scholarly journals Human Leucocyte Antigen Matching Strategy

Author(s):  
Yuying Sun ◽  
Yongzhi Xi
Author(s):  
Julia Schulte-Cloos ◽  
Paul C. Bauer

AbstractWhile a large body of literature empirically documents an electoral advantage for local candidates, the exact mechanisms accounting for this effect remain less clear. We integrate theories on the political geography of candidate-voter relations with socio-psychological accounts of citizens’ local attachment, arguing that citizens vote for candidates from their own local communities as an expression of their place-based identity. To test our argument, we exploit a unique feature of the German mixed-member electoral system. We identify the causal effect of candidates’ localness by relying on within-electoral-district variation coupled with a geo-matching strategy on the level of municipalities ($$\hbox {N}=11175$$ N = 11175 ). The results show that voters exhibit a strong bias in favor of local candidates even when they are not competitive. More than only expecting particularistic benefits from representatives, citizens appear to vote for candidates from their own local community to express their place-based social identity.


Rheumatology ◽  
2020 ◽  
Author(s):  
Jyoti Ranjan Parida ◽  
Sandeep Kumar ◽  
Sakir Ahmed ◽  
Smriti Chaurasia ◽  
Ratnadeep Mukherjee ◽  
...  

Abstract Objectives Peripheral SpA (pSpA) is comprised of ReA, PsA, enteritis-associated arthritis and undifferentiated pSpA (upSpA). ReA and upSpA share T cell oligotypes and metabolomics in serum and SF. We investigated HLA-B27 subtypes and cytokines in serum and SF that were compared between ReA and upSpA. Methods ReA and upSpA were compared in two cohorts. In cohort I (44 ReA and 56 upSpA), HLA-B27 subtyping was carried out. In cohort II (17 ReA and 21 upSpA), serum and SF cytokines were compared using a multiplex cytokine bead assay (27 cytokines). A total of 28 healthy controls with similar age and sex to cohort II were included for comparison of serum cytokine levels. Results In cohort I, HLA-B27 was positive in 81.8% (36/44) of ReA and 85.71% (48/56) of upSpA patients. HLA-B27 typing was successful in 70 patients (30 ReA and 40 uSpA). HLA-B*2705 was the most common, followed by HLA-B*2704 and HLA-B*2707. Frequencies were the same between ReA and upSpA. In cohort II, 14 cytokines were detectable in the serum of patients. The levels of eight cytokines were higher than in the controls. The cytokine levels of ReA and upSpA were similar. Sixteen cytokines were detectable in the SF of patients. There was no statistical difference in the levels between ReA and upSpA. The cytokine profiles in sera and SF were also similar among HLA-B27-positive and negative patients. Conclusion ReA and upSpA have similar HLA-B27 subtype associations and similar cytokine profiles. They should be considered as a single entity during studies as well as clinical management.


2016 ◽  
Vol 16 (1) ◽  
pp. 151-183 ◽  
Author(s):  
Renuka Sane ◽  
Susan Thomas

Abstract The paper studies the effect of a law that banned micro-credit lending in the state of Andhra Pradesh in India. Regions in Andhra Pradesh are matched to regions that did not face the ban. A difference-in-difference estimation of changes in matched regions is used to establish a causal impact on average household consumption in the region. The results show that the average household consumption in the ban-affected regions dropped by 15% immediately after the ban compared to the matched regions, and persisted for four quarters. The result is robust to cross-sectional variations in regional exposure to micro-finance prior to the ban, variation in rural and urban locations and variations in matching strategy. The analysis points to a ban as a sub-optimal intervention to improve customer welfare.


2007 ◽  
Vol 139 (3) ◽  
pp. 464-474 ◽  
Author(s):  
Willem J. Van Heeckeren ◽  
Laura R. Fanning ◽  
Howard J. Meyerson ◽  
Pingfu Fu ◽  
Hillard M. Lazarus ◽  
...  

1987 ◽  
Vol 14 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Fujio Numano ◽  
Shuzo Nomura ◽  
Michiyoshi Yajima ◽  
Tadanori Aizawa ◽  
Jun-ichi Fujii ◽  
...  

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