scholarly journals Pharmacokinetic Properties and Safety of Cadmium-Containing Quantum Dots as Drug Delivery Systems

10.5772/58553 ◽  
2014 ◽  
Author(s):  
Lourdes Rodriguez-Fragoso ◽  
Ivonne Gutiérrez-Sancha ◽  
Patricia Rodríguez-Fragoso ◽  
Anahí Rodríguez-López ◽  
Jorge Reyes-Esparza
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Pharmacokinetic Properties

Carbon Nanotubes, Quantum Dots and Dendrimers as Potential Nanodevices for Nanotechnology Drug Delivery Systems

2013 ◽  
Vol 6 (3) ◽  
pp. 2113-2124
Author(s):  
Prashant Malik ◽  
Neha Gulati ◽  
Raj Kaur Malik ◽  
Upendra Nagaich
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Quantum Dots ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Atomic Scale ◽  
Sustained Drug Delivery ◽  
Pharmaceutical Nanotechnology ◽  
Conventional Device

Nanotechnology deal with the particle size in nanometers. Nanotechnology is ranging from extensions of conventional device physics to completely new approaches based upon molecular self assembly, from developing new materials with dimensions on the nanoscale to direct control of matter on the atomic scale. In nanotechnology mainly three types of nanodevices are described: carbon nanotubes, quantum dots and dendrimers. It is a recent technique used as small size particles to treat many diseases like cancer, gene therapy and used as diagnostics. Nanotechnology used to formulate targeted, controlled and sustained drug delivery systems. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy as nanomaterials and as devices like drug delivery, diagnostic, imaging and biosensor materials. Pharmaceutical nanotechnology has provided more fine tuned diagnosis and focused treatment of disease at a molecular level.    

scholarly journals Synthesis of graphene quantum dots and their applications in drug delivery

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Changhong Zhao ◽  
Xuebin Song ◽  
Ya Liu ◽  
Yifeng Fu ◽  
Lilei Ye ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery Systems ◽  
Graphene Quantum Dots ◽  
Delivery Systems ◽  
Core Shell ◽  
Recent Advances ◽  
Prospective Application

Abstract This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.

Quantum dots synthesis and biological applications as imaging and drug delivery systems

2010 ◽  
Vol 30 (4) ◽  
pp. 283-301 ◽  
Author(s):  
Onyechi Obonyo ◽  
Emma Fisher ◽  
Mark Edwards ◽  
Dennis Douroumis
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Biological Applications

Targeting Cancer using Curcumin Encapsulated Vesicular Drug Delivery Systems

2020 ◽  
Vol 26 ◽  
Author(s):  
Joel Hardwick ◽  
Jack Taylor ◽  
Meenu Mehta ◽  
Saurabh Satija ◽  
Keshav R. Paudel ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Therapeutic Potential ◽  
Drug Carriers ◽  
Delivery Systems ◽  
Limiting Factors ◽  
Drug Bioavailability ◽  
Pharmacokinetic Properties ◽  
Anti Oxidant ◽  
Novel Drug

: Curcumin is a major curcuminoid present in turmeric. The compound is attributed with various therapeutic properties, which include, anti-oxidant, anti-inflammatory, anti-bacterial, anti-malarial, and neuroprotection. Due to its therapeutic potential, curcumin has been employed for centuries in treating different ailments. Curcumin has been investigated lately as a novel therapeutic agent in the treatment of cancer. However, the mechanisms by which curcumin exerts its cytotoxic effects on malignant cells are still not fully understood. One of the main limiting factors in the clinical use of curcumin is its poor bioavailability and rapid elimination. Advancements in drug delivery systems such as, nanoparticle based vesicular drug delivery platforms have improved several parameters, namely, drug bioavailability, solubility, stability, and controlled release properties. The use of curcumin-encapsulated niosomes to improve the physical and pharmacokinetic properties of curcumin is one such approach. This review provides an up-to-date summary on nanoparticle based vesicular drug carriers and their therapeutic applications. Specifically, we focus on niosomes as novel drug delivery formulations and their potential in improving the delivery of challenging small molecules, including curcumin. Overall, the applications of such carriers will provide a new direction for novel pharmaceutical drug delivery, as well as, biotechnology, nutraceutical, and functional food industries.

scholarly journals Fluorescent graphene quantum dots as traceable, pH-sensitive drug delivery systems

2015 ◽  
pp. 6709 ◽  
Author(s):  
Hong Liu ◽  
Jichuan Qiu ◽  
Ruibin Zhang ◽  
Jianhua Li ◽  
Yuanhua Sang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery Systems ◽  
Graphene Quantum Dots ◽  
Delivery Systems ◽  
Ph Sensitive

Fabrication of PEGylated graphitic carbon nitride quantum dots as traceable, pH-sensitive drug delivery systems

2018 ◽  
Vol 42 (17) ◽  
pp. 14263-14270 ◽  
Author(s):  
Jian Dong ◽  
Yanli Zhao ◽  
Hongyu Chen ◽  
Li Liu ◽  
Wenxian Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery Systems ◽  
Carbon Nitride ◽  
Cell Imaging ◽  
Delivery Systems ◽  
Ph Sensitive ◽  
Graphitic Carbon ◽  
Graphitic Carbon Nitride

Fluorescent PEGylated carbon nitride quantum dots are synthesized and characterized for traceable drug delivery and cell imaging.

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

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