoked cigarettes (RR 3,23; 95% CI 2,45-4,24; р<0,001) and was not associated with the patient’s age and the stage of gastritis (р>0,05). Conclusion - a significant reduction in the frequency and risk of developing gastroesophageal reflux disease in patients with Helicobacter pylori infection is demonstrated.


2021 ◽  
Vol 3 (4) ◽  
pp. 28-32
Author(s):  
Abel Fils Nkoth ◽  
Christian Ngounouh Taheu ◽  
Angele Clarisse Okono Kabeyene ◽  
Sandra Germaine Gueuma Tchoumbou ◽  
Jean Paul Chedjou ◽  
...  

Background: Helicobacter pylori (H. pylori) infection affects more than half people worldwide particularly in African countries such as Cameroon. This study aimed to investigate the prevalence of H. pylori infection and predictors risk factors among patients undergoing gastro-duodenal fibroscopy at the Centre Medical, la Cathédrale of Yaoundé. Methods: A facility-based descriptive cross-sectional study involving 147 patients was conducted from October 2015 to April 2016. A structured questionnaire was used to collect information on socio-demographic factors and predictors of H. pylori infection. Gastric biopsies specimens were collected from the antrum and corpus using an Olympus GIF – Q30 fully immersible gastroscope respectively. The biopsies were screened for the presence of H. pylori by targeting the glmM gene using polymerase chain reaction (PCR). Statistical analysis was performed using SPSS v. 20 with p-value<0.05 considered statistically significant. Results: The mean age was 47.19 ±16.64 years and female were more represented with 88/147 (59.8%) versus (vs.) 59/147(40.1%) for male. The overall prevalence of H. pylori infection was 50/147 (34.01%; 95% CI: 26.41% - 42.28%). The prevalence of H. pylori infection was 22/59 (37.29%) in male vs. 28/88 (31.82%) in female and this prevalence increased with age and peaked among 30-50 years. Bivariate logistic regression analysis identified that, the regional group, particularly the Centre region (OR 2.55, p= 0.007) and West region (OR 2.67, p=0.005), the level of education (OR 1.18, p=0.001), source of income (OR 0.95, p=0.004), and alcohol consumption (OR 1.41, p=0.0001) were predictors risk factors of H. pylori infection. Conclusions: Our findings indicate a relatively high prevalence of H. pylori infection in Yaoundé. Factors such as regional group, level of education, source of income, and alcohol consumption predisposed the subjects to H. pylori infection.


2017 ◽  
Vol 7 (3) ◽  
Author(s):  
Gasim I. Gasim ◽  
Abdelmageed Elmugabil ◽  
Hamdan Z. Hamdan ◽  
Duria A. Rayis ◽  
Ishag Adam

The objective was to investigate the prevalence and the association between blood groups and <em>Helicobacter pylori</em> IgG seropositivity among pregnant Sudanese women. A cross-sectional survey was carried- out at Saad Abul Ela Maternity Hospital, Khartoum, Sudan during the period of July 2014 through December 2015. Questionnaires covering socio-demographic and obstetrics information were administered. Specific <em>H. pylori</em> IgG antibody was analysed using ELISA. One hundred eighty six pregnant women were enrolled. The mean (SD) of the age, parity was 28.3 (2.6) years and 2.6 (3.5), respectively. Of the 186 women, 42 (22.6%), 24 (12.9%), 11(5.9%) and 109 (58.6%) had blood group A, B, AB and O, respectively. <em>H. pylori</em> IgG seropositivity rate was 132/186 (71.0%). There was no significant difference in age and parity between women with <em>H. pylori</em> IgG seropositive and seronegative. Compared with the women with <em>H. pylori</em> IgG seronegative, significantly higher numbers of women with <em>H. pylori</em> IgG seropositive had O blood group, [84/132(63.6) <em>versus</em> 25/54(46.3), P&lt;0.001]. In binary logistic regression, women with O blood group (OR= 2.084, 95% CI=1.060 -4.097, P=0.033) were at a higher <em>H. pylori</em> IgG seropositivity. The current study showed that women with blood group O were at higher risk for <em>H. pylori</em> IgG seropositivity.


Author(s):  
Okonkwo Lilian Okwubenata ◽  
Musa Bolanle Olufunke Priscilla ◽  
Hali Bello ◽  
Mustapha Shettima Kagu

Background Helicobacter pylori infection is prevalent in African region especially in areas with low socioeconomic status. This study aimed to determine the prevalence and risk factors for Helicobacter pylori Infection among individuals with and those without dyspepsia Materials and Methods The study was cross sectional in which individuals with and those without dyspepsia were enrolled. The prevalence for Helicobacter pylori infection was determined by the screening of Helicobacter pylori immunoglobulin G and this was compared across variables of interest. IBM SPSS was used for the data analysis. Results Overall prevalence of Helicobacter pylori immunoglobulin G was 44 (37.9 %). There was no association between H pylori infection and dyspepsia (0.894). There was statistically significant association between residing in rural areas and acquiring of Helicobacter pylori infection (P= 0.011). Study participants from rural areas had significantly higher and lower pit latrines and water closet toilets respectively than the study participants who reside in urban areas (P= 0.0001). Conclusion Modest prevalence of Helicobacter pylori infection was observed and no association between H pylori infection and dyspepsia was observed. There is a need to take strategic measures towards improving level of socio-economic status of the rural areas so as to reduce the risk of contracting Helicobacter pylori infection in people living in rural areas


Author(s):  
Markos Negash ◽  
Habtamu Wondifraw Baynes ◽  
Demeke Geremew

Background. Helicobacter pylori (H. pylori) is implicated for the causation of gastrointestinal tract infections including gastric cancer. Although the infection is prevalent globally, the impact is immense in countries with poor environmental and socioeconomic status including Ethiopia. Epidemiological study on the magnitude of H. pylori and possible risk factors has priceless implication. Therefore, in this study, we determined the prevalence and risk factors of H. pylori infection in the resource-limited area of northwest Ethiopia. Methods. A prospective cross-sectional study was conducted on northwest Ethiopia among 201 systematically selected dyspeptic patients. Data were collected using a structured and pretested questionnaire, and stool and serum samples were collected and analyzed by SD BIOLINE H. pylori Ag and dBest H. pylori Disk tests, respectively. Chi-square test was performed to see association between variables, and binary and multinomial regression tests were performed to identify potential risk factors. P values <0.05 were taken statistically significant. Result. Prevalence of H. pylori was found to be 71.1% (143/201) and 37.3% (75/201) using the dBest H. pylori Test Disk and SD BIOLINE H. pylori Ag test, respectively. H. pylori seropositivity, using dBest H. pylori Disk tests, is significantly associated in age groups <10 years (P=0.044) and married patients (P=0.016). In those patients with H. pylori (a positive result with either the Ab or Ag test), drinking water from well sources had 2.23 times risk of getting H. pylori infection (P=0.017), and drinking coffee (1.51 (0.79–2.96, P=0.025)) and chat chewing (1.78 (1.02–3.46, P=0.008) are the common risk factors. Conclusion. The present study discovered considerable magnitude of H. pylori among the dyspeptic patients in the study area. H. pylori infection is frequent in individuals drinking water from well sources, and thus, poor sanitation and unhygienic water supply are contributing factors. Policies aiming at improving the socioeconomic status will reduce potential sources of infection, transmission, and ultimately the prevalence and incidence of H. pylori.


2008 ◽  
Vol 11 (3) ◽  
pp. 230-236 ◽  
Author(s):  
Mahmoud A Mohammad ◽  
Laila Hussein ◽  
Andy Coward ◽  
Sarah J Jackson

AbstractObjectiveThe study aim was to assess the prevalence of Helicobacter pylori infection in Egyptian schoolchildren and its effect on growth parameters.DesignA cross-sectional population-based study was conducted among 286 schoolchildren (168 boys and 118 girls), with a mean age of 11.04 ± 0.19 years, to determine the prevalence of H. pylori. The presence of the bacterium was assessed using the [13C]urea breath test. Relevant personal and socio-economic data on risk factors for infection were collected. Height and weight were analysed in relation to H. pylori infection.ResultsThe overall prevalence of H. pylori infection was 72.38%. Attending school in a socially deprived area and residing in an overcrowded home were the major risk factors for infection. Differences between infected and non-infected children were significant with regard to body weight and height (weight: 39.5 ± 1.0 vs. 44.6 ± 1.8 kg, P = 0.05; height: 139.9 ± 1.3 vs. 144.2 ± 2.1 cm; P = 0.009). The number of children (both boys and girls) falling below the 5th percentile of height-for-age was significantly higher in infected than non-infected children (P = 001), similarly for Z-scores for height-for-age below –2.0 (P = 0.003).ConclusionThe results demonstrate not only that the prevalence of H. pylori infection is extremely high among Egyptian schoolchildren, but also that the adverse effects of the infection reach far beyond the stomach. Evidence of the burden of infection on growth failure is presented.


Biology ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 599
Author(s):  
Ghalia Khoder ◽  
Sara Mina ◽  
Ibrahim Mahmoud ◽  
Jibran Sualeh Muhammad ◽  
Rania Harati ◽  
...  

Helicobacter pylori (H. pylori) infection occurs among half of the general population worldwide, with high geographic variability. Even though H. pylori is the leading cause of several gastric diseases, ranging from gastritis and peptic ulcers to gastric malignancies, such as gastric cancer and mucosa-associated lymphoid tissue lymphoma, most of the infections remain asymptomatic. Early detection and eradication of H. pylori can definitely prevent severe long-term gastric diseases associated with H. pylori. In Lebanon, the prevalence of H. pylori is not well documented, especially in healthy subjects. The aim of this study is to assess H. pylori infections and the associated risk factors in Tripoli, North Lebanon. A cross-sectional study was conducted on 300 healthy Lebanese volunteers, including both children and adults. The H. pylori stool antigens were detected using the Premier Platinum HpSA test. The socio-demographic data, lifestyle characteristics, and gastrointestinal characteristics of all participants were analyzed. Out of the 300 tested volunteer subjects, 31% were found to be positive for H. pylori. A multivariate binary logistic regression analysis for factors associated with H. pylori infection revealed a significant association between H. pylori infection and gastrointestinal disturbances, the crowding index, and occupation. A significant statistical correlation was found between sheesha smoking (p = 0.001) and H. pylori infection. These findings highlight the need for the development of preventive approaches and strategic indications for the appropriate treatment of H. pylori infections in Tripoli, North Lebanon.


2019 ◽  
Vol 15 (1) ◽  
pp. 10-16
Author(s):  
Shreyan Kar ◽  
Tushar Kanti Das ◽  
Prasanta Kumar Mohapatra ◽  
Brajaballav Kar ◽  
Anupama Senapati ◽  
...  

Background: While it is apparent that old age is associated with multiple health concerns, the extent of its multiplicity and burden is often not clear. It was intended to find out self-reported health concerns for one month and cardiovascular risk factors in middle and older adults. Methods: In the cross-sectional survey, attendees of a Healthy Ageing Conference were approached with a semi-structured questionnaire about their health concerns and cardiovascular risks. Risk of a cardiovascular event in 10 years based on QRISK3 was calculated. Results: A considerable proportion of older adults had a range of physical symptoms, depressive mood state and memory problems. Mean number of health problems reported were 4.8±3.3 (male 4.4±3.1 and female 5.0±4.3). Cardiovascular risk was high, mean QRISK3 score for males were 22.2% (±14.4), and for females 10.3% (±6.6) (p<0.05). On average, the heart age was increased by 7.9±6.2 years (8.6±6.6 years for males and 5.0±3.3 for females). The relative risk of participants was 2.1 for males and 1.5 for females for heart attack or stroke within the ten years, compared to healthy persons. The symptoms and risk factors were elicited easily, and the process probably facilitated improving the awareness about the health concerns holistically. The survey also identified issues related to the engagement of older adults in the existing health care systems. Conclusions: The results suggested that questionnaire-based health screening in a community can identify a range of health concerns and identify multi-morbidity in general and cardiovascular risks in particular. This process may help to focus on the appropriate public health awareness and intervention programmes required in the community.


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