scholarly journals In vivo Toxicity Studies of Pristine Carbon Nanotubes: A Review

10.5772/34201 ◽  
2012 ◽  
Author(s):  
Jelena Kolosnjaj-Tabi ◽  
Henri Szwarc ◽  
Fathi Mouss
Keyword(s):  
Carbon Nanotubes ◽  
In Vivo Toxicity ◽  
Toxicity Studies

In Vivo Toxicity Studies of Chitosan-Coated Cobalt Ferrite Nanocomplex for Its Application as MRI Contrast Dye

2020 ◽  
Vol 3 (11) ◽  
pp. 7952-7964
Author(s):  
Md. Salman Shakil ◽  
Md. Ashraful Hasan ◽  
Md. Forhad Uddin ◽  
Aminul Islam ◽  
Arijun Nahar ◽  
...  
Keyword(s):  
Cobalt Ferrite ◽  
Mri Contrast ◽  
In Vivo Toxicity ◽  
Toxicity Studies

scholarly journals Chemical Characterization of Artemisia Annua L. Extract Assessment of Antioxidant Activity in vitro and in vivo Toxicity Studies

2019 ◽  
Vol 70 (6) ◽  
pp. 1903-1907
Author(s):  
Roxana Liana Stan ◽  
Bogdan Sevastre ◽  
Adriana Corina Hangan ◽  
Sanda Bota ◽  
Daniela Hanganu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Artemisia Annua ◽  
Histopathological Examination ◽  
Haematological Toxicity ◽  
Chemical Characterization ◽  
In Vivo Toxicity ◽  
Artemisia Annua L ◽  
Toxicity Studies

The purpose of the study was to demonstrate in vitro antioxidant activity and in vivo toxicity of the Artemisia Annua L. extract. The plant was harvested from Bihor area (Crisul Repede and Negru river valleys), Romania. Preparation of the plant product and of the lyophilizated extract was carried out in accordance with the Romanian Pharmacopeia Xth Edition. Lyophilized extract was evaluated in terms of polyphenol content using HPLC method. Antioxidant activity was highlighted using the DPPH, ABTS and FRAP methods. Hepatic, renal and haematological toxicity studies have been performed on laboratory mice. For this purpose blood and organs were collected. Biochemical and haematological parameters were determined on the blood samples and histopathological examination was performed on organs. In vitro antioxidant effect of Artemisia Annua L extract and its lack of in vivo toxicity were demonstrated. It is desirable to obtain a new phytoproduct harvested from spontaneous flora of Romania with antioxidant / antitumoral properties and which is devoid of toxicity.

In Vivo Toxicity of Carbon Nanotubes

2012 ◽  
pp. 1077-1083
Author(s):  
Hans Deyhle ◽  
Georg Schulz ◽  
Bert Müller ◽  
Roger H. French ◽  
Roger H. French ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
In Vivo Toxicity

Comparative in vivo toxicity assessment places multiwalled carbon nanotubes at a higher level than mesoporous silica nanoparticles

2016 ◽  
Vol 33 (2) ◽  
pp. 182-192 ◽  
Author(s):  
Nidhi Rawat ◽  
Sandhya ◽  
Kesavan Subaharan ◽  
M Eswaramoorthy ◽  
Gautam Kaul
Keyword(s):  
Carbon Nanotubes ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Multiwalled Carbon Nanotubes ◽  
Mesoporous Silica Nanoparticles ◽  
Treated Group ◽  
Cellular Level ◽  
Multiwalled Carbon ◽  
In Vivo Toxicity

In the present work, we took two nanomaterials (NMs), mesoporous silica nanoparticles (MSNs) and multiwalled carbon nanotubes (MWCNTs), and compared their in vivo toxicity taking albino mice as a test animal model. Presently, conflicting data persist regarding behavior of these NMs with macromolecules like protein and lipid at the cellular level in cell lines as well as in animal models and this generated the interest to study them. The mice were treated orally with a single dose of 50 ppm MWCNTs and intraperitoneally with 10, 25, and 50 mg kg−1 body weight (BW) of MSNs and 1.5, 2.0, and 2.5 mg kg−1 BW of MWCNTs. Liver enzyme markers serum aspartate aminotransferase (AST), alanine aminotransferase, and alkaline phosphatase along with total protein (TP) levels were evaluated 7 days postexposure. No significant differences in organ weight indices or enzyme levels were observed between different treatment doses but there were significant differences between the treatment groups and the controls. Of the three enzymes assayed, AST displayed a peculiar pattern, especially in the MWCNTs intraperitoneally treated group. TP level was significantly increased in the orally treated MWCNTs group. The results showed that MWCNTs even at much smaller doses than MSNs displayed similar toxicity levels, suggesting that toxicity of MWCNTs is greater than MSNs.

In vitro and in vivo toxicity studies of copper sulfide nanoplates for potential photothermal applications

2015 ◽  
Vol 11 (4) ◽  
pp. 901-912 ◽  
Author(s):  
Wei Feng ◽  
Wei Nie ◽  
Yanhua Cheng ◽  
Xiaojun Zhou ◽  
Liang Chen ◽  
...  
Keyword(s):  
Copper Sulfide ◽  
In Vivo Toxicity ◽  
Toxicity Studies
Sign in / Sign up

Export Citation Format

Share Document