scholarly journals Genotype DQ2.5/DQ2.2 (ββ2/ββ2) and High Celiac Disease Risk Development

2019 ◽  
Author(s):  
Yanna Karla de Medeiros Nóbrega
Keyword(s):  
Celiac Disease ◽  
Disease Risk

Amerindian Mtdna Haplogroups And Celiac Disease Risk HLA Haplotypes In Mixed Blood Latin American Patients

2011 ◽  
pp. 1 ◽  
Author(s):  
Alejandra Parada ◽  
Magdalena Araya ◽  
Francisco Pérez-Bravo ◽  
Marco Méndez ◽  
Adriana Mimbacas ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Latin American ◽  
Disease Risk ◽  
Mtdna Haplogroups ◽  
Mixed Blood ◽  
Hla Haplotypes

Regional variation in celiac disease risk within Sweden revealed by the nationwide prospective incidence register

2008 ◽  
Vol 98 (2) ◽  
pp. 337-342 ◽  
Author(s):  
Cecilia Olsson ◽  
Hans Stenlund ◽  
Agneta Hörnell ◽  
Olle Hernell ◽  
Anneli Ivarsson
Keyword(s):  
Celiac Disease ◽  
Regional Variation ◽  
Disease Risk

Celiac disease risk stratification based on HLA-DQ heterodimer (HLA-DQA1 ~ DQB1) typing in a large cohort of adults with suspected celiac disease

2020 ◽  
Vol 81 (2-3) ◽  
pp. 59-64 ◽  
Author(s):  
Rok Seon Choung ◽  
John R. Mills ◽  
Melissa R. Snyder ◽  
Joseph A. Murray ◽  
Manish J. Gandhi
Keyword(s):  
Celiac Disease ◽  
Risk Stratification ◽  
Disease Risk ◽  
Large Cohort ◽  
Hla Dq ◽  
Hla Dqa1

scholarly journals Celiac Disease Risk Determined By HLA-DQ Genotype Protects Against Gvhd in a Dose-Responsive Manner

2020 ◽  
Vol 26 (3) ◽  
pp. S186
Author(s):  
Susan McClory ◽  
Viviane C. Cahen ◽  
Yimei Li ◽  
Jamie L. Duke ◽  
Dimitri S. Monos ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Disease Risk ◽  
Hla Dq

scholarly journals Replication of GWAS Coding SNPs Implicates MMEL1 as a Potential Susceptibility Locus among Saudi Arabian Celiac Disease Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Omar I. Saadah ◽  
Noor Ahmad Shaik ◽  
Babajan Banaganapalli ◽  
Mohammed A. Salama ◽  
Sameer E. Al-Harthi ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Cross Validation ◽  
Disease Risk ◽  
Saudi Arabian ◽  
Susceptibility Loci ◽  
Ethnic Populations ◽  
Allelic Distribution ◽  
Single Locus Analysis ◽  
Testing Accuracy ◽  
Saudi Patients

Celiac disease (CD), a gluten intolerance disorder, was implicated to have 57 genetic susceptibility loci for Europeans but not for culturally and geographically distinct ethnic populations like Saudi Arabian CD patients. Therefore, we genotyped Saudi CD patients and healthy controls for three polymorphisms, that is, Phe196Ser in IRAK1, Trp262Arg in SH2B3, and Met518Thr in MMEL1 genes. Single locus analysis identified that carriers of the 518 Thr/Thr (MMEL1) genotype conferred a 1.6-fold increased disease risk compared to the noncarriers (OR = 2.6; 95% CI: 1.22–5.54;P<0.01). This significance persisted even under allelic (OR = 1.55; 95% CI: 1.05–2.28;P=0.02) and additive (OR = 0.35; 95% CI: 0.17–0.71;P=0.03) genetic models. However, frequencies for Trp262Arg (SH2B3) and Phe196Ser (IRAK1) polymorphisms were not significantly different between patients and controls. The overall best MDR model included Met518Thr and Trp262Arg polymorphisms, with a maximal testing accuracy of 64.1% and a maximal cross-validation consistency of 10 out of 10 (P=0.0156). Allelic distribution of the 518 Thr/Thr polymorphism in MMEL1 primarily suggests its independent and synergistic contribution towards CD susceptibility among Saudi patients. Lack of significant association of IRAK and SH2B3 gene polymorphisms in Saudi patients but their association in European groups suggests the genetic heterogeneity of CD.

scholarly journals Meta-Analysis on Associations of RGS1 and IL12A Polymorphisms with Celiac Disease Risk

2016 ◽  
Vol 17 (4) ◽  
pp. 457 ◽  
Author(s):  
Cong-Cong Guo ◽  
Man Wang ◽  
Feng-Di Cao ◽  
Wei-Huang Huang ◽  
Di Xiao ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Disease Risk ◽  
Meta Analysis

scholarly journals Gluten in infants and celiac disease risk

2016 ◽  
Vol 10 (6) ◽  
pp. 669-670 ◽  
Author(s):  
Carin Andrén Aronsson ◽  
Kalle Kurppa ◽  
Daniel Agardh
Keyword(s):  
Celiac Disease ◽  
Disease Risk

Frequency of HLA celiac disease risk alleles and haplotypes in healthy adults in Tamil Nadu

2019 ◽  
Vol 38 (2) ◽  
pp. 178-182
Author(s):  
Venugopal Giriprasad ◽  
John Mechenro ◽  
Ramadass Balamurugan ◽  
Balakrishnan S. Ramakrishna
Keyword(s):  
Celiac Disease ◽  
Tamil Nadu ◽  
Disease Risk ◽  
Healthy Adults ◽  
Risk Alleles

Physician Review of a Celiac Disease Risk Estimation and Decision-Making Expert System

2019 ◽  
Vol 38 (8) ◽  
pp. 722-728
Author(s):  
Robert L. Pastore ◽  
Joseph A. Murray ◽  
Frederick D. Coffman ◽  
Antonina Mitrofanova ◽  
Shankar Srinivasan
Keyword(s):  
Decision Making ◽  
Celiac Disease ◽  
Expert System ◽  
Disease Risk ◽  
Risk Estimation ◽  
Physician Review

Sa1265 Cardiovascular Disease Risk Assessment of Adult Celiac Disease Patients in the Midwestern United States

2013 ◽  
Vol 144 (5) ◽  
pp. S-246 ◽  
Author(s):  
Adam C. Stein ◽  
Rahman Chaudhry ◽  
Shirley Paski ◽  
NurAlima Grandison ◽  
Tamar Polonsky ◽  
...  
Keyword(s):  
United States ◽  
Cardiovascular Disease ◽  
Risk Assessment ◽  
Celiac Disease ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Midwestern United States ◽  
Adult Celiac Disease
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