scholarly journals Aedes aegypti: The Main Enemy of Public Health in Brazil - Challenges and Perspective for Public Health

Malaria ◽  
2019 ◽  
Author(s):  
Erika M. de Carvalho ◽  
Simone S. Valverde ◽  
July A.H. Muñoz
Keyword(s):  
Public Health ◽  
Aedes Aegypti

Difusi dan Pola Spasial Sebaran Penyakit Demam Berdarah Dengue (DBD) Di Kota Bandar Lampung

2018 ◽  
Vol 1 (1) ◽  
pp. 87-95
Author(s):  
Nurul Qamila ◽  
Agel Vidian Krama
Keyword(s):  
Public Health ◽  
Spatial Analysis ◽  
Aedes Aegypti ◽  
Dengue Virus ◽  
Spatial Pattern ◽  
Dengue Hemorrhagic Fever ◽  
Health Problem ◽  
Public Health Problem ◽  
Hemorrhagic Fever ◽  
Descriptive Method

Dengue hemorrhagic fever (DHF) is a contagious disease caused by the dengue virus and is transmitted by the mosquito Aedes aegypti (Aa.aegypti). The population is still a public health problem that increases the number of sufferers and also widespread, with population and education. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the spatial pattern and the spread of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the descriptive method and spatial pattern of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. Keywords: DHF, Spatial Analysis

Detection of Flaviviral-Like DNA Sequences in Aedes aegypti (Diptera: Culicidae) Collected From Argentina

2021 ◽  
Author(s):  
Melisa B Bonica ◽  
Dario E Balcazar ◽  
Ailen Chuchuy ◽  
Jorge A Barneche ◽  
Carolina Torres ◽  
...  
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Dna Sequences ◽  
Immature Stages ◽  
Public Health Burden ◽  
The Past ◽  
Health Burden ◽  
The World ◽  
Aegypti Genome ◽  
Dengue Epidemics

Abstract Diseases caused by flaviviruses are a major public health burden across the world. In the past decades, South America has suffered dengue epidemics, the re-emergence of yellow fever and St. Louis encephalitis viruses, and the introduction of West Nile and Zika viruses. Many insect-specific flaviviruses (ISFs) that cannot replicate in vertebrate cells have recently been described. In this study, we analyzed field-collected mosquito samples from six different ecoregions of Argentina to detect flaviviruses. We did not find any RNA belonging to pathogenic flaviviruses or ISFs in adults or immature stages. However, flaviviral-like DNA similar to flavivirus NS5 region was detected in 83–100% of Aedes aegypti (L.). Despite being previously described as an ancient element in the Ae. aegypti genome, the flaviviral-like DNA sequence was not detected in all Ae. aegypti samples and sequences obtained did not form a monophyletic group, possibly reflecting the genetic diversity of mosquito populations in Argentina.

scholarly journals Chikungunya: epidemiology

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 82 ◽  
Author(s):  
Lyle R. Petersen ◽  
Ann M. Powers
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Aedes Albopictus ◽  
Chikungunya Virus ◽  
Mosquito Species ◽  
Febrile Illness ◽  
Current Understanding ◽  
Global Public Health ◽  
Temperate Climates

Chikungunya virus is a mosquito-borne alphavirus that causes fever and debilitating joint pains in humans. Joint pains may last months or years. It is vectored primarily by the tropical and sub-tropical mosquito, Aedes aegypti, but is also found to be transmitted by Aedes albopictus, a mosquito species that can also be found in more temperate climates. In recent years, the virus has risen from relative obscurity to become a global public health menace affecting millions of persons throughout the tropical and sub-tropical world and, as such, has also become a frequent cause of travel-associated febrile illness. In this review, we discuss our current understanding of the biological and sociological underpinnings of its emergence and its future global outlook.

scholarly journals The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Moritz UG Kraemer ◽  
Marianne E Sinka ◽  
Kirsten A Duda ◽  
Adrian QN Mylne ◽  
Freya M Shearer ◽  
...  
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Environmental Variables ◽  
Disease Burden ◽  
Health Planning ◽  
Global Distribution ◽  
Health Impacts ◽  
Global Public Health ◽  
Future Health ◽  
Autochthonous Transmission

Dengue and chikungunya are increasing global public health concerns due to their rapid geographical spread and increasing disease burden. Knowledge of the contemporary distribution of their shared vectors, Aedes aegypti and Aedes albopictus remains incomplete and is complicated by an ongoing range expansion fuelled by increased global trade and travel. Mapping the global distribution of these vectors and the geographical determinants of their ranges is essential for public health planning. Here we compile the largest contemporary database for both species and pair it with relevant environmental variables predicting their global distribution. We show Aedes distributions to be the widest ever recorded; now extensive in all continents, including North America and Europe. These maps will help define the spatial limits of current autochthonous transmission of dengue and chikungunya viruses. It is only with this kind of rigorous entomological baseline that we can hope to project future health impacts of these viruses.

scholarly journals LARVICIDAL ACTIVITY OF Caesalpinia ferrea MART. AND Lippia origanoides CHAM. AGAINST Aedes aegypti (LINNAEUS, 1762) (DIPTERA: CULICIDAE)

2020 ◽  
Vol 49 (1) ◽  
pp. 45-54
Author(s):  
Thiago Andre Santos de Andrade ◽  
Ivanise Maria de Santana ◽  
George Chaves Jimenez ◽  
Eulina Tereza Nery Farias ◽  
Lucia Oliveira de Macedo ◽  
...  
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Larvicidal Activity ◽  
Ethanol Extract ◽  
Chemical Compounds ◽  
Botanical Insecticide ◽  
Plant Metabolites ◽  
Important Public Health ◽  
Public Health Challenges ◽  
Ethanol Extracts

The control of Aedes aegypti has been considered one of the most important public health challenges worldwide. Chemical compounds have long been used for this purpose, but resistance to these molecules has also increased. Therefore, over the last few years several studies have focused on the development of alternative tools, particularly those based on plant metabolites. The purpose of this study was to assess the larvicidal activity of Caesalpinia ferrea and Lippia origanoides against Ae. aegypti. Larvae (L3) of Ae. aegypti Liverpool and Rockefeller strains, as well as of the Recife population were exposed to different concentrations  of C. ferrea (ranging from 13.1 to 105 mg/mL) and L. origanoides (ranging from 16.3 to 130 mg/mL), and the mortality rate was evaluated up to 48 hours after the beginning of the experiment. All tested groups and  ontrol group were quadruplicated. For C. ferrea, mortality ranged from 42.5% to 100% for Ae. aegypti Liverpool strain,from 67% to 100% for Ae. aegypti Rockfeller strain, and 57% to 100% for Ae. aegypti Recife population after 48 hours of larval exposure. For L. origanoides, the larvicidal activity ranged from 75% to 100% for Ae. aegypti Liverpool strain, from 61.5% to 100% for Ae. aegypti Rockfeller strain, and from 60.5% to 100% for Ae.aegypti Recife population. The hydro ethanol extract of C. ferrea and L. origanoides presented larvicidal activity against Ae. aegypti.KEY WORDS: Aedes aegypti; hydro ethanol extracts; Caesalpinia ferrea; Lippia sidoides; botanical insecticide; mosquitoes.

scholarly journals ANALISIS PELAKSANAAN PROGRAM PENGENDALIAN DEMAM BERDARAH DENGUE (DBD) DI PUSKESMAS KARYA WANITA KOTA PEKANBARU

2021 ◽  
Vol 1 (2) ◽  
pp. 443-456
Author(s):  
Qory Ayunitami ◽  
Herlina Susmaneli ◽  
Christine Vita Gloria Purba
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Health Center ◽  
Age Groups ◽  
Control Process ◽  
Control Program ◽  
Hemorrhagic Fever ◽  
Public Health Center ◽  
Dengue Disease ◽  
The Government

Demam Berdarah Dengue (DBD) merupakan salah satu jenis penyakit menular yang disebabkan oleh virus dengue yang ditularkan melalui gigitan nyamuk Aedes Aegypti. Penyakit DBD dapat muncul sepanjang tahun dan dapat menyerang seluruh kelompok umur. Puskesmas Karya Wanita merupakan daerah yang endemis yaitu daerah yang mudah terjangkit penyakit dalam jumlah besar salah satunya penyakit DBD. Upaya dari pemerintah untuk mengatasi penularan penyakit DBD dengan melakukan program pengendalian DBD. Program pengendalian ini berupa pemberantasan sarang nyamuk, penyelidikan epidemiologi dan penggulangan fokus. Kegiatan ini mempunyai tujuan utama diantaranya untuk menurunkan angka kesakitan, menurunkan angka kematian, dan mencegah terjadinya KLB penyakit DBD. Tujuan penelitian ini untuk menganalisis pelaksanaan program pengendalian DBD di Puskesmas Karya Wanita Kota Pekanbaru tahun 2020. Penelitian ini merupakan penelitian kualitatif deskriptif dengan pendekatan studi kasus. Subjek penelitian ini terdiri dari 1 informan kunci yaitu Kepala Puskesmas, 2 informan utama yaitu Pemegang Program DBD, Petugas Promosi Kesehatan, dan 2 informan pendukung yaitu Kader dan Masyarakat. Teknik yang digunakan dalam penelitian ini adalah wawancara mendalam dengan menggunakan bantuan pedoman wawancara serta analisis data dilakukan secara deskriptif dan disajikan dalam bentuk narasi . Hasil penelitian ini menunjukkan bahwa pelaksanaan program pengendalian DBD belum optimal, hal ini disebabkan oleh kurangnya dana untuk melaksanakan program ini, dan juga masih kurangnya partisipasi masyarakat dalam melakukan program Pemberantasan Sarang Nyamuk (PSN). Diharapkan kepada pihak puskesmas agar dapat bekerjasama dengan pihak terkait seperti Dinas Kesehatan Kota/Provinsi dan lintas sektor dalam pendanaan untuk semua kegiatan pengendalian DBD dan lebih memotivasi masyarakat agar ikut serta dalam proses pengendalian DBD. Dengue Hemorrhagic Fever (DHF) is a type of infectious disease caused by the dengue virus which is transmitted through the bite of the Aedes Aegypti mosquito. DHF can appear throughout the year and can affect all age groups. Karya Wanita Public Health Center is an endemic area, namely an area that is easily infected by large numbers of diseases, one of which is DHF. Efforts from the government to overcome the transmission of dengue disease by implementing a dengue control program. This control program takes the form of eradicating mosquito nests, epidemiological investigations and focus repetition. This activity has the main objective of reducing morbidity, reducing mortality, and preventing outbreaks of dengue fever. The purpose of this study was to analyze the implementation of the DHF control program at  Karya Wanita Public health center Pekanbaru City in 2020. This research is a descriptive qualitative research with a case study approach. The subjects of this study consisted of 1 key informant, namely the Head of the Puskesmas, 2 main informants, namely the DBD Program Holder, a Health Promotion Officer, and 2 supporting informants namely Cadres and the Community. The technique used in this research is in-depth interviews using interview guides and data analysis is done descriptively and presented in narrative form. The results of this study indicate that the implementation of the DHF control program is not optimal, this is due to the lack of funds to implement this program, and also the lack of community participation in carrying out the Mosquito Nest Eradication (PSN) program. It is hoped that the public health center will be able to collaborate with related parties such as the City / Provincial Health Office in funding for all DHF control activities and to further motivate the community to participate in the DHF control process

scholarly journals siRNA Design to Silence the 3′UTR Region of Zika Virus

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
María Perez-Mendez ◽  
Paola Zárate-Segura ◽  
Juan Salas-Benito ◽  
Fernando Bastida-González
Keyword(s):  
Public Health ◽  
Blood Transfusion ◽  
Aedes Aegypti ◽  
Cell Line ◽  
Birth Defects ◽  
Zika Virus ◽  
In Silico ◽  
Small Interfering Rnas ◽  
Medical Problems ◽  
Sirna Design

The disease caused by the Zika virus (ZIKV) has positioned itself as one of the main public health problems in Mexico. One of the main reasons is it causes microcephaly and other birth defects. The transmission of ZIKV is through Aedes aegypti and Ae. albopictus mosquitoes, which are found in a larger space of the national territory. In addition, it can also be transmitted via blood transfusion, sexual relations, and maternal-fetal route. So far, there are no vaccines or specific treatments to deal with this infection. Currently, some new therapeutics such as small interfering RNAs (siRNAs) are able to regulate or suppress transcription in viruses. Therefore, in this project, an in silico siRNA was designed for the 3′UTR region of ZIKV via bioinformatics tools. The designed siRNA was synthesized and transfected into the C6/36 cell line, previously infected with ZIKV in order to assess the ability of the siRNA to inhibit viral replication. The designed siRNA was able to inhibit significantly (p<0.05) ZIKV replication; this siRNA could be considered a potential therapeutic towards the disease that causes ZIKV and the medical problems generated.

scholarly journals Dengue NS1 antigen kit shows high sensitivity for detection of recombinant dengue virus-2 NS1 antigen spiked with Aedes aegypti mosquitoes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Philip Raj Abraham ◽  
Bharathy R ◽  
Pradeep Kumar N ◽  
Ashwani Kumar
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Dengue Virus ◽  
Infected Patient ◽  
Specific Treatment ◽  
High Sensitivity ◽  
Field Evaluation ◽  
Denv Infection ◽  
Ns1 Protein ◽  
Ns1 Antigen

AbstractDengue, caused by the dengue virus (DENV) is a significant vector-borne disease. In absence of a specific treatment and vaccine, dengue is becoming a rising threat to public health. Currently, control of dengue mainly focuses on the surveillance of the mosquito vectors. Improved surveillance methods for DENV in mosquito populations would be highly beneficial to the public health. However, current methods of DENV detection in mosquitoes requires specialized equipment and expensive reagents and highly trained personnel. As an alternative, commercially available dengue NS1 antigen ELISA kits could be used for detection of DENV infection in Aedes aegypti mosquitoes. In this study, we explored the utility of commercially available Dengue NS1 antigen kit (J. Mitra & Co. Pvt. Ltd) for the detection of recombinant dengue virus-2 (rDENV-2) NS1 protein and serum of dengue infected patient spiked with Ae. aegypti mosquito pools. The kit was found to be highly sensitive and specific towards detection of all serotypes of DENV. Further, it could detect as low as 750 femto gram rDENV-2 NS1 protein. It was also observed that rDENV-2 NS1 antigen spiked with blood-fed and unfed mosquito pools could be detected. In addition, the kit also detected dengue infected patient serum spiked with Ae. aegypti mosquito pools. Overall, the Dengue NS1 antigen kit displayed high sensitivity towards detection of recombinant as well as serum NS1 protein spiked with Ae. aegypti mosquito pools and could be considered for the dengue virus surveillance after a field evaluation in Ae. aegypti mosquitoes.

scholarly journals RELATIONSHIPS OF THE IMPLEMENTATION OF A 3M PLUS PROGRAM AND THE EXISTENCE OF AEDES AEGYPTI LARVAE TOWARDS THE NUMBER OF DENGUE FEVER CASES IN THE PUBLIC HEALTH CENTER OF TIGO BALEH BUKITTINGGI, WEST SUMATERA, INDONESIA

2017 ◽  
Vol 3 (3) ◽  
pp. 131-137
Author(s):  
Syukra Alhamda
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Health Center ◽  
Dengue Fever ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
Public Health Center ◽  
The Public ◽  
Index Value

Background: Dengue fever in Tigo baleh Bukittinggi community is one of the infectious diseases resulting in serious health problems. Understanding the factors associated with the disease is necessity.Objective: To determine the relationships of the implementation of 3M plus program and the existence of Aedes aegypti larvae towards the number of dengue fever cases in the public health center of Tigo Baleh Bukittinggi, West Sumatera, Indonesia.Methods: This was a case control study conducted between January and December 2016 in the Public Health Center of Tigo Baleh Bukittinggi. There were 78 samples recruited by total sampling, with 39 were assigned in the case and control group. House index (HI) and Container index (CI) were used to measure the presence of Aedes aegypti larvae. The implementation of 3M plus program was measured using questionnaire developed by the researcher. Chi Square was performed for data analysis. Result: Findings showed that house index value was 43.6% and container index was 17.9%. The presence of larvae at home contributes to 24 (61.5%) cases of DHF in the case group and 10 (25.6%) cases in the control group. Poor implementation of the program contributes to 27 (69.2%) cases in the case group and 17 (43.6%) in the control group. Chi square test showed p 0.040 (0.05) for the 3M plus implementation and p 0.03 (0.05) for the presence of Aedes aegypti. Conclusion: There were significant associations between the implementation of 3m plus program and the existence of Aedes aegypti larvae towards the number of dengue fever cases in the public health center of Tigo Baleh Bukittinggi, West Sumatera, Indonesia. It is suggested that the community should do more efforts to prevent the occurrence of DHF through mosquito nest eradication, such as the implementation of 3M Plus and sanitation efforts, and pay attention to any places that potentially become a breeding ground for Aedes aegypti mosquitoes.

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