scholarly journals Interaction of Mitochondrial and Epigenetic Regulation in Hepatocellular Carcinoma

Liver Cancer ◽  
2018 ◽  
Author(s):  
Victoria Chagoya de Sánchez ◽  
Enrique Chávez ◽  
Gabriela Velasco- Loyden ◽  
María Guadalupe Lozano-Rosas ◽  
Alejandro Rusbel Aparicio-Cadena
Keyword(s):  
Hepatocellular Carcinoma ◽  
Epigenetic Regulation

scholarly journals Epigenetic Regulation in Hepatocellular Carcinoma Requires Long Noncoding RNAs

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Laura Amicone ◽  
Franca Citarella ◽  
Carla Cicchini
Keyword(s):  
Hepatocellular Carcinoma ◽  
Epigenetic Regulation ◽  
Tumor Suppressors ◽  
Biological Significance ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Therapeutic Approaches ◽  
Adult Liver ◽  
Liver Malignancy ◽  
Epigenetic Modifiers

Recent evidence has proven the relevance of epigenetic changes in the development of hepatocellular carcinoma (HCC), the major adult liver malignancy. Moreover, HCC onset and progression correlate with the deregulation of several long noncoding RNAs (lncRNAs), exhibiting great biological significance. As discussed in this review, many of these transcripts are able to specifically act as tumor suppressors or oncogenes by means of their role as molecular platforms. Indeed, these lncRNAs are able to bind and recruit epigenetic modifiers on specific genomic loci, ultimately resulting in regulation of the gene expression relevant in cancer development. The evidence presented in this review highlights that lncRNAs-mediated epigenetic regulation should be taken into account for potential targeted therapeutic approaches.

scholarly journals Epigenetic regulation of the Wnt signaling inhibitorDACT2in human hepatocellular carcinoma

Epigenetics ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. 373-382 ◽  
Author(s):  
Xiaomei Zhang ◽  
Yunsheng Yang ◽  
Xuefeng Liu ◽  
James G. Herman ◽  
Malcolm V. Brock ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Wnt Signaling ◽  
Epigenetic Regulation ◽  
Human Hepatocellular Carcinoma

scholarly journals Epigenetic regulation of OPA1 sensitizes hepatocellular carcinoma to sorafenib‐induced apoptosis (59.1)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
William Puszyk ◽  
Hui‐Jia Dong ◽  
Frank Zhao ◽  
Preston Shisgal ◽  
Roniel Cabrera ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Epigenetic Regulation ◽  
Induced Apoptosis

Epigenetic Regulation of Tumor Suppressor AKAP12 in Human Hepatocellular Carcinoma

2010 ◽  
Vol 48 (01) ◽  
Author(s):  
B Goeppert ◽  
P Schmezer ◽  
M Breinig ◽  
A Warth ◽  
MN Vogel ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Suppressor ◽  
Epigenetic Regulation ◽  
Human Hepatocellular Carcinoma
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