scholarly journals A Study of the Correlation between Bacterial Culture and Histological Examination in Children with Helicobacter pylori Gastritis

Histology ◽  
2019 ◽  
Author(s):  
Felicia Galoș ◽  
Gabriela Năstase ◽  
Cătălin Boboc ◽  
Cristina Coldea ◽  
Mălina Anghel ◽  
...  
1996 ◽  
Vol 192 (10) ◽  
pp. 1016-1021 ◽  
Author(s):  
G. Oberhuber ◽  
A. Püspök ◽  
C. Dejaco ◽  
J. Hammer ◽  
Ch. Zauner ◽  
...  

2013 ◽  
Vol 9 (4) ◽  
pp. e1003251 ◽  
Author(s):  
Ivana Hitkova ◽  
Gang Yuan ◽  
Florian Anderl ◽  
Markus Gerhard ◽  
Thomas Kirchner ◽  
...  

JGH Open ◽  
2021 ◽  
Vol 5 (10) ◽  
pp. 1197-1202
Author(s):  
Mariko Hojo ◽  
Akihito Nagahara ◽  
Takahiro Kudo ◽  
Tsutomu Takeda ◽  
Tamaki Ikuse ◽  
...  

1999 ◽  
Vol 123 (9) ◽  
pp. 778-781 ◽  
Author(s):  
Maher Toulaymat ◽  
Sharon Marconi ◽  
Jane Garb ◽  
Christopher Otis ◽  
Shirin Nash

Abstract Objectives.—To describe the endoscopic biopsy pathology of Helicobacter pylori gastritis, compare bacterial detection by immunohistochemistry using a specific antibody with the Genta stain, and to compare the relative costs of the 2 techniques. Design.—One hundred cases of gastritis identified as positive for H pylori by Genta stain and 100 cases considered negative by the same technique were stained using an anti-H pylori–specific polyclonal antibody. Laboratory reagent and labor costs for the 2 methods were compared. Results.—Chronic active gastritis with lymphoid follicles was significantly associated with H pylori infection (P < .0001). The immunohistochemical method had a sensitivity of 97% and a specificity of 98% compared with the Genta stain, with strong agreement for grading density of organisms (κ = 0.85; P < .001). Reagent costs were similar for both methods, but immunohistochemistry using an autoimmunostainer required less dedicated technical time and hence was less expensive than the Genta stain. Conclusions.—Immunohistochemistry using a specific antibody is an accurate and cost-effective method for H pylori detection in gastric biopsies.


2003 ◽  
Vol 121 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Jaime Natan Eisig ◽  
Fernando Marcuz Silva ◽  
Cláudio Hashimoto ◽  
Ethel Zimberg Chehter ◽  
Antonio Atilio Laudanna

CONTEXT: The curative treatment of peptic ulcer is made available nowadays through the eradication of the bacterium Helicobacter pylori, which is associated with it, but the best therapeutic regimen is yet to be determined. OBJECTIVE: To assess the efficacy of a therapeutic regimen with 400 mg ranitidine bismuth citrate associated with 500 mg clarithromycin given twice a day for seven days in a cohort of Brazilian patients with peptic ulcer. TYPE OF STUDY: Cross-sectional study. SETTING: Tertiary-care hospital. PATIENTS: One hundred and twenty nine outpatients, with active or healed peptic ulcers infected by Helicobacter pylori, diagnosed via endoscopy with confirmation via the urease test and histological examination, who had never undergone a regimen for the eradication of the bacterium. PROCEDURE: Administration of 400 mg ranitidine-bismuth and 500 mg clarithromycin twice a day, for seven days. MAIN MEASUREMENTS: Efficacy of the treatment, with a check on the cure done via another endoscopy eight weeks after drug administration. The eradication of the bacterium was determined via the urease test and histological examination. Patients who were negative for both were considered to be cured. RESULTS: Eight patients failed to complete the study. The eradication rate according to intention to treat was 81% (104/129) and per protocol was 86% (104/121). CONCLUSION: The bismuth ranitidine compound associated with clarithromycin used for one week was shown to be a simple, effective and well-tolerated therapeutic regimen for the eradication of Helicobacter pylori.


1996 ◽  
Vol 27 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Hala M.T El-Zimaity ◽  
David Y Graham ◽  
Mohammad T Al-Assi ◽  
Hoda Malaty ◽  
Tuomo J Karttunen ◽  
...  

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