Fabrication of PEGylated graphitic carbon nitride quantum dots as traceable, pH-sensitive drug delivery systems

2018 ◽  
Vol 42 (17) ◽  
pp. 14263-14270 ◽  
Author(s):  
Jian Dong ◽  
Yanli Zhao ◽  
Hongyu Chen ◽  
Li Liu ◽  
Wenxian Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery Systems ◽  
Carbon Nitride ◽  
Cell Imaging ◽  
Delivery Systems ◽  
Ph Sensitive ◽  
Graphitic Carbon ◽  
Graphitic Carbon Nitride

Fluorescent PEGylated carbon nitride quantum dots are synthesized and characterized for traceable drug delivery and cell imaging.

Facile synthesis of oxygen and sulfur co-doped graphitic carbon nitride fluorescent quantum dots and their application for mercury(ii) detection and bioimaging

2015 ◽  
Vol 3 (1) ◽  
pp. 73-78 ◽  
Author(s):  
Ya-Chun Lu ◽  
Jia Chen ◽  
Ai-Jun Wang ◽  
Ning Bao ◽  
Jiu-Ju Feng ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Carbon Nitride ◽  
Cell Imaging ◽  
Graphitic Carbon ◽  
Graphitic Carbon Nitride ◽  
Facile Synthesis ◽  
One Step ◽  
Co Doped

We developed a facile one-step route for the synthesis of blue fluorescent OS-GCNQDs, which exhibited improved selectivity and sensitivity for Hg2+ detection, and lower cytotoxicity for cell imaging.

scholarly journals Fluorescent graphene quantum dots as traceable, pH-sensitive drug delivery systems

2015 ◽  
pp. 6709 ◽  
Author(s):  
Hong Liu ◽  
Jichuan Qiu ◽  
Ruibin Zhang ◽  
Jianhua Li ◽  
Yuanhua Sang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery Systems ◽  
Graphene Quantum Dots ◽  
Delivery Systems ◽  
Ph Sensitive

Carbon Nanotubes, Quantum Dots and Dendrimers as Potential Nanodevices for Nanotechnology Drug Delivery Systems

2013 ◽  
Vol 6 (3) ◽  
pp. 2113-2124
Author(s):  
Prashant Malik ◽  
Neha Gulati ◽  
Raj Kaur Malik ◽  
Upendra Nagaich
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Quantum Dots ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Atomic Scale ◽  
Sustained Drug Delivery ◽  
Pharmaceutical Nanotechnology ◽  
Conventional Device

Nanotechnology deal with the particle size in nanometers. Nanotechnology is ranging from extensions of conventional device physics to completely new approaches based upon molecular self assembly, from developing new materials with dimensions on the nanoscale to direct control of matter on the atomic scale. In nanotechnology mainly three types of nanodevices are described: carbon nanotubes, quantum dots and dendrimers. It is a recent technique used as small size particles to treat many diseases like cancer, gene therapy and used as diagnostics. Nanotechnology used to formulate targeted, controlled and sustained drug delivery systems. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy as nanomaterials and as devices like drug delivery, diagnostic, imaging and biosensor materials. Pharmaceutical nanotechnology has provided more fine tuned diagnosis and focused treatment of disease at a molecular level.    

Recent Progress in Stimuli Responsive Intelligent Nano Scale Drug Delivery Systems: A special focus towards pH sensitive systems

2021 ◽  
Vol 22 ◽  
Author(s):  
Vaidevi Sethuraman ◽  
Kumar Janakiraman ◽  
Venkateshwaran Krishnaswami ◽  
Ruckmani Kandasamy
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Drug Delivery Systems ◽  
Disease Diagnosis ◽  
Delivery Systems ◽  
Ph Sensitive ◽  
Special Focus ◽  
Stimuli Responsive ◽  
Ph Variation ◽  
Responsive Systems

Abstract: Stimuli responsive nanocarriers are gaining much attention due to its versatile multifunctional activities including disease diagnosis and treatment. Recently, clinical applications of nano drug delivery systems for cancer treatment make a considerable challenge due to its limited cellular uptake, low bioavailability, poor targetability, stability issues, and unfavourable pharmacokinetics. To overcome these issues researchers are focussing on stimuli responsive systems. Nano carriers elicit its role through endogenous (pH, temperature, enzyme and redox) or exogenous (temperature, light, magnetic field, ultrasound) stimulus. These systems were designed to overcome the shortcomings such as non-specificity and toxicity associated with the conventional drug delivery systems. The pH variation between healthy cells and tumor microenvironment creates a platform towards the generation of pH sensitive nano delivery systems. Herein, we propose to present an overview of various internal and external stimuli responsive behavior based drug delivery systems. Herein the present review will focus specifically on the significance of various pH- responsive nanomaterials such as polymeric nanoparticles, nano micelles, inorganic based pH sensitive drug delivery carriers such as calcium phosphate nanoparticles, and carbon dots in cancer treatment. Moreover, this review elaborates the recent findings on pH based stimuli responsive drug delivery system with special emphasis towards our reported stimuli responsive systems for cancer treatment.

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