scholarly journals Complementary Therapy with Traditional Chinese Medicine for Treating Atherosclerosis-Related Diseases

10.5772/60704 ◽  
2015 ◽  
Author(s):  
Yu-Chiang Hung ◽  
Chun-Ting Liu ◽  
Wen-Long Hu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Complementary Therapy

Complementary therapy of traditional Chinese medicine for blood sugar control in a patient with type 1 diabetes

2017 ◽  
Vol 30 ◽  
pp. 10-13 ◽  
Author(s):  
Ming-Huei Cheng ◽  
Ching-Liang Hsieh ◽  
Chih-Yu Wang ◽  
Chin-Chuan Tsai ◽  
Che-Chang Kuo
Keyword(s):  
Type 1 Diabetes ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Blood Sugar ◽  
Complementary Therapy

scholarly journals Traditional Chinese Medicine for Refractory Nephrotic Syndrome: Strategies and Promising Treatments

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Xiao-Qin Wang ◽  
Lan Wang ◽  
Yuan-Chao Tu ◽  
Yuan Clare Zhang
Keyword(s):  
Nephrotic Syndrome ◽  
Chinese Medicine ◽  
Herbal Medicine ◽  
Traditional Chinese Medicine ◽  
Kidney Diseases ◽  
Immunosuppressive Agents ◽  
Complementary Therapy ◽  
Great Promise ◽  
Serious Adverse Events ◽  
Refractory Nephrotic Syndrome

Refractory nephrotic syndrome (RNS) is an immune-related kidney disease with poor clinical outcomes. Standard treatments include corticosteroids as the initial therapy and other immunosuppressants as second-line options. A substantial proportion of patients with RNS are resistant to or dependent on immunosuppressive drugs and often experience unremitting edema and proteinuria, cycles of remission and relapse, and/or serious adverse events due to long-term immunosuppression. Traditional Chinese medicine has a long history of treating complicated kidney diseases and holds great potential for providing effective treatments for RNS. This review describes the Chinese medical theories relating to the pathogenesis of RNS and discusses the strategies and treatment options using Chinese herbal medicine. Available preclinical and clinical evidence strongly supports the integration of traditional Chinese medicine and Western medicine for improving the outcome of RNS. Herbal medicine such as Astragalus membranaceus, Stephania tetrandra S. Moore, and Tripterygium wilfordii Hook F can serve as the alternative therapy when patients fail to respond to immunosuppression or as the complementary therapy to improve therapeutic efficacy and reduce side effects of immunosuppressive agents. Wuzhi capsules (Schisandra sphenanthera extract) with tacrolimus and tetrandrine with corticosteroids are two herb-drug combinations that have shown great promise and warrant further studies.

scholarly journals Potential Complementary Therapy for Adverse Drug Reactions to Sulfonamides: Chemoprotection Against Oxidative and Nitrosative Stress by TCM Constituents and Defined Mixtures

2015 ◽  
Vol 18 (4) ◽  
pp. 528 ◽  
Author(s):  
Lee Zhang ◽  
Dao-feng Chen ◽  
Xue Yan Xia ◽  
Cindy Yip ◽  
Michael John Rieder ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Adverse Drug Reactions ◽  
Nitrosative Stress ◽  
Complementary Therapy ◽  
Metabolic Clearance ◽  
Drug Reactions ◽  
Sulfa Drugs ◽  
Oxidative And Nitrosative Stress ◽  
Causative Factors

PURPOSE: Our working hypothesis is that bioactive phytochemicals that are important constituents of Traditional Chinese Medicine and their defined mixtures have potential as complementary therapy for chemoprotection against adverse drug reactions whose toxicity is not related to the pharmacological action of the drug but where oxidative and nitrosative stress are causative factors. METHODS: In this investigation we measured cytotoxicity, lipid peroxidation, protein carbonylation and ROS/NOS-mediated changes in the disulfide proteome of Jurkat E6.1 cells resulting from exposure to sulfamethoxazole N-hydroxylamine with or without pre-treatment with low µM concentrations of baicalein, crocetin, resveratrol and schisanhenol alone and in defined mixtures to compare the ability of these treatment regimens to protect against ROS/RNS toxicity to Jurkat E6.1 cells in culture. RESULTS: Each of the Traditional Chinese Medicine constituents and defined mixtures tested had significant chemoprotective effects against the toxicity of ROS/RNS formed by exposure of Jurkat E6.1 cells to reactive metabolites of sulfamethoxazole implicated as the causative factors in adverse drug reactions to sulfa drugs used for therapy. At equimolar concentrations, the defined mixtures tended to be more effective chemoprotectants overall than any of the single constituents against ROS/RNs toxicity in this context. CONCLUSIONS: At low µM concentrations, defined mixtures of TCM constituents that contain ingredients with varied structures and multiple mechanisms for chemoprotection have excellent potential for complementary therapy with sulfa drugs to attenuate adverse effects caused by oxidative/nitrosative stress. Typically, such mixtures will have a combination of immediate activity due to short in vivo half-lives of some ingredients cleared rapidly following metabolism by phase 2 conjugation enzymes; and some ingredients with more prolonged half-lives and activity reliant on phase 1 oxidation enzymes for their metabolic clearance. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

scholarly journals Use of Chinese medicine in the prevention and treatment of COVID-19 in China and Asia

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Siukan Law ◽  
Chuanshan Xu ◽  
Albert Wingnang Leung
Keyword(s):  
Immune System ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Complementary Therapy ◽  
Syndrome Differentiation ◽  
Content Type ◽  
Patent Medicines ◽  
Chinese Herbal ◽  
Prevention And Treatment ◽  
The Usa

PurposeThe purpose of this paper is to describe and discuss the use of Chinese medicine in the prevention and treatment of coronavirus disease 2019 (COVID-19) in China and Asia.Design/methodology/approachThis paper provides a brief overview of the COVID-19. Based on the syndrome differentiation (辨證論治), the concept of clearing heat and detoxifying lung in traditional Chinese medicine is used to prevent and treat COVID-19 through restoring the vital qi (正氣) in human body and regulating the lung as well as spleen to strengthen the immune system. Traditional Chinese medicine has been used as a complementary therapy for the possible intervention of COVID-19 including traditional Chinese herbal decoctions, Chinese traditional patent medicines, acupuncture and moxibustion as well as the traditional health exercises in China and parts of Asia.FindingsTraditional Chinese medicine plays a significant role in the prevention and treatment of COVID-19 pandemic. The infection cases of China are around 80,000 and a steady decline compared with the USA which has 5,000,000 infection cases and continuous increases. It is shown that more than 90% of patients recovered after the treatment of traditional Chinese herbal decoctions and Chinese traditional patent medicines without any side-effect compared to the use of Remdesivir (GS-5734). Acupuncture (針灸) and moxibustion (艾灸) stimulate the immune and nervous systems for preventing infectious diseases. Taichi (太極) and Baduanjin (八段錦) as the auxiliary aerobic exercise under the theory of Chinese medicine can enhance the immune system and improve the lung function. Thus, an integration of traditional Chinese Medicine and Western medicine is the best strategy for the prevention, treatment and control of COVID-19 pandemic in the future.Originality/valueThis paper describes traditional Chinese medicine as an effective way for the prevention and treatment of COVID-19.

scholarly journals Proteomics in Traditional Chinese Medicine with an Emphasis on Alzheimer’s Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-17 ◽  
Author(s):  
Yanuar Alan Sulistio ◽  
Klaus Heese
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Chinese Philosophy ◽  
Ubiquitin Proteasome System ◽  
Complementary Therapy ◽  
Mechanisms Of Action ◽  
Medical Society ◽  
Increasing Demand

In recent years, there has been an increasing worldwide interest in traditional Chinese medicine (TCM). This increasing demand for TCM needs to be accompanied by a deeper understanding of the mechanisms of action of TCM-based therapy. However, TCM is often described as a concept of Chinese philosophy, which is incomprehensible for Western medical society, thereby creating a gap between TCM and Western medicine (WM). In order to meet this challenge, TCM research has applied proteomics technologies for exploring the mechanisms of action of TCM treatment. Proteomics enables TCM researchers to oversee various pathways that are affected by treatment, as well as the dynamics of their interactions with one another. This review discusses the utility of comparative proteomics to better understand how TCM treatment may be used as a complementary therapy for Alzheimer’s disease (AD). Additionally, we review the data from comparative AD-related TCM proteomics studies and establish the relevance of the data with available AD hypotheses, most notably regarding the ubiquitin proteasome system (UPS).

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