Cytopathological findings of primary Merkel cell carcinoma of the lymph node metastases arising from the tongue with spontaneous regression

2021 ◽  
Vol 60 (6) ◽  
pp. 337-343
Author(s):  
Tomoya MIYAKE ◽  
Yoshimi FUKUSHIMA ◽  
Yudai MATSUOKA ◽  
Takenobu WADA ◽  
Yutaka TSUTSUMI ◽  
...  
Keyword(s):  
Lymph Node ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Lymph Node Metastases ◽  
Spontaneous Regression ◽  
Merkel Cell ◽  
Node Metastases

scholarly journals Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0180426 ◽  
Author(s):  
Georg Haymerle ◽  
Stefan Janik ◽  
Alexandra Fochtmann ◽  
Johannes Pammer ◽  
Helga Schachner ◽  
...  
Keyword(s):  
Lymph Node ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Lymph Node Metastases ◽  
T Antigen ◽  
Merkel Cell ◽  
Large T Antigen ◽  
Poor Outcome ◽  
Node Metastases

scholarly journals Merkel Cell Carcinoma with Lymphoepithelioma-Like Pattern: A Case Report of an Exceedingly Rare Variant of Merkel Cell Carcinoma with Lymph Node Metastases at Presentation

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Soumaya Ben Abdelkrim ◽  
Abdelmajid Dhouibi ◽  
Adnène Moussa ◽  
Rim Hadhri ◽  
Leila Njim ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Lymph Node Metastases ◽  
Host Response ◽  
Good Prognosis ◽  
Merkel Cell ◽  
Lymphoid Stroma ◽  
Node Metastases

Merkel cell carcinoma (MCC) or primary neuroendocrine carcinoma of the skin is a rare neoplasm with aggressive behavior. Primary lymphoepithelioma-like (LEL) carcinoma of the skin is a recently described exceptional tumor, with a relatively good prognosis, and is characterized by a neoplastic epithelial component associated with a dense lymphoid stroma. Rarely, MCC shows a marked lymphocytic host response or can even mimic a LEL carcinoma. We report a new case of MCC mimicking an LEL carcinoma in a 72-year-old male; the diagnosis of MCC was made on the basis of the morphology and immunohistochemical findings. We present through this case an exceptional pattern of MCC which can be misleading, and we insist on differential diagnoses.

scholarly journals Immunotherapy with imiquimod and interferon alfa for metastasized Merkel cell carcinoma

2016 ◽  
Vol 23 (2) ◽  
pp. 150 ◽  
Author(s):  
R.U. Wahl ◽  
T. Braunschweig ◽  
A. Ghassemi ◽  
A. Rübben
Keyword(s):  
Lymph Node ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Lymph Node Metastases ◽  
Neuroendocrine Tumour ◽  
Regional Lymph Node ◽  
Pegylated Interferon ◽  
Interferon Alfa ◽  
Merkel Cell ◽  
Node Metastases

Merkel cell carcinoma (mcc) is a highly aggressive neuroendocrine tumour of the skin. Remission rates are high with chemotherapy in patients with metastasis, but without any improvement in overall survival.We present the case of a 90-year-old woman with facial mcc. After radiation and surgery, the mcc recurred with widespread cutaneous and regional lymph node metastases. The metastases were treated with weekly intralesional injections of 1–2×106 IU interferon alfa-2a, accompanied by topical imiquimod 5% cream 3 times weekly. After partial regression, subcutaneous pegylated interferon alfa-2b was added at a dose of 30 μg weekly, which was then increased to 50 μg weekly. At 4 months after the start of immunotherapy, all cutaneous metastases and the intralesionally treated lymph node metastases receded. Interruption or reduction of systemic interferon application resulted in locoregional relapses that were successfully treated with surgery or intralesional interferon injections. The patient remains alive 30 months after initiation of immunotherapy, suggesting that locally metastasized mcc might be able to be controlled with local and systemic immunotherapy.

Lymph Node Metastases of Merkel Cell Carcinoma from Unknown Primary Site: Report of Three Cases

2008 ◽  
Vol 94 (5) ◽  
pp. 758-761 ◽  
Author(s):  
Luigi De Cicco ◽  
Andrea Vavassori ◽  
Barbara A Jereczek-Fossa ◽  
Giancarlo Pruneri ◽  
Gianpiero Catalano ◽  
...  
Keyword(s):  
Lymph Node ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Lymph Node Metastases ◽  
Primary Site ◽  
Unknown Primary ◽  
Merkel Cell ◽  
Unknown Primary Site ◽  
Node Metastases

scholarly journals A Spontaneous Regression of an Isolated Lymph Node Metastasis from a Primary Unknown Merkel Cell Carcinoma in a Patient with an Idiopathic Hyper-Eosinophilic Syndrome

2018 ◽  
Vol 19 ◽  
pp. 1437-1440
Author(s):  
Raffaele Longo ◽  
Oana Balasanu ◽  
Mathilde Chastenet de Castaing ◽  
Eric Chatelain ◽  
Mohammed Yacoubi ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Spontaneous Regression ◽  
Merkel Cell ◽  
Node Metastasis
Sign in / Sign up

Export Citation Format

Share Document