scholarly journals Essential Hypertension in Children: New Mechanistic Insights

10.5772/62652 ◽  
2016 ◽  
Author(s):  
Anne-Maj Sofia Samuelsson
Keyword(s):  
Essential Hypertension ◽  
Hypertension In Children

Genetic Predisposition to Essential Hypertension in Children: Analysis of 17 Single Nucleotide Polymorphisms

2014 ◽  
Vol 5 (4) ◽  
pp. 307-322
Author(s):  
Sergii V. Goncharov ◽  
Veronika L. Gurianova ◽  
Dmytro O. Stro ◽  
Tatyana I. Drevytska ◽  
Sergii P. Kaplinskii ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Single Nucleotide Polymorphisms ◽  
Genetic Predisposition ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Hypertension In Children

Application of the Measurement of Carotid Intima-Media Thickness for Prediction of the Essential Hypertension in Children

2018 ◽  
Vol 69 (6) ◽  
pp. 1550-1553
Author(s):  
Rosana Manea ◽  
Bianca Elena Popovici ◽  
Carmen Daniela Neculoiu ◽  
Dan Minea ◽  
Alina Calin
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Carotid Artery ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Diagnostic Methods ◽  
Control Group ◽  
Study Group ◽  
Media Thickness ◽  
Hypertension In Children

Hypertension is a major risk factor for progression of the atherosclerotic process and for developing of degenerative cardiovascular diseases in adulthood. The aim of this study is to evaluate how the measurement of carotid intima - media thickness for prediction of essential hypertension in children can be used.The study group included 81 children and the control group 61 children, all aged between 5 - 17 years and 11 months old, and admitted in Children Hospital Brasov in the period of 2009 � 2014. The study protocol included: BMI, blood pressure and Doppler echography of the common carotid artery for each group. Mean age of the patients from the study group was 13.67 years, 43.20 % girls and 56.80 % boys, while in the control group, the mean age was 14.07 years, 54.10% girls and 45.90 % boys. 70.37% of the children from the study group presented obesity, while in the control group 40.98% were obese. The IMTC study group ranged from 0.52 - 0.69 mm and the limits of the normotensive subjects were 0.32 -0.54 mm. In both groups the obese patients were found to have increased carotid artery intima-media, which means that IMTC was positively correlated with BMI (p=0.000001).It is necessary to identify diagnostic methods easily applicable for children, allowing involvement of the characteristics of the arterial wall in the degenerative pathological processes. Increased intima-media ratio is positively correlated with high values of blood pressure.

scholarly journals Essential hypertension in children, a growing worldwide problem

2019 ◽  
Vol 24 (1) ◽  
pp. 109 ◽  
Author(s):  
Alaleh Gheissari ◽  
Mohammadreza Sabri ◽  
Marjan Mansourian ◽  
Noushin Mohammadifard ◽  
Nizal Sarrafzadegan
Keyword(s):  
Essential Hypertension ◽  
Hypertension In Children

Pharmacological interventions for essential hypertension in children

2009 ◽  
Author(s):  
Swasti Chaturvedi ◽  
Christoph Licht ◽  
Rulan Parekh ◽  
Jonathan C Craig
Keyword(s):  
Essential Hypertension ◽  
Pharmacological Interventions ◽  
Hypertension In Children

scholarly journals Genetic predisposition to essential hypertension in children: analysis of 17 single nucleotide polymorphisms

2014 ◽  
Vol 59 (6) ◽  
pp. 12-24 ◽  
Author(s):  
Goncharov SV Goncharov SV ◽  
◽  
Gurianova VL Gurianova VL ◽  
Stroy DO Stroy DO ◽  
Drevytska TI Drevytska TI ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Single Nucleotide Polymorphisms ◽  
Genetic Predisposition ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Hypertension In Children

scholarly journals EXPERIENCE AND PROSPECTS FOR ТНЕ USE OF COLLECALCIPHEROL IN ТНЕ COMPLEX TREATMENT OF ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN

2020 ◽  
Vol 26 (3) ◽  
pp. 63-67
Author(s):  
A. V. Dubovaya ◽  
Уи.V. Naumenko
Keyword(s):  
Blood Pressure ◽  
Aqueous Solution ◽  
Vitamin D ◽  
Essential Hypertension ◽  
Arterial Hypertension ◽  
Systolic Blood Pressure ◽  
Vitamin D3 ◽  
Control Group ◽  
Complex Treatment ◽  
Hypertension In Children

The prevalence of arterial hypertension in children ranges from 1 to 25 %, depending on age and the selected criteria. Vitamin D can affect blood pressure (BP) through several mechanisms. The most important function of vitamin D is its role in the regulation of the renin-angiotensin-aldosterone system. The only metabolite of vitamin D that is used to determine its content in the human body is 25 (OH) D (calcidiol). The data on the effect of vitamin D on blood pressure in adolescents are contradictory, indicating a lack of knowledge of this issue. Objective: to evaluate the effectiveness of the use of an aqueous solution of vitamin D3 in the complex treatment of children with essential hypertension. Materials and methods. We examined 30 children (24 boys and 6 girls) aged 13 to 17 years with essential hypertension who had a deficiency of 25 (OH) D in blood serum, the treatment complex of which was supplemented with an aqueous solution of vitamin D3 at 1500 IU/day for 3 months. The control group consisted of 30 children (20 boys and 10 girls) with essential hypertension who received standard therapy. Results. In the main group, after 3 months of taking colecalciferol, a statistically significant normalization of vitamin D levels was documented in 15 (50.0 %) patients, an average of 33.26±1.2 ng/ml. Vitamin D deficiency persisted in 8 (26.6 %) children, vitamin D deficiency persisted in 7 (23.3 %) patients, which served as a basis for increasing the dose of colecalciferol to 2000 IU and continuing to take the drug for another 1 month with a reevaluation serum 25 (OH) D content. A study of the dynamics of blood pressure with the addition of complex treatment with colecalciferol showed that in 24 (80.0 %) children the level of blood pressure decreased, which was statistically significantly more often in comparison with the control group (53.3 %, p<0.05): systolic blood pressure decreased from 142.6±2.4 mm Hg up to 125±0.6 mm Hg (p<0.05), diastolic blood pressure – with 80.2±1.3 mm Hg up to 78.5±1.5 mm Hg. Normalization of blood pressure in the main group was detected after 31±4 days, while in the control group after 60±7 days (p<0.05). There were no adverse reactions during treatment. Conclusions: The positive effect of the drug is proved, which consists in restoring the normal content of 25 (OH) D in blood plasma and reducing systolic blood pressure.

Epidemiology of Essential Hypertension in Children

2004 ◽  
pp. 121-141
Author(s):  
Elaine M. Urbina ◽  
Sathanur R. Srinivasan ◽  
Gerald S. Berenson
Keyword(s):  
Essential Hypertension ◽  
Hypertension In Children

scholarly journals The impact of birth weight and gestational age on the management of juvenile essential hypertension

2015 ◽  
Vol 67 (3) ◽  
pp. 899-901
Author(s):  
Mihai Hogas ◽  
Dragomir Serban ◽  
Lacramioara Serban ◽  
Simona Hogas ◽  
Alin Ciobica ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Birth Weight ◽  
Gestational Age ◽  
Biological Aspect ◽  
Individual Values ◽  
Multiple Risk Factors ◽  
Important Relationship ◽  
The Individual ◽  
The Impact ◽  
Hypertension In Children

Essential hypertension in children is a very important biological aspect in child pathology, caused by the synergic action of multiple risk factors, with an increasing prevalence. Since there is not much knowledge about juvenile essential hypertension in childhood, in this paper we will clarify the existing data about this pathology and its management, mainly by referring to the correlations during different stages. We found significant correlations between hypertension and the individual values of birth weight and gestational age, which suggest that there is an important relationship between birth weight and gestational age, as important biological markers vs. the different stages of essential hypertension.

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