scholarly journals Radiation Therapy and Skin Cancer

10.5772/35843 ◽  
2012 ◽  
Author(s):  
Jonathan D. ◽  
Christopher J. ◽  
David K. ◽  
Glen M.
Keyword(s):  
Radiation Therapy ◽  
Skin Cancer

Reclaim Radiation Therapy for Skin Cancer

2012 ◽  
Vol 43 (8) ◽  
pp. 16
Author(s):  
DAMIAN McNAMARA
Keyword(s):  
Radiation Therapy ◽  
Skin Cancer

scholarly journals Management of Acute Radiodermatitis in Non-Melanoma Skin Cancer Patients Using Electrospun Nanofibrous Patches Loaded with Pinus halepensis Bark Extract

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2596
Author(s):  
Aikaterini Kyritsi ◽  
Stefanos Kikionis ◽  
Anna Tagka ◽  
Nikolaos Koliarakis ◽  
Antonia Evangelatou ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Skin Cancer ◽  
Cancer Patients ◽  
Pinus Halepensis ◽  
Radiation Therapy Oncology Group ◽  
Bark Extract ◽  
Skin Reactions ◽  
Non Melanoma Skin Cancer ◽  
Patient Reported ◽  
Melanoma Skin

Acute radiodermatitis is the most common side effect in non-melanoma skin cancer patients undergoing radiotherapy. Nonetheless, despite the ongoing progress of clinical trials, no effective regimen has been found yet. In this study, a non-woven patch, comprised of electrospun polymeric micro/nanofibers loaded with an aqueous extract of Pinus halepensis bark (PHBE), was fabricated and clinically tested for its efficacy to prevent radiodermatitis. The bioactivity of the PHBE patch was evaluated in comparison with a medical cream indicated for acute radiodermatitis. Twelve volunteer patients were selected and randomly assigned to two groups, applying either the PHBE patch or the reference cream daily. Evaluation of radiation-induced skin reactions was performed during the radiotherapy period and 1 month afterwards according to the Radiation Therapy Oncology Group (RTOG) grading scale, photo-documentation, patient-reported outcomes (Visual Analog Scale, questionnaire), biophysical measurements (hydration, transepidermal water loss, erythema, melanin), and image analysis. In contrast with the reference product, the PHBE patch showed significant anti-inflammatory activity and restored most skin parameters to normal levels 1 month after completion of radiation therapy. No adverse event was reported, indicating that the application of the PHBE patch can be considered as a safe medical device for prophylactic radiodermatitis treatment.

scholarly journals Diffusing Alpha-Emitters Radiation Therapy: Template Based TPS for Brachytherapy of Squamous Cell Skin Cancer

2018 ◽  
Vol 102 (3) ◽  
pp. e491
Author(s):  
G. Feliciani ◽  
S.R. Bellia ◽  
D. Bianchini ◽  
G. Mazzotti ◽  
V. Ravaglia ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Skin Cancer ◽  
Squamous Cell ◽  
Alpha Emitters

Invasive Cutaneous Squamous Cell Carcinoma Presenting as a Nonhealing Radiation Wound

2011 ◽  
Vol 101 (4) ◽  
pp. 360-362
Author(s):  
Stephen J. Longobardi ◽  
Brian Sullivan ◽  
E. Hani Mansour
Keyword(s):  
Squamous Cell Carcinoma ◽  
Radiation Therapy ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Lower Extremities ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Invasive Squamous Cell Carcinoma ◽  
Negative Biopsy

Cutaneous squamous cell carcinoma is the second most common form of skin cancer and accounts for 20% of cutaneous malignancies. We report the case of a patient who presented with a complaint of nonhealing wounds following radiation therapy for the treatment of noninvasive squamous cell carcinoma of both lower extremities. Initial biopsies of the wounds were benign. However, a second biopsy performed approximately 2 months later was found to be positive for invasive squamous cell carcinoma. This case uniquely exemplifies that all nonhealing wounds should be viewed with a critical eye for possible malignancy even in the presence of previous negative biopsy. This is especially true for radiation wounds that may be prone to malignant transformation or recurrence. (J Am Podiatr Med Assoc 101(4): 360–362, 2011)

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