scholarly journals Tailoring of Architecture and Intrinsic Structure of Electrospun Nanofibers by Process Parameters for Tissue Engineering Applications

10.5772/64177 ◽  
2016 ◽  
Author(s):  
Dorota Kolbuk
Keyword(s):  
Tissue Engineering ◽  
Process Parameters ◽  
Electrospun Nanofibers ◽  
Engineering Applications ◽  
Intrinsic Structure

scholarly journals A new design of an electrospinning apparatus for tissue engineering applications

2017 ◽  
Vol 3 (2) ◽  
Author(s):  
Juliana R. Dias ◽  
Cyril Dos Santos ◽  
João Horta ◽  
Pedro Lopes Granja ◽  
Paulo Jorge Da Silva Bartolo
Keyword(s):  
Tissue Engineering ◽  
Simple Technique ◽  
Electrospun Nanofibers ◽  
Processing Parameters ◽  
Wound Dressings ◽  
Engineering Applications ◽  
Electrospinning Technique ◽  
Skin Tissue Engineering ◽  
Spinning Process ◽  
The Stability

The electrospinning technique is being widely explored in the biomedical field due to its simplicity to produce meshes and its capacity to mimic the micro-nanostructure of the natural extracellular matrix. For skin tissue engineering applications, wound dressings made from electrospun nanofibers present several advantages compared to conventional dressings, such as the promotion of the hemostasis phase, wound exudate absorption, semi-permeability, easy conformability to the wound, functional ability and no scar induction. Despite being a relatively simple technique, electrospinning is strongly influenced by polymer solution characteristics, processing parameters and environmental conditions, which strongly determine the production of fibers and their morphology. However, most electrospinning systems are wrongly designed, presenting a large number of conductive components that compromises the stability of the spinning process. This paper presents a new design of an electrospinning system solving the abovementioned limitations. The system was assessed through the production of polycaprolactone (PCL) and gelatin nanofibers.  Different solvents and processing parameters were considered. Results show that the proposed electrospinning system is suitable to produce reproducible and homogeneous electrospun fibers for tissue engineering applications.

Design and characterization of biodegradable multi layered electrospun nanofibers for corneal tissue engineering applications

2019 ◽  
Vol 107 (10) ◽  
pp. 2340-2349 ◽  
Author(s):  
Zohreh Arabpour ◽  
Alireza Baradaran‐Rafii ◽  
Nasrin L. Bakhshaiesh ◽  
Jafar Ai ◽  
Somayeh Ebrahimi‐Barough ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Electrospun Nanofibers ◽  
Corneal Tissue ◽  
Engineering Applications

scholarly journals HTCC-Modified Nanoclay for Tissue Engineering Applications: A Synergistic Cell Growth and Antibacterial Efficiency

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Majid Aliabadi ◽  
Roya Dastjerdi ◽  
Kourosh Kabiri
Keyword(s):  
Tissue Engineering ◽  
Cell Growth ◽  
Cell Attachment ◽  
Exchange Process ◽  
Electrospun Nanofibers ◽  
Chronic Infections ◽  
Engineering Applications ◽  
Antibacterial Efficiency ◽  
Modified Clay ◽  
Modified Montmorillonite

This paper deals with the synthesis of a biocompatible chitosan ammonium salt N-(2-hydroxy) propyl-3-trimethylammonium chitosan chloride (HTCC) and using it in montmorillonite ion-exchange process. HTCC-modified montmorillonite (Mt) with different chemical ratios was successfully synthesized, and their characteristics have been verified by XRD and FTIR analyses. Produced samples have been evaluated in terms of antibacterial efficiency and biocompatibility (cell culture test). Antibacterial efficiency of synthesized HTCC/Mt samples has been confirmed against both gram negative bacteria (Escherichia coli) and gram positive bacteria (Staphylococcus aureus). The results disclosed that the antibacterial efficiency of HTCC-modified montmorillonite was unexpectedly even more than HTCC. This excellent synergistic effect has been referred to entrapping bacteria between the intercalated structures of HTCC-modified montmorillonite. Then HTCC on clay layers can seriously attack and damage the entrapped bacteria. An extraordinary biocompatibility, cell attachment, and cell growth even more than tissue culture polystyrene (TCPS) have been recorded in the case of this novel kind of modified clay. Due to existing concerns about serious and chronic infections after implant placement, this natural-based bioactive and antibacterial modified clay can be used in electrospun nanofibers and other polymeric implants with promising mechanical properties for tissue engineering applications.

Electrospun nanofibers of poly(ε-caprolactone)/depolymerized chitosan for respiratory tissue engineering applications

2016 ◽  
Vol 27 (7) ◽  
pp. 611-625 ◽  
Author(s):  
Christopher Mahoney ◽  
Dawn Conklin ◽  
Jenora Waterman ◽  
Jagannathan Sankar ◽  
Narayan Bhattarai
Keyword(s):  
Tissue Engineering ◽  
Electrospun Nanofibers ◽  
Engineering Applications ◽  
Respiratory Tissue

Electrosprayed nanoparticles and electrospun nanofibers based on natural materials: applications in tissue regeneration, drug delivery and pharmaceuticals

2015 ◽  
Vol 44 (3) ◽  
pp. 790-814 ◽  
Author(s):  
Radhakrishnan Sridhar ◽  
Rajamani Lakshminarayanan ◽  
Kalaipriya Madhaiyan ◽  
Veluchamy Amutha Barathi ◽  
Keith Hsiu Chin Lim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Tissue Regeneration ◽  
Electrospun Nanofibers ◽  
Natural Polymers ◽  
Engineering Applications ◽  
Natural Materials

The role of electrospun and electrosprayed natural polymers or drug ingredients for pharmaceutical and tissue engineering applications is presented in this review.

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