scholarly journals Equal Frequency Surface

10.5772/59887 ◽  
2015 ◽  
Author(s):  
G. Alagappan
Keyword(s):  
2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Saeed Shoar ◽  
Fernando H Centeno ◽  
Daniel M Musher

Abstract Background Long regarded as the second most common cause of community-acquired pneumonia (CAP), Haemophilus influenzae has recently been identified with almost equal frequency as pneumococcus in patients hospitalized for CAP. The literature lacks a detailed description of the presentation, clinical features, laboratory and radiologic findings, and outcomes in Haemophilus pneumonia. Methods During 2 prospective studies of patients hospitalized for CAP, we identified 33 patients with Haemophilus pneumonia. In order to provide context, we compared clinical findings in these patients with findings in 36 patients with pneumococcal pneumonia identified during the same period. We included and analyzed separately data from patients with viral coinfection. Patients with coinfection by other bacteria were excluded. Results Haemophilus pneumonia occurred in older adults who had underlying chronic lung disease, cardiac conditions, and alcohol use disorder, the same population at risk for pneumococcal pneumonia. However, in contrast to pneumococcal pneumonia, patients with Haemophilus pneumonia had less severe infection as shown by absence of septic shock on admission, less confusion, fewer cases of leukopenia or extreme leukocytosis, and no deaths at 30 days. Viral coinfection greatly increased the severity of Haemophilus, but not pneumococcal pneumonia. Conclusions We present the first thorough description of Haemophilus pneumonia, show that it is less severe than pneumococcal pneumonia, and document that viral coinfection greatly increases its severity. These distinctions are lost when the label CAP is liberally applied to all patients who come to the hospital from the community for pneumonia.


2010 ◽  
Vol 2010 ◽  
pp. 1-10 ◽  
Author(s):  
Paromita Raychaudhury ◽  
Ashis K. Basu

-Radiation-induced intrastrand guanine-thymine cross-link, G[8,5-Me]T, hinders replicationin vitroand is mutagenic in mammalian cells. Herein we reportin vitrotranslesion synthesis of G[8,5-Me]T by human and yeast DNA polymerase (hPol and yPol ). dAMP misincorporation opposite the cross-linked G by yPol was preferred over correct incorporation of dCMP, but further extension was 100-fold less efficient for :A compared to :C. For hPol , both incorporation and extension were more efficient with the correct nucleotides. To evaluate translesion synthesis in the presence of all four dNTPs, we have developed a plasmid-based DNA sequencing assay, which showed that yPol was more error-prone. Mutational frequencies of yPol and hPol were 36% and 14%, respectively. Targeted was the dominant mutation by both DNA polymerases. But yPol induced targeted in 23% frequency relative to 4% by hPol . For yPol , targeted and constituted 83% of the mutations. By contrast, with hPol , semi-targeted mutations (7.2%), that is, mutations at bases near the lesion, occurred at equal frequency as the targeted mutations (6.9%). The kind of mutations detected with hPol showed significant similarities with the mutational spectrum of G[8,5-Me]T in human embryonic kidney cells.


1984 ◽  
Vol 54 (2) ◽  
pp. 467-471 ◽  
Author(s):  
Gene D. Steinhauer

Numerous prior studies have reported that rats, pigeons, and humans prefer predictable over unpredictable rewards of equal frequency and magnitude. A frustration-theory analysis of this preference suggests that it obtains because the unpredictable partial reinforcement procedure is aversive whereas the predictable discrimination procedure loses its aversiveness. The preference, on such an analysis, arises due to the tendency to avoid the unpredictable of two alternatives. Since frustration varies as a function of magnitude of reward, the avoidance tendency should increase with increases in reward magnitude in the unpredictable alternative. One group of rats in the present study showed a clear preference for seven versus five 45-mg Noyes Pellets. A second group showed the oft reported preference for five pellets predictable versus five pellets unpredictable. A third group of rats showed a preference for a five-pellet predictable reward over a seven-pellet unpredictable reward. The results of this experiment provide evidence for a frustration-theory analysis of the preference for predictable reward.


Parasitology ◽  
1989 ◽  
Vol 99 (2) ◽  
pp. 157-163 ◽  
Author(s):  
W. Jarra ◽  
K. N. Brown

SummaryDuring the early stages of the primary Plasmodium chabaudi chabaudi AS parasitaemia in CBA/Ca mice this parasite invaded normocytes, but as the parasitaemia developed increasing numbers of parasites were seen within reticulocytes. During and just after peak parasitaemia, as further parasite replication was controlled, the ‘crisis’ phase ensued, mice became increasingly anaemic and reticulocyte numbers were markedly increased. As the parasitaemia was resolved during crisis in excess of 25% of parasites had invaded reticulocytes. In phenylhydrazine-pretreated mice with artificially high reticulocyte levels and infected with P. c. chabaudi AS, normocyte/reticulocyte invasion occurred with equal frequency. No reduction in the infectivity of parasite populations developing in reticulocytes was observed.


1976 ◽  
Vol 7 (2) ◽  
pp. 183-189 ◽  
Author(s):  
Esther Balkin ◽  
Carole Epstein ◽  
David Bush

Fifty black inner-city children and fifty white suburban children were asked their views on discussing death in the classroom. The suburban upper-middle class children were significantly more likely to think that death should be discussed in the classroom. The reasons given for not wanting to discuss death also differed between the two groups. In urban children fear of bad things happening and unwanted emotions were the most frequent responses. In suburban children unwanted emotions was the most frequent response. A better understanding of death and preparation for loss were cited with equal frequency as reasons for discussing death by suburban children. The most frequently occurring response among those urban children who were positive toward discussing death was a better understanding of death. Some implications for death education were presented.


1980 ◽  
Vol 29 (3-4) ◽  
pp. 143-160 ◽  
Author(s):  
Rahul Mukerjee

This paper shows that the criterion of proportional frequency for (unblocked) orthogonal fractional factorial plans, as suggested by some previous authors, is not generally true. On the other hand, the criterion of equal frequency has been established as a necessary and sufficient condition in the general case. Some other properties of orthogonal fractional factorial plans have been investigated. A necessary and sufficient condition for designs involving two or more blocks has also been presented. A broad class of non-existence results follow.


Author(s):  
Weiwen Wang ◽  
Robert Lanfear

Abstract The chloroplast genome usually has a quadripartite structure consisting of a large single copy region and a small single copy region separated by two long inverted repeats. It has been known for some time that a single cell may contain at least two structural haplotypes of this structure, which differ in the relative orientation of the single copy regions. However, the methods required to detect and measure the abundance of the structural haplotypes are labour-intensive, and this phenomenon remains understudied. Here we develop a new method, Cp-hap, to detect all possible structural haplotypes of chloroplast genomes of quadripartite structure using long-read sequencing data. We use this method to conduct a systematic analysis and quantification of chloroplast structural haplotypes in 61 land plant species across 19 orders of Angiosperms, Gymnosperms and Pteridophytes. Our results show that there are two chloroplast structural haplotypes which occur with equal frequency in most land plant individuals. Nevertheless, species whose chloroplast genomes lack inverted repeats or have short inverted repeats have just a single structural haplotype. We also show that the relative abundance of the two structural haplotypes remains constant across multiple samples from a single individual plant, suggesting that the process which maintains equal frequency of the two haplotypes operates rapidly, consistent with the hypothesis that flip-flop recombination mediates chloroplast structural heteroplasmy. Our results suggest that previous claims of differences in chloroplast genome structure between species may need to be revisited.


Perception ◽  
1974 ◽  
Vol 3 (3) ◽  
pp. 303-308 ◽  
Author(s):  
P R Coles

A study of portrait paintings by various artists revealed that the sitter's face is more likely to be illuminated by a light source to the artist's left than to his right. Although the sitter's face may be turned towards the artist's left or right side with equal frequency, the interaction of illumination and profile orientation does not appear to be arbitrary. This finding is interpreted in the context of other findings on left and right in picture perception, and a new explanation of the relationship between profile orientation and the personality of the sitter is offered.


2005 ◽  
Vol 11 (6) ◽  
pp. 424-431 ◽  
Author(s):  
Hugh Series ◽  
Pilar Dégano

Sexually disinhibited behaviours are quite common (prevalence 2–17%) in people with dementia, occurring with about equal frequency in men and women. Assessment of the behaviours, the contexts in which they arise and their risks is essential. It is important to manage the environment and to educate and discuss the issues with carers and families. Behavioural measures are helpful, although no specific behavioural intervention has been shown to be effective in this area. Several classes of drug may help to control the behaviours, but all are potentially harmful and none is licensed for hypersexuality in this population.


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