scholarly journals Endoscopic findings of Helicobacter pylori gastritis in children and young adults based on the Kyoto classification of gastritis and age‐associated changes

JGH Open ◽  
2021 ◽  
Vol 5 (10) ◽  
pp. 1197-1202
Author(s):  
Mariko Hojo ◽  
Akihito Nagahara ◽  
Takahiro Kudo ◽  
Tsutomu Takeda ◽  
Tamaki Ikuse ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Young Adults ◽  
Endoscopic Findings ◽  
Children And Young Adults ◽  
Helicobacter Pylori Gastritis

scholarly journals Colonic Abnormalities in Manitoban Children with Helicobacter pylori Gastritis

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Upama Banik ◽  
Camelia Stefanovici ◽  
Jennifer Griffin ◽  
Wael El-Matary
Keyword(s):  
Weight Loss ◽  
Helicobacter Pylori ◽  
Retrospective Review ◽  
Medical Records ◽  
Significant Weight Loss ◽  
Endoscopic Findings ◽  
Bleeding Per Rectum ◽  
The Mean ◽  
H Pylori ◽  
Helicobacter Pylori Gastritis

Objectives. Association between Helicobacter pylori (H. pylori) and colonic pathology is underinvestigated. The aim of this work was to examine the prevalence and nature of colonic changes in children diagnosed with H. pylori gastritis. Methods. A comprehensive retrospective review of the medical records for all Manitoban children (≤17 years) diagnosed with H. pylori gastritis from January 1996 to May 2015 was conducted. Children with H. pylori gastritis who had colonoscopy were identified. Patients’ demographics, indications for colonoscopy, laboratory and endoscopic findings, and colonic histopathological abnormalities were documented. Results. A total of 231 children were found to have H. pylori gastritis. The mean age at diagnosis was 12.3 ± 4.1 years; 108 (46.6%) were girls. Of the 231 patients, 37 (16%) patients were found to have colonoscopy performed. Indications for colonoscopy included bleeding per rectum, significant weight loss, and hypoalbuminemia. Twenty-two (59%) of 37 children who had colonoscopy had significant endoscopic and histopathological findings on colonoscopy including polyposis and colitis. Boys with colonic changes were diagnosed at an earlier age compared to those without (11.5 ± 7.0 versus 15.0 ± 2.0, p<0.049). Conclusions. Our study may suggest a possible association between H. pylori and a subset of colonic changes in children.

scholarly journals Endoscopic severe mucosal atrophy indicates the presence of gastric cancer after Helicobacter pylori eradication

2020 ◽  
Author(s):  
Akiko Ohno ◽  
Jun Miyoshi ◽  
Atsushi Kato ◽  
Naohiko Miyamoto ◽  
Takahito Yatagai ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Intestinal Metaplasia ◽  
Eradication Therapy ◽  
Risk Scores ◽  
Forward Selection ◽  
Characteristic Analysis ◽  
Mucosal Atrophy ◽  
Endoscopic Findings

Abstract Background Gastric cancer after Helicobacter pylori (HP) eradication is a crucial clinical challenge today as HP eradication therapy is widely performed. Detecting gastric cancer after HP eradication tends to be difficult with normal white-light endoscopy. In the present study, we aimed to identify easily-evaluated endoscopic findings that indicate the presence of gastric cancer after HP eradication so that endoscopists can consider additional detailed examinations at the site. Methods We analyzed the endoscopic images of 43 patients who underwent endoscopic submucosal dissection for early gastric cancer after HP eradication and 119 patients with an HP eradication history who underwent esophagogastroduodenoscopy for a medical checkup. Endoscopic findings were evaluated according to the Kyoto classification of gastritis (atrophy, intestinal metaplasia, enlarged folds, nodularity, and diffuse redness) and map-like redness. Results Patients with gastric cancer had significantly higher total Kyoto risk scores; more atrophy, intestinal metaplasia, and diffuse redness; and a significantly higher prevalence of map-like redness compared with those without gastric cancer, in the univariate analyses. We used logistic regression analysis with forward selection based on the likelihood ratio to develop a model using atrophy and diffuse redness. Receiver operating characteristic analysis showed that a score of A2 in the Kyoto classification of gastritis (open-type atrophic pattern in the Kimura–Takemoto classification) was an endoscopic marker for the presence of post-HP-eradication gastric cancer. Conclusions Endoscopic severe gastric mucosal atrophy is useful to screen patients for gastric cancer after HP eradication.

Sign in / Sign up

Export Citation Format

Share Document