scholarly journals Utility of One Step Immunoassay in Detecting False Negativity in Routine Blood Bank Screening of Infectious Diseases

10.5772/34519 ◽  
2012 ◽  
Author(s):  
Kafil Akhtar
Keyword(s):  
Infectious Diseases ◽  
Blood Bank ◽  
Routine Blood ◽  
One Step

Sensitivity of Routine Blood Bank Methods for the Detection of Anti-D as Determined during Proficiency Testing

1984 ◽  
Vol 82 (3) ◽  
pp. 326-329 ◽  
Author(s):  
Peter H. Pinkerton ◽  
Edna D. Zuber ◽  
Robert M. Barr ◽  
Betty E. E. Croucher ◽  
Marie C. Quantz ◽  
...  
Keyword(s):  
Proficiency Testing ◽  
Blood Bank ◽  
Routine Blood

scholarly journals Seroprevalence of markers of transfusiontransmissible diseases in positive blood donors detected in routine screening in the Blood Bank of Hospital Carlos Luis Valverde Vega, Costa Rica. Period 2015 – 2019

2021 ◽  
Vol 9 (4) ◽  
pp. 70-73
Author(s):  
Jean Pablo Castro-Ruiz
Keyword(s):  
Infectious Diseases ◽  
Blood Donors ◽  
Blood Donation ◽  
Individual Characteristics ◽  
Blood Bank ◽  
Health Centers ◽  
Blood Components ◽  
Blood Banks ◽  
Scientific Ethics ◽  
The Individual

Blood is one of the fundamental tissues of our body. Blood donation allows blood banks to meet hospital needs for blood components. Blood transfusion is an activity that carries a risk, originated by a series of causal actions derived from the individual characteristics of donors and patients. Blood components are biological products and as such, they can never be exempt from the risk of transmitting infectious diseases, such as hepatitis B, HIV, syphilis, among others. Thanks to the investigation of the donor database of the Blood Bank of Hospital Dr. Carlos Luis Valverde Vega and the annual statistics of the blood bank, the statistics referring to donations were obtained, according to the type, grade of acceptance and as well as the prevalence of mandatory screening infectious diseases in the blood bank, between the years 2015 and 2019, with the respective authorization of the corresponding scientific ethics committee. This study reported a prevalence for Anti HB Core of 0.99%, 0.14% for HBsAg, 0.11% for syphilis, 0.05% for hepatitis C, 0.02% for HIV and 0% for the disease de Chagas and HTLV I / II. By using the bases of this work, future analyzes with a similar premise may be developed in different blood banks of the different health centers in our country.

A Flow Cytometric Study of Reagent Cells to Resolve ABO Typing Discrepancy

2020 ◽  
Vol 155 (1) ◽  
pp. 117-123
Author(s):  
Danielle L V Maracaja ◽  
Jesse Qiao ◽  
Tomas Salazar ◽  
James Barry ◽  
Karen LaForce ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Blood Group ◽  
Flow Cytometric Analysis ◽  
Blood Bank ◽  
Blood Group A ◽  
Routine Blood ◽  
Flow Cytometric ◽  
A Cells ◽  
Group A ◽  
Flow Cytometric Study

Abstract Objectives RBC alloantibodies can lead to ABO grouping discrepancies unrelated to A or B antigens or antibodies posing challenges in the blood bank testing. Routine blood bank testing and flow cytometry were used to immunophenotype reagent cells and elucidate the cause of ABO discrepancies in two patients. Methods ABO discrepancy was identified in two patients after transfusion with several units of RBCs. For both patients, the pretransfusion type and screen demonstrated blood group A. Eight and 16 days later, both patients showed an apparent antibody to reagent group A cells, which prompted additional study with patients’ samples and flow cytometric testing of commercial reagent cells. Results In both patients’ specimens, posttransfusion evaluation demonstrated an emerging antibody to the Kell antigen (K). The RBCs of both patients typed negative for K, and both were transfused with K-positive RBCs. Flow cytometric analysis of reagent RBCs demonstrated that five of seven lot numbers were positive for K. Conclusions Emerging anti-K antibody led to agglutination of the K-positive reagent A1 cells, highlighting the importance of considering RBC alloantibodies and the composition of reagent cells when interpreting cases with an apparent ABO grouping discrepancy.

ROUTINE BLOOD BANK REQUESTS IN OBSTETRICS: A SAFE AND EFFECTIVE POLICY 1

1998 ◽  
Vol 5 (3) ◽  
pp. 136-139
Author(s):  
Andrea Ries LT, MC, USNR ◽  
Jerome N Kopelman LTC, MC, USA
Keyword(s):  
Blood Bank ◽  
Routine Blood ◽  
Effective Policy

Is red blood cell rheology preserved during routine blood bank storage?

Transfusion ◽  
2010 ◽  
Vol 50 (4) ◽  
pp. 941-948 ◽  
Author(s):  
Sandra Henkelman ◽  
Margriet J. Dijkstra-Tiekstra ◽  
Janny de Wildt-Eggen ◽  
Reindert Graaff ◽  
Gerhard Rakhorst ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Bank ◽  
Cell Rheology ◽  
Routine Blood

One step closer to precision medicine for infectious diseases

2019 ◽  
Vol 19 (6) ◽  
pp. 564-565 ◽  
Author(s):  
Mathias W Pletz ◽  
Michael Bauer ◽  
Axel A Brakhage
Keyword(s):  
Infectious Diseases ◽  
Precision Medicine ◽  
One Step

scholarly journals D ANTIGEN; CHANCES OF FINDING WEAK D ANTIGEN AND RE-EVALUATION OF ITS CLINICAL SIGNIFICANCE AS A ROUTINE BLOOD BANK PROCEDURE

2016 ◽  
Vol 23 (11) ◽  
pp. 1395-1399
Author(s):  
Dr. Nazish Saqlain ◽  
Dr. Aatika Ahmed ◽  
Dr. Tooba Fateen ◽  
Dr. Nisar Ahmed
Keyword(s):  
Clinical Significance ◽  
Blood Bank ◽  
Routine Blood ◽  
D Antigen

A Case of Acute Hemolysis After Ceftriaxone: Immune Complex Mechanism Demonstrated by Flow Cytometry

2004 ◽  
Vol 128 (8) ◽  
pp. 905-907
Author(s):  
Ram Kakaiya ◽  
Jill Cseri ◽  
Steve Smith; ◽  
Simone Silberman ◽  
Tara C. Rubinas ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Immune Complex ◽  
Hemolytic Anemia ◽  
Autoimmune Hemolytic Anemia ◽  
Blood Bank ◽  
Red Cell ◽  
Complex Mechanism ◽  
Routine Blood ◽  
Ceftriaxone Sodium ◽  
Cell Antibody

Abstract An immune complex mechanism for ceftriaxone sodium– induced severe autoimmune hemolytic anemia has previously been demonstrated using routine blood bank techniques. We describe herein a patient with severe hemolysis that subsided once the drug was discontinued. Serologic techniques demonstrated immune complex–mediated ceftriaxone-dependent red cell antibodies. These findings were further supported by the results of flow cytometry, in which a change in basal red cell autofluorescence was seen in the presence of the antibody and the drug. Our case illustrates the adjunctive value of flow cytometry in the diagnosis of ceftriaxone-dependent red cell antibody.

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