scholarly journals The Basic Study of the Mechanism of Propofol-Related Infusion Syndrome Using a Murine Skeletal Muscle Injury Model

2019 ◽  
Vol 9 (3) ◽  
Author(s):  
Yuryo Murakami ◽  
Ryusuke Ueki ◽  
Taihei Tachikawa ◽  
Munetaka Hirose
Keyword(s):  
Skeletal Muscle ◽  
Muscle Injury ◽  
Basic Study ◽  
Skeletal Muscle Injury ◽  
Injury Model ◽  
Murine Skeletal Muscle

505 Basic study for evaluation of skeletal muscle injury with electric impedance method

2008 ◽  
Vol 2007.20 (0) ◽  
pp. 173-174
Author(s):  
Hideo KONDO ◽  
Takayuki KITA ◽  
Kenichi YAMASAKI ◽  
Dohiko TERADA ◽  
Shigehiro HASHIMOTO ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Injury ◽  
Impedance Method ◽  
Electric Impedance ◽  
Basic Study ◽  
Skeletal Muscle Injury

scholarly journals Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model

2009 ◽  
Vol 14 (10) ◽  
pp. 2495-2505 ◽  
Author(s):  
Tomoyuki Nakasa ◽  
Masakazu Ishikawa ◽  
Ming Shi ◽  
Hayatoshi Shibuya ◽  
Nobuo Adachi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Regeneration ◽  
Muscle Injury ◽  
Local Injection ◽  
Rat Skeletal Muscle ◽  
Skeletal Muscle Injury ◽  
Injury Model

scholarly journals Stem Cells for the Treatment of Skeletal Muscle Injury

2009 ◽  
Vol 28 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Andres J. Quintero ◽  
Vonda J. Wright ◽  
Freddie H. Fu ◽  
Johnny Huard
Keyword(s):  
Skeletal Muscle ◽  
Stem Cells ◽  
Muscle Injury ◽  
Skeletal Muscle Injury

scholarly journals Modelling the skeletal muscle injury recovery using in vivo contrast-enhanced micro-CT: a proof-of-concept study in a rat model

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Bruno Paun ◽  
Daniel García Leon ◽  
Alex Claveria Cabello ◽  
Roso Mares Pages ◽  
Elena de la Calle Vargas ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Rat Model ◽  
Muscle Injury ◽  
Micro Ct ◽  
Skeletal Muscle Injury ◽  
Monitoring Time ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Injury Recovery

Abstract Background Skeletal muscle injury characterisation during healing supports trauma prognosis. Given the potential interest of computed tomography (CT) in muscle diseases and lack of in vivo CT methodology to image skeletal muscle wound healing, we tracked skeletal muscle injury recovery using in vivo micro-CT in a rat model to obtain a predictive model. Methods Skeletal muscle injury was performed in 23 rats. Twenty animals were sorted into five groups to image lesion recovery at 2, 4, 7, 10, or 14 days after injury using contrast-enhanced micro-CT. Injury volumes were quantified using a semiautomatic image processing, and these values were used to build a prediction model. The remaining 3 rats were imaged at all monitoring time points as validation. Predictions were compared with Bland-Altman analysis. Results Optimal contrast agent dose was found to be 20 mL/kg injected at 400 μL/min. Injury volumes showed a decreasing tendency from day 0 (32.3 ± 12.0mm3, mean ± standard deviation) to day 2, 4, 7, 10, and 14 after injury (19.6 ± 12.6, 11.0 ± 6.7, 8.2 ± 7.7, 5.7 ± 3.9, and 4.5 ± 4.8 mm3, respectively). Groups with single monitoring time point did not yield significant differences with the validation group lesions. Further exponential model training with single follow-up data (R2 = 0.968) to predict injury recovery in the validation cohort gave a predictions root mean squared error of 6.8 ± 5.4 mm3. Further prediction analysis yielded a bias of 2.327. Conclusion Contrast-enhanced CT allowed in vivo tracking of skeletal muscle injury recovery in rat.

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