scholarly journals Ontogenetic and Phylogenetic Approaches for Studying the Mechanisms of Cognitive Dysfunctions

2018 ◽  
Author(s):  
Igor А. Zhuravin ◽  
Nadezhda M. Dubrovskaya ◽  
Natalia L. Tumanova ◽  
Dmitrii S. Vasilev ◽  
Natalia N. Nalivaeva
Keyword(s):  
Cognitive Dysfunctions

Genistein Prevents Hypoxia-Induced Cognitive Dysfunctions by Ameliorating Oxidative Stress and Inflammation in the Hippocampus

2021 ◽  
Author(s):  
Mohammad Rumman ◽  
Shivani Pandey ◽  
Babita Singh ◽  
Mrinal Gupta ◽  
Saba Ubaid ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cognitive Dysfunctions

Cortical neuroinflammation contributes to long-term cognitive dysfunctions following adolescent delta-9-tetrahydrocannabinol treatment in female rats

2015 ◽  
Vol 25 (12) ◽  
pp. 2404-2415 ◽  
Author(s):  
Erica Zamberletti ◽  
Marina Gabaglio ◽  
Pamela Prini ◽  
Tiziana Rubino ◽  
Daniela Parolaro
Keyword(s):  
Female Rats ◽  
Cognitive Dysfunctions

scholarly journals “Kicking and Screaming” or “Gracefully Conceding”: Creative Nonfiction Stories of Aging With Multiple Sclerosis

2021 ◽  
pp. 104973232110098
Author(s):  
Emma V. Richardson ◽  
Robert W. Motl
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Older Adults ◽  
Knowledge Translation ◽  
Creative Nonfiction ◽  
Complex Phenomenon ◽  
Structured Interviews ◽  
Cognitive Dysfunctions ◽  
Positive Experiences

Aging with multiple sclerosis (MS) is a complex phenomenon. Some individuals report physical and cognitive dysfunctions regarding these combined experiences, whereas others report perceived improvements in quality of life. Beyond this, little is known regarding how people make sense of, and come to embody, negative or positive experiences of MS. Thus, our objectives were to (a) explore how people made sense of aging with MS and (b) present this in an artful, engaging, transformative way. To achieve this, we conducted 40 semi-structured interviews with older adults who had MS, analyzed data using pluralistic narrative analyses, and presented results through two creative nonfictions. We detail our process of creating the nonfictions before presenting the different stories of aging with MS, namely “Kicking and Screaming” and “Gracefully Conceding.” We then offer recommendations and implications for using these stories as knowledge translation devices, and further critique the limitations of these stories in practice.

scholarly journals Possibility to predict the development of secondary depression in primary alcoholics during abstinence

2005 ◽  
Vol 62 (11) ◽  
pp. 833-839 ◽  
Author(s):  
Gordana Mandic-Gajic
Keyword(s):  
Alcohol Withdrawal ◽  
Rating Scale ◽  
Test Results ◽  
Cognitive Dysfunctions ◽  
Severity Of Depression ◽  
Primary Male ◽  
Student’S T ◽  
The Relationship ◽  
Degrees Of Severity ◽  
Student’S T Test

Background/Aim. The relationship between alcoholism and depression is observed in clinical trials. The factors which could predict persistence of secondary depression after alcohol withdrawal are not enough explored on admission. The differences between depressed (DA) and non-depressed (NDA) alcoholics regarding the degrees of severity of withdrawal, severity of depression and the intensity of cognitive dysfunctions were explored on admission to investigate possibility of prediction of the development of secondary depression in alcoholics. Methods. A group of primary male alcoholics (n=86) was recruited during inpatient treatment. After 4 weeks alcoholics were divided in the DA group (n=43) and NDA (n=43) group according to the score on the Hamilton Depression Rating Scale (HAM-D). Clinical assessment of withdrawal, scoring on the Alcohol Dependency Severity Scale- ASD, and scoring on the Mini Mental Scale-MMSE were performed in all the participants on admission. The differences between the groups were tested by the Student's t-test. Results. The DA group showed the significantly higher severity of depression, higher levels of alcohol withdrawal symptoms and cognitive dysfunctions than the NDA group on admission. Conclusion. The specific group of depressive alcoholics was shown to be characterized by the higher severity of alcoholism and depression on admission, which could predict prolonged, secondary depression. Early detection and concurrent therapy of secondary depression could improve the treatment, and reduce the relapse of alcoholism.

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