scholarly journals Biosensors: Design, Development and Applications

2021 ◽  
Author(s):  
Phumlani Tetyana ◽  
Poslet Morgan Shumbula ◽  
Zikhona Njengele-Tetyana
Keyword(s):  
Critical Role ◽  
High Sensitivity ◽  
Recognition System ◽  
Historical Overview ◽  
Design Development ◽  
Biological Recognition ◽  
Biomedical Diagnosis ◽  
Working Principle ◽  
Analytical Tools

The ability to detect even the slightest physiological change in the human body with high sensitivity and accurately monitor processes that impact human nature and their surroundings has led to an immense improvement in the quality of life. Biosensors continue to play a critical role across a myriad of fields including biomedical diagnosis, monitoring of treatment and disease progression, drug discovery, food control and environmental monitoring. These novel analytical tools are small devices that use a biological recognition system to investigate or detect molecules. This chapter covers the design and development of biosensors, beginning with a brief historical overview. The working principle and important characteristics or attributes of biosensors will also be addressed. Furthermore, the basic types of biosensors and the general applications of these biosensors in various fields will be discussed.

Motivating the staff of Jazan University

2013 ◽  
Vol 10 (1) ◽  
pp. 1261-1267
Author(s):  
Ali Medabesh
Keyword(s):  
Human Capital ◽  
Quality Of Service ◽  
Economic System ◽  
Endogenous Growth ◽  
Employee Satisfaction ◽  
Development Process ◽  
Empirical Investigation ◽  
Critical Role ◽  
Financial Investment

The quality of public services and the yield of organizations are not limited to the financial investment and innovation solely. Human capital plays a critical role in the growth and excellence in institutions, but its contribution remains dependent on several factors. Its role is not limited on quantitative and qualitative accumulating, because it should be coherent and integrated in the development process. The theories of endogenous growth contributed to account for the disparity in levels of development between countries, by assuming that the extent of human capital response or inversely lack of responsiveness the economic system. This inaction is usually the prime cause of the deterioration of the quality of service and lack of satisfaction of the citizens, in addition of the lack of employee satisfaction about the circumstances of his work. Hence, arose the significance of several research about the mechanisms of reducing non-enthusiasm for the job or complacency professional and indifference. Staff of Jazan University has been chosen as a context of the empirical investigation of this study. The data has been collected using a well designed questionnaire and analyzed by SPSS program.

Desain Media Pembelajaran Geometri SMP Menggunakan 3D Pageflip Professional Berbasis RME Terintegrasi STEM

2020 ◽  
Vol 8 (01) ◽  
pp. 55-66
Author(s):  
Feri Tiona Pasaribu ◽  
Yelli Ramalisa
Keyword(s):  
High Schools ◽  
Junior High ◽  
Junior High Schools ◽  
Design Development ◽  
Student Questionnaire ◽  
Implementation Stages ◽  
The Media ◽  
And Mathematics ◽  
Geometry Learning

The focus of this research is to design geometry learning mediain junior high schools based on RME and integrated with Science, Technology, Engineering and Mathematics (STEM) using 3D Pageflip Proffesional,and to explain quality of the learning media. In the process of design and development of this media used is the ADDIE development model which begins with the stages analysis, design, development, and  carried out an evaluation in each stages. Implementation stages will be continued in the following years research. This research resulted in a product in the form of geometry learning media in junior high schools especially eight grade according to purpose. Based on the validity test and practicality test the results obtained from the validation by material experts and media design experts were 4.09 namely 81.8% and 4.21 or 84.2%.Based on the criteria for the validity of the instrument, the criteria for "very valid" were obtained. And the practicality results, namely the results of teacher response questionnaire obtained an average of 4.26 or 85.19%, and the results of student questionnaire responses were 4.07 or 81.4%. Then based on the percentage criteria of practicality of the instrument, it is found that the criteria are very practical and the media can be implemented with minor revisions.

ASSECSSING MOCA TEST IN SUBACUTE STROKE PATIENTS AND COMPARE MOCA VERSUS MMSE

2016 ◽  
pp. 120-127
Author(s):  
Dinh Toan Nguyen
Keyword(s):  
Human Life ◽  
Statistical Significance ◽  
High Sensitivity ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Female Age ◽  
Subacute Stroke ◽  
Duration Of Illness ◽  
Dsm Iv

Background: Dementia after stroke, particularly subacute period is often overlooked. Today the quality of human life is increasingly high, finding scales that have high value for detection of dementia in patients with stroke is increasingly interested. MoCA test is high sensitivity with mild dementia and identify more abnormalities of awareness caused by vascular, but MoCA have not been studied much in Vietnam. Objective: Assessing MoCA test in subacute stroke patients and compare MoCA versus MMSE in these patients. Subjects: 90 patients with subacute stroke period, these people are being treated at Department of cardiovascular internal medicine at Hue Central Hospital, from 7/2014 - 7/2015. Methods: cross-sectional description and analysis. Results: The mean age is 65.57 ± 13.38, accounting for 54.4% male and 45.6% female. Age, duration of illness has weak correlation with MoCA. The risk factors: hypertension, stroke ischemic transient, alcoholism, smoking, heart disease, diabetes, dyslipidemia related no statistical significance with MoCA. The proportion of dementia in subacute stroke according MoCA is 82.2%. The concordance between MoCA and MMSE was good (kappa = 0.684). Using DSM-IV criteria as the gold standard we found MoCA more valuable in the dementia diagnosis than MMSE (AUC 0.864 versus 0.774, p <0.05). Conclusion: The rate of dementia in stroke subacute period according MoCA is quite high. MoCA is valuable than MMSE in detecting dementia in patients with stroke subacute period, this scale is short, easy to implement so should put into using widely in clinical practice. Key words: MoCA test, subacute stroke, dementia

scholarly journals The Effect of Informing Participants of the Response Bias of an Automated Target Recognition System on Trust and Reliance Behavior

2021 ◽  
pp. 001872082110217
Author(s):  
Shala Knocton ◽  
Aren Hunter ◽  
Warren Connors ◽  
Lori Dithurbide ◽  
Heather F. Neyedli
Keyword(s):  
Response Bias ◽  
Target Recognition ◽  
Rate Sensitivity ◽  
High Sensitivity ◽  
Recognition System ◽  
Decision Criterion ◽  
Detection Task ◽  
Mine Detection ◽  
Rate Condition ◽  
Consistent Response

Objective To determine how changing and informing a user of the false alarm (FA) rate of an automated target recognition (ATR) system affects the user’s trust in and reliance on the system and their performance during an underwater mine detection task. Background ATR systems are designed to operate using a high sensitivity and a liberal decision criterion to reduce the risk of the ATR system missing a target. A high number of FAs in general may lead to a decrease in operator trust and reliance. Methods Participants viewed sonar images and were asked to identify mines in the images. They performed the task without ATR and with ATR at a lower and higher FA rate. The participants were split into two groups—one informed and one uninformed of the changed FA rate. Trust and/or confidence in detecting mines was measured after each block. Results When not informed of the FA rate, the FA rate had a significant effect on the participants’ response bias. Participants had greater trust in the system and a more consistent response bias when informed of the FA rate. Sensitivity and confidence were not influenced by disclosure of the FA rate but were significantly worse for the high FA rate condition compared with performance without the ATR. Conclusion and application Informing a user of the FA rate of automation may positively influence the level of trust in and reliance on the aid.

scholarly journals Gold–Carbon Nanocomposites for Environmental Contaminant Sensing

Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 719
Author(s):  
Shahrooz Rahmati ◽  
William Doherty ◽  
Arman Amani Babadi ◽  
Muhamad Syamim Akmal Che Mansor ◽  
Nurhidayatullaili Muhd Julkapli ◽  
...  
Keyword(s):  
Environmental Pollutants ◽  
High Sensitivity ◽  
Environmental Crisis ◽  
World Population ◽  
Chemical Contaminants ◽  
Carbon Nanocomposites ◽  
Minimal Sample ◽  
Wide Range ◽  
And Control ◽  
Analytical Tools

The environmental crisis, due to the rapid growth of the world population and globalisation, is a serious concern of this century. Nanoscience and nanotechnology play an important role in addressing a wide range of environmental issues with innovative and successful solutions. Identification and control of emerging chemical contaminants have received substantial interest in recent years. As a result, there is a need for reliable and rapid analytical tools capable of performing sample analysis with high sensitivity, broad selectivity, desired stability, and minimal sample handling for the detection, degradation, and removal of hazardous contaminants. In this review, various gold–carbon nanocomposites-based sensors/biosensors that have been developed thus far are explored. The electrochemical platforms, synthesis, diverse applications, and effective monitoring of environmental pollutants are investigated comparatively.

Efficient chemosensors for toxic pollutants based on photoluminescent Zn(II) and Cd(II) metal-organic networks

2021 ◽  
Author(s):  
Luis David Rosales-Vazquez ◽  
Alejandro Dorazco-González ◽  
Victor Sanchez-Mendieta
Keyword(s):  
Optical Sensors ◽  
Three Dimensional ◽  
High Sensitivity ◽  
Environmental Research ◽  
Toxic Pollutants ◽  
Sensitivity And Selectivity ◽  
Metal Organic ◽  
Analytical Tools ◽  
Organic Networks

Optical sensors with high sensitivity and selectivity, as important analytical tools for chemical and environmental research, can be accomplished by straightforward synthesis of luminescent one-, two- and three-dimensional Zn(II) and...

scholarly journals AB0050 A NOVEL METHOD FOR ISOLATION OF EXOSOMES FROM SYNOVIAL FLUID

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1057.2-1057
Author(s):  
Y. Liu ◽  
Y. Huang ◽  
Q. Huang ◽  
S. Sun ◽  
Z. Ji ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Western Blot ◽  
Biological Fluid ◽  
High Sensitivity ◽  
Protein Distribution ◽  
Sds Page ◽  
Close Relationship ◽  
Novel Method ◽  
Low Levels

Background:Exosomes in synovial fluid (SF) has a close relationship with the pathogenesis of rheumatiod arthritis. As a complex biological fluid, SF presents challenges for exosomes isolation using standard methods, such as ExoquickTM kit and ultracentrifugation.Objectives:The study aims to compared the quality of exosomes separated by ExoquickTM kit (TM), ExoquickTM kit+ExoquickTC kit (TM-TC), ultracentrifugation (UC) and TM-TC+UC(TM-TC-UC) from SF.Methods:Exosomes was separated by TM, TM-TC, UC and TM-TC-UC respectively. The size and concentrations of exosomes were detected by high sensitivity flow cytometry for nanoparticle analysis. Total protein and RNA were extracted from exosomes. SDS-PAGE was used to detect the protein distribution of exosomes. Western blot was used to examine the level of albumin and exosomes marker (TSG101 and CD81).Results:There was no statistic difference in the diameters of exosomes separated by the four methods. The concentrations of exosomes in TM, TM-TC, TM-TC-UC and UC were (5.65±0.93), (3.02±1.19), (1.67±0.25) and (4.61±0.73) *109Particles/mL. The protein concentrations of exosomes separated by the four methods were consistent with the concentrations of exosomes. SDS-PAGE showed that the protein distribution of exosomes separated by the four methods were different. Low levels of albumin were detected in TM-TC and TM-TC-UC, while high levels of albumin in TM and UC. Total RNA concentrations from exosomes in TM-TC was higher than other groups.Conclusion:TM-TC can be used to obtain higher quality exosomes from SF for the study of exosome-enriched components.References:[1]Helwa I, et al, A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents. PloS one, 2017. 12(1): p. e0170628-e0170628.Figure 1.A: SDS-PAGE showed the protein distribution of exosomes; B: the detection of albumin, TSG101 and CD81 by western blot.Disclosure of Interests:None declared

scholarly journals Relationship between Emotional Intelligence and Violence Exerted, Received, and Perceived in Teen Dating Relationships

2021 ◽  
Vol 18 (5) ◽  
pp. 2284
Author(s):  
Cordelia Estevez-Casellas ◽  
Mª Dolores Gómez-Medina ◽  
Esther Sitges
Keyword(s):  
Emotional Intelligence ◽  
Social Relationships ◽  
Violent Behavior ◽  
Critical Role ◽  
Dating Relationships ◽  
Significant Relation ◽  
Violent Behaviors ◽  
Teen Dating ◽  
The Relationship

Emotional intelligence plays a critical role in adolescence since it involves a change towards psychological, social, and sexual maturity; a stage in which the foundations of intimate social relationships are established. Emotional competences regulate the quality of these relationships in adolescence and can provide protection against or facilitate the use of violence within them. Based on the above, this study aims to analyze the relationship between emotional intelligence and violence exercised, received, and perceived by adolescents in dating relationships. A sample of 254 subjects (43.1% men and 56.9% women) between 12 and 18 years old was analyzed through the Emotional Intelligence Questionnaires of BarOn ICE:NA and Violence Exercised Perceived and Received by Adolescents VERA. The results of the research have shown that there is a significant and inverse relation between the dimensions of emotional intelligence and the violence exercised by adolescents in their dating relationships, and a positive and significant relation between emotional intelligence and the perception of violent behavior. For this reason, the importance of educating people about emotional intelligence from childhood within both the academic and family sphere is highlighted. This is fundamental to preventing the appearance of such violent behaviors and promoting an adequate adaptation to the environment.

scholarly journals Association between Mutuality and Health-Related Quality of Life in Patient–Caregiver Dyads Living with Schizophrenia

2021 ◽  
Vol 18 (5) ◽  
pp. 2438
Author(s):  
Chiu-Yueh Hsiao ◽  
Huei-Lan Lu ◽  
Yun-Fang Tsai
Keyword(s):  
Quality Of Life ◽  
Critical Role ◽  
Health Related Quality ◽  
Dyadic Relationship ◽  
Cross Sectional ◽  
Actor Partner Interdependence Model ◽  
Related Quality ◽  
Health Related ◽  
Partner Effect

Background: Although caregivers are a crucial support in the recovery of patients with schizophrenia, little is known about how mutuality is related to health-related quality of life within the dyadic (patient and caregiver) context. This study aimed to investigate the dyadic relationship between mutuality and health-related quality of life in patients with schizophrenia and caregivers. Methods: A cross-sectional, correlational study was conducted with a sample of 133 dyads of patients with schizophrenia and caregivers. Structured questionnaires were used to collect data. Data were analyzed using descriptive statistics, paired sample t-tests, Pearson’s product-moment correlations, and the Actor–Partner Interdependence Model. Results: Mutuality of patients was significantly higher than that of caregivers. Compared with caregivers, patients had significantly lower total scores for health-related quality of life. Patients’ and caregivers’ mutuality was related to their own health-related quality of life (actor effect) and their partners’ health-related quality of life (partner effect). Conclusion: Mutuality plays a critical role in health-related quality of life in dyads of patients with schizophrenia and caregivers. Viewing a dyad as a unit of nursing care reveals a promising approach for developing recovery-oriented modalities targeted at stimulating mutuality that may enhance health-related quality of life for both patients and caregivers.

Materials Science and Engineering Education

MRS Bulletin ◽  
1992 ◽  
Vol 17 (9) ◽  
pp. 18-21 ◽  
Author(s):  
R. Abbaschian
Keyword(s):  
Quality Of Life ◽  
Iron Age ◽  
Materials Science ◽  
Critical Role ◽  
Economic Security ◽  
Intraocular Lenses ◽  
Science And Engineering ◽  
Materials Science And Engineering ◽  
Do So

Materials science and engineering (MSE), as a field as well as a discipline, has expanded greatly in recent years and will continue to do so, most likely at an even faster pace. It is now well-accepted that materials are crucial to the national defense, to the quality of life, and to the economic security and competitiveness of the nation. Mankind has recognized the importance of manmade materials to the quality of life for many centuries. In many cases, the security and defense of tribes and nations have substantially depended on the availability of materials. It is not surprising that historical periods have been named after materials—the Bronze Age, the Iron Age, etc. The major requirements from materials in those days were their properties and performance. Today, in this age of advanced materials, the importance of materials to defense and quality of life has not changed. However, the critical role of materials has taken an additional dimension: it has become essential to enhancing industrial competitiveness.The knowledge base within MSE has also expanded vastly throughout these years and continues to do so at an increasing rate. We are constantly gaining a deeper understanding of the fundamental nature of materials, developing new ways to produce and shape them for applications extending from automobiles to supersonic airplanes, optoelectronic devices to supercomputers, hip implants to intraocular lenses, or from household appliances to gigantic structures. We are also learning that, in many of these applications, we need to depend on the combinations or composites of different classes of materials (metals, ceramic, polymers, and electronic materials) to enhance their properties.

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