scholarly journals Linking Only Aedes aegypti with Zika Virus Has World-Wide Public Health Implications

2017 ◽  
Vol 8 ◽  
Author(s):  
Fiona F. Hunter
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
World Wide ◽  
Health Implications

scholarly journals siRNA Design to Silence the 3′UTR Region of Zika Virus

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
María Perez-Mendez ◽  
Paola Zárate-Segura ◽  
Juan Salas-Benito ◽  
Fernando Bastida-González
Keyword(s):  
Public Health ◽  
Blood Transfusion ◽  
Aedes Aegypti ◽  
Cell Line ◽  
Birth Defects ◽  
Zika Virus ◽  
In Silico ◽  
Small Interfering Rnas ◽  
Medical Problems ◽  
Sirna Design

The disease caused by the Zika virus (ZIKV) has positioned itself as one of the main public health problems in Mexico. One of the main reasons is it causes microcephaly and other birth defects. The transmission of ZIKV is through Aedes aegypti and Ae. albopictus mosquitoes, which are found in a larger space of the national territory. In addition, it can also be transmitted via blood transfusion, sexual relations, and maternal-fetal route. So far, there are no vaccines or specific treatments to deal with this infection. Currently, some new therapeutics such as small interfering RNAs (siRNAs) are able to regulate or suppress transcription in viruses. Therefore, in this project, an in silico siRNA was designed for the 3′UTR region of ZIKV via bioinformatics tools. The designed siRNA was synthesized and transfected into the C6/36 cell line, previously infected with ZIKV in order to assess the ability of the siRNA to inhibit viral replication. The designed siRNA was able to inhibit significantly (p<0.05) ZIKV replication; this siRNA could be considered a potential therapeutic towards the disease that causes ZIKV and the medical problems generated.

Zika virus infections imported to Italy: Clinical, immunological and virological findings, and public health implications

2015 ◽  
Vol 63 ◽  
pp. 32-35 ◽  
Author(s):  
Lorenzo Zammarchi ◽  
Giulia Stella ◽  
Antonia Mantella ◽  
Dario Bartolozzi ◽  
Dennis Tappe ◽  
...  
Keyword(s):  
Public Health ◽  
Zika Virus ◽  
Virus Infections ◽  
Health Implications

scholarly journals Chemometric modeling of larvicidal activity of plant derived compounds against zika virus vectorAedes aegypti: application of ETA indices

RSC Advances ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. 4662-4670 ◽  
Author(s):  
Priyanka De ◽  
Rahul B. Aher ◽  
Kunal Roy
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Larvicidal Activity ◽  
Zika Virus ◽  
Qsar Model ◽  
Health Concerns

Dengue, zika and chikungunya have severe public health concerns in several countries. We have developed here a QSAR model for larvicidal activity of plant derived compounds against the vectorAedes aegypti.

scholarly journals GESTÃO DOS PNEUS INSERVÍVEIS E SUA CONTRIBUIÇÃO PARA O PROGRAMA DE PREVENÇÃO À DENGUE, FEBRE CHIKUGUNYA E ZIKA VÍRUS NO MUNICÍPIO DE CHAPECÓ (SC)

2018 ◽  
Vol 7 (1) ◽  
pp. 129-143
Author(s):  
Junir Antônio Lutinski ◽  
Suiane Oliveira De Quadros ◽  
Jessica Tiburski ◽  
Cleia De Fátima Bedim
Keyword(s):  
Public Health ◽  
Health Promotion ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Health Surveillance ◽  
Chikungunya Fever ◽  
Breeding Sites ◽  
Waste Tires ◽  
Urban Solid Waste ◽  
The Relationship

O potencial dos pneus inservíveis como criadouros para o mosquito Aedes aegypti, vetor da Dengue, febre Chikungunya e Zika vírus, é amplamente conhecido. Este estudo teve como objetivos descrever a gestão dos pneus inservíveis no município de Chapecó e avaliar relação entre o número de pneus destinados à Reciclanip e o número de focos de A. aegypti registrados em pneus. A coleta de dados foi realizada no período de maio a agosto de 2016 e teve como base o período de 2010 a 2015. Dados foram obtidos no sitio eletrônico da DIVE/SC e junto ao setor de Vigilância em Saúde Ambiental do município de Chapecó. A quantidade de pneus inservíveis recebidos pelo ecoponto triplicou no período avaliado. A correlação entre a gestão ambientalmente correta dos pneus inservíveis e o número de focos de A. aegypti foi negativa (r = -0,79) e significativa (p0,05). Os resultados encontrados permitem inferir que a gestão ambientalmente correta dos pneus inservíveis contribui positivamente para a promoção da saúde pública, na prevenção da Dengue, febre Chikungunya e Zika vírus.Palavras-chave: Gestão de resíduos. Logística reserva. Promoção da saúde. Resíduos sólidos urbanos. ABSTRACT: The potential of waste tires as breeding sites for the Aedes aegypti mosquito, Dengue, Chikungunya fever and Zika virus vector, is widely known. The aim of this study was to describe the management of waste tires in the municipality of Chapecó and to evaluate the relationship between the number of tires destined for Reciclanip and the number of A. aegypti outbreaks recorded in tires. Data collection was performed from May to August 2016 and was based on the period from 2010 to 2015. Data were obtained from the DIVE/SC website and from the Environmental Health Surveillance sector of Chapecó municipality. The amount of waste tires received by the ecopoint tripled in the evaluated period. The correlation between the environmentally correct management of the waste tires and the number of A. aegypti outbreaks was negative (r = -0.79) and significant (p 0.05). The results found allow to infer that the environmentally correct management of waste tires contributes positively to the promotion of public health in the prevention of Dengue, Chikungunya fever and Zika virus.Keywords: Waste management. Reserve logistics. Health promotion. Urban solid waste.

scholarly journals Zika virus in Brazil: an overview of public health policies

2020 ◽  
Vol 12 (10) ◽  
pp. e4597
Author(s):  
Heverton Valentim Colaço Da Silva ◽  
Almerinda Agrelli ◽  
Ana Sofia Lima Estevão De Oliveira ◽  
Ronald Rodrigues De Moura ◽  
Sergio Crovella ◽  
...  
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Clinical Symptoms ◽  
The State ◽  
Health Policies ◽  
Breeding Sites ◽  
Public Health Policies ◽  
Mosquito Breeding ◽  
Primary Focus

Objective: The purpose of this review was to discuss the effectiveness of public health policies in controlling Zika virus (ZIKV) in Brazil from 2015 to 2019 with an emphasis in the state of Pernambuco. Literature Review: Zika virus is an arbovirus primarily transmitted to humans by Aedes aegypti mosquitoes. Since 2015, the control of Aedes aegypti proliferation and diffusion has been a global subject of discussion due to its role in ZIKV transmission and the emergence of serious clinical symptoms resulting from this infection. In Brazil, the public policies established to control ZIKV outbreak were mostly based on vector control. Final Considerations: The coping model to manage the transmission vector of ZIKV is not showing to be effective.  Furthermore, until the social factors that favor the development and maintenance of mosquito breeding sites are eradicated, Brazil will continue to be susceptible to new outbreaks of mosquito-driven arboviruses. Here, we discussed the effectiveness of public health policies for the control of ZIKV in Brazil from 2015 to 2019, with a primary focus on the state of Pernambuco (PE).

scholarly journals Zika virus (ZIKV) disease: past, present and future

2018 ◽  
Vol 8 (6-s) ◽  
pp. 320-327 ◽  
Author(s):  
Sweety Khatri ◽  
Chandni Dhanoriya ◽  
Deepak Kumar Jain
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Mosquito Control ◽  
Rna Virus ◽  
Clinical Manifestations ◽  
Autoimmune Disorder ◽  
Public Health Authority ◽  
Health Crisis ◽  
The World

The mosquito-borne arbovirus Zika virus (positive-stranded RNA virus, ZIKV, Flavivirus, Flaviviridae), has caused an outbreak imposing by its extent and quick spread. This became the focus of a current pandemic and public health crisis all around the world because of the incessant geographic growth of both the virus and its mosquito vectors; it is often misdiagnosed with other disease like yellow fever, west nile, dengue and chikungunya because of same clinical manifestation. After unprecedented huge scale outbreak of ZIKV in Pacific, Micronesian island of Yap in 2007, though ZIKV infections are in general sporadic cases or causing mild self-limiting illness, harsh symptoms have been explained including neurological disorders, autoimmune disorder, fetal anomalies, impaired central nervous system of the fetus, microcephaly in newborns, meningoencephalitis, myelitis and Guillain Barre´Syndrome supposed to be linked with ZIKV. The virus is transmitted mainly by a mosquito Aedes aegypti, whereas, other routes of viral broadcast includes monkey bite, coitus and body fluids such as semen, blood and saliva which needs further corroboration. The relationship between these conditions with ZIKV infection is still not established and is under assessment. Till now there is no vaccine or specific antiviral against ZIKV, therefore the public health authority focuses on preventing infection, mainly in pregnant women and virus transmitted area. WHO and other health officials are working on the expansion of new projects and mosquito control techniques to manage up with infection as there is very fewer literature present on the pathogenesis of the ZIKV to help understand the clinical disease spectrum and target treatments to decrease or stop infection. The future status of ZIKV dispersal to other parts of the world is still unknown. The present review emphasizes various features of ZIKV and its history, epidemiology, transmission, clinical manifestations, progress  and advances in developing effective diagnostics, vaccines and drugs/therapeutics along with accepting suitable avoidance and control strategies to undertake this deadly emerging disease. Keywords: Zika virus, Flavivirus, Aedes aegypti, Pregnancy, Transmission, Microcephaly, Africa

Brazil's Zika fight will focus on mosquito eradication

2016 ◽  
Keyword(s):  
Public Health ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Public Health Emergency ◽  
Health Minister ◽  
Research Cooperation ◽  
Content Type ◽  
International Public Health ◽  
Recent Statement ◽  
Sanitation Infrastructure

Significance Health Minister Marcelo Castro's recent statement that Brazil is "badly losing the battle against the mosquito", though widely criticised, has proved to be politically significant. Questions have been raised as to how Brazil is currently combating the Aedes aegypti mosquito and the spread of the Zika virus. Impacts Shortcomings in health and sanitation infrastructure in poor regions may mar anti-Zika efforts. The outbreak will renew debate in other areas, such as legalisation of abortion. The declaration of Zika as an international public health emergency may boost global research cooperation.

scholarly journals Spondweni virus causes fetal harm in a mouse model of vertical transmission and is transmitted by Aedes aegypti mosquitoes

2019 ◽  
Author(s):  
Anna S. Jaeger ◽  
Andrea M. Weiler ◽  
Ryan V. Moriarty ◽  
Sierra Rybarczyk ◽  
Shelby L. O’Connor ◽  
...  
Keyword(s):  
Public Health ◽  
Mouse Model ◽  
Aedes Aegypti ◽  
Vertical Transmission ◽  
Culex Quinquefasciatus ◽  
Zika Virus ◽  
Vector Competence ◽  
Test Vector ◽  
Pathogenic Potential ◽  
Vector Specificity

AbstractSpondweni virus (SPONV) is the most closely related known flavivirus to Zika virus (ZIKV). Its pathogenic potential and vector specificity have not been well defined. SPONV has been found predominantly in Africa, but was recently detected in a pool of Culex quinquefasciatus mosquitoes in Haiti. Here we show that SPONV can cause significant fetal harm, including demise, comparable to ZIKV, in a mouse model of vertical transmission. Following maternal inoculation, we detected infectious SPONV in placentas and fetuses, along with significant fetal and placental histopathology, together indicating vertical transmission. To test vector competence, we exposed Aedes aegypti and Culex quinquefasciatus mosquitoes to SPONV-infected bloodmeals. Aedes aegypti could efficiently transmit SPONV, whereas Culex quinquefasciatus could not. Our results suggest that SPONV has the same features that made ZIKV a public health risk.

Understanding the Public Health Implications of Prisoner Reentry in California: Summary

2009 ◽  
Author(s):  
Lois M. Davis ◽  
Nancy Nicosia ◽  
Adrian Overton ◽  
Lisa Miyashiro ◽  
Kathryn Pitkin Derose ◽  
...  
Keyword(s):  
Public Health ◽  
Prisoner Reentry ◽  
Health Implications ◽  
The Public

Subthreshold Depression in Older Adults: Epidemiology, Illness Course, and Public Health Implications

2011 ◽  
Author(s):  
T. W. Meeks ◽  
I. V. Vahia ◽  
H. Lavretsky ◽  
G. Kulkarni ◽  
D. V. Jeste
Keyword(s):  
Public Health ◽  
Older Adults ◽  
Subthreshold Depression ◽  
Health Implications
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