Usefulness of liquid based cytology (LBC) in fine needle aspiration for breast lesions

2019 ◽  
Vol 58 (2) ◽  
pp. 75-81
Author(s):  
Hiromi KUBOTA ◽  
Chisato MOTOYOSHI ◽  
Shingo SAKAMOTO ◽  
Yoko MIYOSHI ◽  
Koji KADOYA ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Fine Needle ◽  
Liquid Based Cytology

The role of liquid-based cytology in the investigation of breast lesions using fine-needle aspiration: A cytohistopathological evaluation

2005 ◽  
Vol 89 (2) ◽  
pp. 75-78 ◽  
Author(s):  
Konstantinos Kontzoglou ◽  
Konstantinos G. Moulakakis ◽  
Petros Konofaos ◽  
Mary Kyriazi ◽  
Aspasia Kyroudes ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Fine Needle ◽  
Liquid Based Cytology

scholarly journals Clinical Significance of Fine Needle Aspiration in Managing Patients with Breast Lesions

Folia Medica ◽  
2018 ◽  
Vol 60 (3) ◽  
pp. 364-372
Author(s):  
Konstantinos Dinas ◽  
Georgios C. Pratilas ◽  
Maria Nasioutziki ◽  
Eleftherios Vavoulidis ◽  
Vasileios Makris ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Assessment System ◽  
Breast Lesions ◽  
Fine Needle ◽  
Triple Assessment ◽  
First Choice ◽  
Pathological Evaluation ◽  
Liquid Based Cytology ◽  
Needle Aspiration Cytology

Abstract Background: Fine needle aspiration cytology (FNAC) has been and still is challenged about its role in the management of breast lesions. Guidelines today mandate that breast lesions should be managed with a triple assessment system consisting of clinical, radiological, and pathological evaluation. Aim: This article will try and clarify whether FNAC stands as a tool in this assessment. Materials and methods: PubMed was searched for articles concerning prospective, retrospective and review studies about clinical applications of FNAC. Results: Specialists agree and evidence occurs that FNAC could be the examination of first choice in matters of pathological evaluation. Conclusions: It is an easily performed, patient-friendly and cheap examination. It can successfully and quite quickly filter out benign breast conditions without any further cost or stress to the patient. In cases with inconclusive results or insufficient samples it should be followed by needle core biopsy (NCB). As a method, it has its limitations. It cannot directly provide information about tissue architecture, and identify certain breast conditions. Modern developments in liquid based cytology (LBC) upgrade its role in neoadjuvant chemotherapy too. In order to have satisfactory results, high levels of experience are required.

Accuracy of Breast Fine-Needle Aspiration Biopsy Using the International Academy of Cytology Yokohama System in Clinico-Radiologically Indeterminate Lesions: Initial Findings Demonstrating Value in Lesions of Low Suspicion of Malignancy

2021 ◽  
pp. 1-7
Author(s):  
Shruti Agrawal ◽  
Michael Leonard Anthony ◽  
Pranoy Paul ◽  
Divya Singh ◽  
Akansha Agarwal ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Breast Lesions ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Biopsy ◽  
International Academy

<b><i>Background:</i></b> Fine-needle aspiration biopsy (FNAB) in breast lesions offers accurate results in differentiating benign and malignant lesions. However, its role is unclear when core-needle biopsy (CNB) is available, the latter providing additional information regarding tumor grade, invasion, and hormone receptor status in malignant lesions. In benign breast lesions, especially in BIRADS category 4a and 4b, FNAB, and CNB provide similar pathological information, whereby FNAB may serve as a more rapid and cost-effective investigation. The study was planned to reevaluate the diagnostic accuracy of FNAB in BIRADS category 4a, 4b, and 4c lesions. <b><i>Materials and Methods:</i></b> FNAB and biopsy reports of all patients with breast lesions sent between September 1, 2018, and November 30, 2020, were collected and the International Academy of Cytology (IAC) Yokohama category and BIRADS score were recorded for each case. The rate of malignancy and the accuracy of FNAB in diagnosing malignancy were calculated for each BIRADS 4a, 4b, and 4c subgroup. <b><i>Results:</i></b> A total of 249 cases of BIRADS 4 lesions had corresponding cytology and histopathology diagnoses. FNAB showed high diagnostic accuracy in all BIRADS groups. A benign categorization was associated with a very low number of false-negative diagnoses, especially in BIRADS 4a lesions. <b><i>Conclusion:</i></b> The study reconfirms the excellent accuracy of breast FNAB using the IAC Yokohama system in diagnosing breast malignancies. Furthermore, BIRADS 4a lesions found to be belonging to the cytological benign category may be excluded from CRB and kept on clinical follow-up.

Fine Needle Aspiration Biopsy of Breast Lesions and Histopathologic Correlation

1997 ◽  
Vol 41 (3) ◽  
pp. 705-712 ◽  
Author(s):  
Premila De Souza Rocha ◽  
Nisha Sunil Nadkarni ◽  
Suzette Menezes
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Breast Lesions ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

scholarly journals Fine-needle aspiration biopsy for breast lesions: a comparison between two devices for obtaining cytological samples

2005 ◽  
Vol 123 (6) ◽  
pp. 271-276 ◽  
Author(s):  
Ruffo Freitas Júnior ◽  
Marise Amaral Rebouças Moreira ◽  
Gustavo Antônio de Souza ◽  
Ellen Hardy ◽  
Regis Resende Paulinelli
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Breast Lesions ◽  
Fine Needle ◽  
Vacuum Device ◽  
Needle Aspiration Biopsy ◽  
Breast Lumps

CONTEXT AND OBJECTIVE: Fine-needle aspiration biopsy has been accepted worldwide for breast lesions. However, some questions remain, including the appropriateness of the puncture method. The objective of this work was to compare aspirates obtained by the auto-vacuum device and by the syringe pistol holder. DESIGN AND SETTING: Randomized trial for validation of diagnostic method, at Hospital das Clínicas da Universidade Federal de Goiás and Hospital Araújo Jorge, Goiânia. METHODS: 351 patients presenting breast lumps underwent fine-needle aspiration biopsy, either with the auto-vacuum device or the syringe pistol holder. A single cytopathologist analyzed all of the cytology slides. The rates of insufficient material, cellularity, cell distortion and background hemorrhage were evaluated. RESULTS: The percentages of insufficient material were 16% and 22% (p = 0.18), for the auto-vacuum and pistol aspirates, respectively. Good cellularity was seen in 34% of auto-vacuum and 29% of pistol samples (p = 0.4). Cell distortion was seen in 31 and 26 cases, respectively (p = 0.7). Background hemorrhage occurred in 63 (35%) and 54 cases (31%) (p = 0.2), for auto-vacuum and pistol. The sensitivity was 88% and 86%; specificity 99% and 100%, positive predictive value 96% and 100%, negative predictive value 96% and 95% and total accuracy 76% and 75% for the auto-vacuum and pistol, respectively. CONCLUSION: The results obtained from the two fine-needle aspiration biopsy methods were equivalent. Therefore, the auto-vacuum device is a good option for obtaining aspirates for cytology.

Fine Needle Aspiration of Poorly Defined Indurated and Well-Defined Breast Lesions

2007 ◽  
Vol 51 (5) ◽  
pp. 692-698
Author(s):  
Hidehiro Takei ◽  
Bernardo Ruiz ◽  
Jane Dancer ◽  
John Hicks
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Fine Needle

scholarly journals A Clinicopathologic Study of Various Breast Lesions by Fine Needle Aspiration Cytology (FNAC)

2018 ◽  
Vol 8 (3-4) ◽  
pp. 27-31
Author(s):  
Kazi Farzana Khanam ◽  
Nasima Akter ◽  
Tarana Tabashum ◽  
Abu Khalid Muhammad Maruf Raza ◽  
Asma Ul Hosna ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Clinicopathologic Study ◽  
Needle Aspiration Cytology
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