scholarly journals A case report of unique breast carcinoma in elderly female. Solid papillary carcinoma with signet ring cells and neuroendocrine differentiation.

1998 ◽  
Vol 37 (2) ◽  
pp. 181-185
Author(s):  
Yukari NAITO ◽  
Emiko NAKAMURA ◽  
Kyoichi MIYAGAWA ◽  
Toshio SHIMIZU ◽  
Kenji KAWAGUCHI ◽  
...  
Keyword(s):  
Case Report ◽  
Breast Carcinoma ◽  
Papillary Carcinoma ◽  
Neuroendocrine Differentiation ◽  
Signet Ring Cells ◽  
Elderly Female ◽  
Solid Papillary Carcinoma ◽  
Signet Ring

scholarly journals Invasive solid papillary carcinoma with neuroendocrine differentiation of the breast: a case report and literature review

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Xue Lin ◽  
Yoshiaki Matsumoto ◽  
Tomomi Nakakimura ◽  
Kazuo Ono ◽  
Shigeaki Umeoka ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Papillary Carcinoma ◽  
Neuroendocrine Differentiation ◽  
Solid Papillary Carcinoma

Vulvar Encapsulated Solid Papillary Carcinoma With Neuroendocrine Differentiation: A Case Report

2011 ◽  
Vol 20 (1) ◽  
pp. 97-100
Author(s):  
Cunxian Zhang ◽  
M. Ruhul Quddus ◽  
C. James Sung ◽  
Richard G. Moore ◽  
W. Dwayne Lawrence
Keyword(s):  
Case Report ◽  
Papillary Carcinoma ◽  
Neuroendocrine Differentiation ◽  
Solid Papillary Carcinoma

Synchronous Bilateral Solid Papillary Carcinoma of Breast: A Rare Case Report

2020 ◽  
pp. 1-3
Author(s):  
Ayşe Nur Uğur Kılınç ◽  
Ayşe Nur Uğur Kılınç ◽  
Zeynep Bayramoğlu ◽  
Yaşar Ünlü ◽  
Nergis Aksoy ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Papillary Carcinoma ◽  
Rare Case ◽  
Neuroendocrine Differentiation ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
Breast Cancers ◽  
Rare Type ◽  
Solid Papillary Carcinoma

Background: Solid papillary carcinoma is a rare type of carcinoma that accounts for less than 1% of all breast cancers and mostly seen in postmenopausal women. This report presents a rare case of synchronous bilateral solid papillary carcinoma of the breast. Case Report: A 74-year-old female patient had a mass in her right and left breast. Bilateral total mastectomy and sentinel lymph node biopsy were performed. The pathologic diagnosis was synchronous bilateral solid papillary carcinoma. No lymph node metastasis was detected in either of the breasts. Conclusion: To our knowledge, little is known about simultaneous bilateral solid papillary carcinomas. Solid papillary carcinoma should be kept in mind in the differential diagnosis of bilateral breast masses with neuroendocrine differentiation in elderly patients.

Cytology Detects Endobronchial Metastasis from Appendiceal Signet-Ring Cell Carcinoma in the Absence of Radiographic Lung Masses: A Case Report

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S44-S44
Author(s):  
B W Taylor ◽  
K Hummel ◽  
Y Xu
Keyword(s):  
Case Report ◽  
Respiratory Distress ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Signet Ring Cells ◽  
Endobronchial Metastasis ◽  
Signet Ring ◽  
Ring Cell ◽  
The Right

Abstract Introduction/Objective Endobronchial metastasis (EBM) is uncommon, with a reported prevalence of 2% in cases of non-lung primary malignancies. The most frequently observed carcinomas in EBM are from breast, colon, and renal origins. We present a rare case of endobronchial metastasis from a primary tumor of the appendix without lung masses by computed tomography (CT). Methods/Case Report An 83-year-old woman with signet-ring cell carcinoma of the appendix underwent right hemicolectomy and chemotherapy. Two years later, she returned with intractable nausea and vomiting, and respiratory distress. CT of the chest demonstrated diffuse bilateral pulmonary opacities without lung masses. CT of the abdomen showed peritoneal carcinomatosis. Cytology of ascitic fluid displayed metastasis of the patient’s known appendiceal tumor. Bronchoscopy found significant friable debris appearing to be tumor tissue and occluding multiple bronchioles in the right lung. A bronchoalveolar lavage (BAL) specimen from the right lung was sent for liquid-based cytology, which revealed a few atypical cells with eccentric nuclei and intracytoplasmic vacuoles, abundant macrophages, degenerated mixed inflammatory cells, and scattered bronchial epithelial cells. Cell block demonstrated signet-ring cells mimicking macrophages and infiltrating into small fragments of bronchiolar wall. The signet-ring cells were morphologically similar to those found in the ascitic fluid and the patient’s primary tumor, and were highlighted by mucicarmine stain and immunohistochemical stains for CDX-2 and CK20, but not CK7. Results (if a Case Study enter NA) N/A Conclusion Collectively, the findings supported the diagnosis of endobronchial metastasis of signet-ring cell carcinoma from the lower gastrointestinal tract, i.e. the patient’s known appendiceal primary. Our case demonstrates a rare endobronchial metastasis of a primary neoplasm of the appendix, an important diagnostic consideration when evaluating respiratory distress in patients with such cancer histories. We have described the significant role of BAL cytology to uncover endobronchial metastases without lung masses by CT, and illustrated the finding of signet-ring cells mimicking macrophages in a BAL cytology specimen.

scholarly journals Neuroendocrine Differentiation in Breast Cancer: Clinicopathological Significance of Bcl-2 Positive Solid Papillary Carcinoma

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Yoichiro Okubo ◽  
Takuji Okubo ◽  
Yoshimi Okubo ◽  
Takao Ishiwatari
Keyword(s):  
Breast Cancer ◽  
Papillary Carcinoma ◽  
Neuroendocrine Tumors ◽  
Ductal Carcinoma ◽  
Neuroendocrine Differentiation ◽  
Prognostic Indicator ◽  
Low Grade ◽  
Term Survival ◽  
Solid Papillary Carcinoma ◽  
Poor Prognostic Indicator

Solid papillary carcinoma (SPC) is considered a rare malignant breast tumor. Maluf and Koerner first reported this disease entity as a special type of ductal carcinoma in situ with several characteristic histopathological features, including low-grade cellular atypia, intracellular or extracellular mucin deposition, and solid papillary growth pattern, as well as neuroendocrine differentiation. The present paper describes a case of SPC with bcl-2 expression, which is known as a marker for malignancy of neuroendocrine tumors. Interestingly, despite bcl-2 expression being a poor prognostic indicator of neuroendocrine tumors, the patient with this tumor has achieved long-term survival (approximately 6 years) at the time of writing this report. Because previous investigators reported that bcl-2 expression might play a role in the inhibition of the development of breast cancer, we suggest that bcl-2 expression might reflect a good prognosis in patients with SPC, rather than being a poor prognostic indicator, as it is in several types of neuroendocrine tumor. However, to confirm this hypothesis, further investigation is required.

scholarly journals Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report

2007 ◽  
Vol 125 (5) ◽  
pp. 297-299 ◽  
Author(s):  
Marcelo Lorenzi Marques ◽  
Gabriel Salum D'Alessandro ◽  
Daher Cezar Chade ◽  
Valéria Pereira Lanzoni ◽  
Samuel Saiovici ◽  
...  
Keyword(s):  
Case Report ◽  
Mucinous Adenocarcinoma ◽  
Rare Case ◽  
Bladder Tumor ◽  
Colorectal Adenocarcinoma ◽  
Signet Ring Cell ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Ring Cell ◽  
Primary Bladder

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

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