scholarly journals Anaphylactic Reactions in Radiology Procedures

2021 ◽  
Author(s):  
Callen Kwamboka Onyambu ◽  
Angeline Anyona Aywak ◽  
Sarah Kemunto Osiemo ◽  
Timothy Musila Mutala
Keyword(s):  
Radiology Department ◽  
Metered Dose Inhalers ◽  
Good Patient ◽  
Prompt Treatment ◽  
Good Patient Outcome ◽  
Iodinated Contrast ◽  
Metered Dose ◽  
Response Team ◽  
Life Threatening ◽  
Beta 2

Reactions to contrast agents are uncommon but range from mild urticaria to life threatening anaphylactic reactions. Majority of these reactions occur due to intravenous administration of iodinated contrast media. Acute reactions to MRI gadolinium-based contrast are much less common but they do occur and thus have to be managed. Usual presentations include urticaria, nausea, vomiting, angioedema, bronchospasm, laryngospasm and systemic hypotension. Majority of these reactions occur within the first twenty minutes after administration of contrast. Therefore, their recognition and prompt treatment are critical for good patient outcome. Attendant to this the radiology department must be adequately prepared to handle these emergencies as and when they do occur. This means an up to date emergency tray must be checked regularly before the start of the procedure, ensure there is epinephrine, antihistamines, beta-2-agonists metered dose inhalers, IV fluids, and ready supply of oxygen. Close collaboration of radiology staff with the hospital emergency response team is critical since severe reactions will need the intervention of this team.

Improved method to label beta-2 agonists in metered-dose inhalers with technetium-99m

1993 ◽  
Vol 24 (6) ◽  
pp. 787-794
Author(s):  
James R. Ballinger ◽  
Luanne E. Calcutt ◽  
Richard V. Hodder ◽  
Annette Proulx ◽  
Karen Y. Gulenchyn
Keyword(s):  
Improved Method ◽  
Metered Dose Inhalers ◽  
Technetium 99M ◽  
Metered Dose ◽  
Beta 2

Pharmacology Update: School Nurse Role and Emergency Medications for Treatment of Anaphylaxis

2021 ◽  
pp. 1942602X2110219
Author(s):  
Theresa A. Bingemann ◽  
Anil Nanda ◽  
Anne F. Russell
Keyword(s):  
Side Effects ◽  
School Personnel ◽  
Local Environment ◽  
School Nurses ◽  
First Line ◽  
Onset Of Action ◽  
Epinephrine Administration ◽  
Prompt Treatment ◽  
Nurse Role ◽  
Life Threatening

Anaphylaxis is a rapidly occurring allergic reaction that is potentially life threatening. Recognition of the early signs and prompt treatment of anaphylaxis is critical. School nurses are tasked with educating nonmedical school personnel on the recognition and treatment of anaphylaxis and emphasizing that epinephrine is the first line of treatment for anaphylaxis. Fortunately, there is now availability of multiple epinephrine administration devices. However, this also means that there are more devices that school nurses and nonmedical assistive personnel need to learn about to be able to administer in an emergency. Once epinephrine is administered, emergency medical services must be activated. Education regarding what to expect after the administration of epinephrine with respect to side effects and onset of action is also necessary. Though adjunctive medicines, such as antihistamines and inhalers, may also be administered after the injection of epinephrine, they should not be solely relied on in anaphylaxis. School nurses are uniquely situated for this role, as they understand the local environment in a school and can assess and reassess the needs of the faculty and staff.

Complete resection of a massive mesenteric lymphangioma in an adult

2020 ◽  
Vol 13 (3) ◽  
pp. e233714 ◽  
Author(s):  
Dominic Robert Parker ◽  
Philip Kiely ◽  
Richard Smith
Keyword(s):  
Patient Outcome ◽  
Preoperative Diagnosis ◽  
Lymphatic Vessels ◽  
Complete Resection ◽  
Surgical Team ◽  
Cystic Tumour ◽  
Good Patient ◽  
Mesenteric Lymphangioma ◽  
Good Patient Outcome ◽  
Massive Resection

Mesenteric lymphangioma is a benign cystic tumour of the lymphatic vessels that occurs rarely in adults. Due to the infrequency of cases and the insidious presentation, these tumours can be diagnosed late and become massive. Resection of mesenteric lymphangioma in its entirety is the recommended management in order to prevent recurrence. This case report describes the finding of a massive mesenteric lymphangioma (dimensions 420×470×100 mm) in a young man, the investigations leading to diagnosis, and the subsequent surgical management. The substantial size of this tumour produced considerable challenges for the surgical team, including involvement of adjacent small bowel and mesenteric vasculature. Preoperative diagnosis and assessment of the anatomy was pivotal in achieving a complete resection and a good patient outcome.

Metered-Dose Inhalers: Mouth Open or Closed?-Reply

JAMA ◽  
1994 ◽  
Vol 271 (4) ◽  
pp. 272
Author(s):  
Michael J. Tidd
Keyword(s):  
Metered Dose Inhalers ◽  
Metered Dose

scholarly journals Numerical and Experimental Investigation on Key Parameters of the Respimat® Spray Inhaler

Processes ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 44
Author(s):  
Yi Ge ◽  
Zhenbo Tong ◽  
Renjie Li ◽  
Fen Huang ◽  
Jiaqi Yu
Keyword(s):  
High Speed ◽  
Fine Particles ◽  
Geometric Parameters ◽  
Metered Dose Inhalers ◽  
Geometric Pattern ◽  
Long Duration ◽  
Metered Dose ◽  
New Type ◽  
Computational Fluid Dynamics Cfd ◽  
Spray Velocity

Respimat®Soft MistTM is a newly developed spray inhaler. Different from traditional nebulizers, metered-dose inhalers, and dry powder inhalers, this new type of inhaler can produce aerosols with long duration, relatively slow speed, and a high content of fine particles. Investigating the effect of the key geometric parameters of the device on the atomization is of great significance for generic product development and inhaler optimization. In this paper, a laser high-speed camera experimental platform is built, and important parameters such as the geometric pattern and particle size distribution of the Respimat®Soft MistTM are measured. Computational fluid dynamics (CFD) and the volume of fluid method coupled with the Shear Stress Transport (SST) k-ω turbulence model are applied to simulate the key geometric parameters of the device. The effects of geometric parameters on the spray velocity distribution and geometric pattern are obtained. The angle of flow collision, the sphere size of the central divider and the length and width of the flow channel show significant impacts on the spray atomization.

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